Pilot Pharmacokinetic Study in Healthy Adults Using Intravascular Microdialysis Catheters Modified for Use in Paediatric Patients to Assess Vancomycin Blood Levels

Autor: Valentin al Jalali, Martin Bauer, Michael Wölfl-Duchek, Maysa Sarhan, Sebastian G. Wicha, Stefan Poschner, Walter Jäger, Franz König, Christoph Male, Markus Zeitlinger

Publikováno v: Clinical pharmacokinetics.

Exhaustive pharmacokinetic (PK) studies in paediatric patients are unavailable for most antibiotics and feasibility of PK studies is limited by challenges, such as low blood volume and venipuncture-related pain. Microdialysis (MD) represents a promis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abaf7b6b5bf77c172f4d63acb1b5ed9f
https://pubmed.ncbi.nlm.nih.gov/36471223

Immunological consequences of kidney cell death

Autor: Andreas Linkermann, Maysa Sarhan, Rainer Oberbauer, Christian Hugo, Anne von Mässenhausen

Publikováno v: Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 2, Pp 1-15 (2018)

Death of renal cells is central to the pathophysiology of acute tubular necrosis, autoimmunity, necrotizing glomerulonephritis, cystic kidney disease, urosepsis, delayed graft function and transplant rejection. By means of regulated necrosis, immunog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f54a9f8c5dc33de0925e2865a466db0
https://doi.org/10.1038/s41419-017-0057-9

BDNF parabrachio-amygdaloid pathway in morphine-induced analgesia

Autor: Hugues Dardente, Pierre Veinante, Venetia Zachariou, Ralph J. DiLeone, Florent Barthas, Maysa Sarhan, Jennifer Kaufling, Sophie A. Pawlowski, Ipek Yalcin, Michel Barrot

Publikováno v: International Journal of Neuropsychopharmacology
International Journal of Neuropsychopharmacology, Oxford University Press (OUP), 2013, 16 (7), pp.1649-1660. ⟨10.1017/S146114571200168X⟩

In addition to its neurotrophic role, brain-derived neurotrophic factor (BDNF) is involved in a wide array of functions, including anxiety and pain. The central amygdaloid nucleus (CeA) contains a high concentration of BDNF in terminals, originating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb7e1d3f04c6520b3e102543b1c1de0
https://doi.org/10.1017/s146114571200168x

Misleading features of neuroimaging and electroencephalography: insulinoma misdiagnosed as temporal lobe epilepsy

Autor: Constanza Dalvit, A. Benoilid, Jerome Aupy, Maria-Paola Valenti, Maysa Sarhan, Edouard Hirsch

Publikováno v: Epileptic disorders : international epilepsy journal with videotape. 15(1)

Epilepsy is a common disorder but diagnosis remains largely clinical. Although MRI and EEG significantly aid the diagnosis of epilepsy, these techniques may also be misleading and indicate abnormalities not related to phenomenology. Consequences of e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c07a31d0cd937a117ca811968271d6ba
https://pubmed.ncbi.nlm.nih.gov/23531631

Wnt2 Expression and Signaling is Increased by Different Classes of Antidepressant Treatments

Autor: Maysa Sarhan, Samuel S. Newton, Vanja Duric, Matthew J. Girgenti, Hideki Okamoto, Ronald S. Duman, Mounira Banasr, Ralph J. DiLeone, Bhavya Voleti

Background Despite recent interest in glycogen synthase kinase-3β (GSK-3β) as a target for the treatment of mood disorders, there has been very little work related to these illnesses on the upstream signaling molecules that regulate this kinase as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00859d28c9bd074e96fa427c9e0ad52f
https://europepmc.org/articles/PMC2929274/