Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Mayra J Sandoval-Cooper"'
Autor:
Kamlesh K Gupta, Deborah L Donahue, Mayra J Sandoval-Cooper, Francis J Castellino, Victoria A Ploplis
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120728 (2015)
Sepsis-induced acute kidney injury (AKI) contributes to the high mortality and morbidity in patients. Although the pathogenesis of AKI during sepsis is poorly understood, it is well accepted that plasminogen activator inhibitor-1 (PAI-1) and vitronec
Externí odkaz:
https://doaj.org/article/2ebb137a2bcc41899be7cf91e2bfd9aa
Autor:
Francis J Castellino, Zhong Liang, Patrick K Davis, Rashna D Balsara, Harsha Musunuru, Deborah L Donahue, Denise L Smith, Mayra J Sandoval-Cooper, Victoria A Ploplis, Mark Walsh
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52878 (2012)
To delineate the critical features of platelets required for formation and stability of thrombi, thromboelastography and platelet aggregation measurements were employed on whole blood of normal patients and of those with Bernard-Soulier Syndrome (BSS
Externí odkaz:
https://doaj.org/article/39cdca1cd69d4c199bd8fa80aa341c6d
Autor:
Takayuki Iwaki, Tomohiro Arakawa, Mayra J. Sandoval-Cooper, Denise L. Smith, Deborah Donahue, Victoria A. Ploplis, Kazuo Umemura, Francis J. Castellino
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1832 (2021)
The fibrinolytic system has been implicated in the genesis and progression of atherosclerosis. It has been reported that a plasminogen (Pg) deficiency (Plg−/−) exacerbates the progression of atherosclerosis in Apoe−/− mice. However, the manne
Externí odkaz:
https://doaj.org/article/e7d81f77f37642d0a16244a1c592c56f
Autor:
Kamlesh K. Gupta, Deborah L. Donahue, Mayra J. Sandoval-Cooper, Francis J. Castellino, Victoria A. Ploplis
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Plasminogen activator inhibitor-1 (PAI-1) is known to protect mice against cardiac fibrosis. It has been speculated that PAI-1 may regulate cardiac fibrosis by inactivating urokinase-type plasminogen activator (uPA) and ultimately plasmin (P
Externí odkaz:
https://doaj.org/article/b61808fa7a1343d587e54e6e25fbad0a
Autor:
Zonggao Shi, M. Sharon Stack, Jenifer R. Prosperi, Simeon Mining, David Chumba, Laurie E. Littlepage, Sunil Badve, Mayra J. Sandoval-Cooper, Maggie Kerper, Kirtika Patel, Bernard Guyah, Katherine Taylor, Ayub V. Ofulla, Rispah T. Sawe
Publikováno v:
Tropical Medicine and Health
Tropical Medicine and Health, Vol 45, Iss 1, Pp 1-11 (2017)
Tropical Medicine and Health, Vol 45, Iss 1, Pp 1-11 (2017)
Background Tumors commonly are infiltrated by leukocytes, or tumor infiltrating leukocytes (TILs). It remains unclear, however, if the density and type of individual TILs has a direct or simply correlative role in promoting poor prognosis in breast c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a473f57bd1afc27f59c342168b2def
https://pubmed.ncbi.nlm.nih.gov/28794686
https://pubmed.ncbi.nlm.nih.gov/28794686
Autor:
Mayra J. Sandoval-Cooper, Kamlesh K. Gupta, Victoria A. Ploplis, Francis J. Castellino, Deborah L. Donahue
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Plasminogen activator inhibitor-1 (PAI-1) is known to protect mice against cardiac fibrosis. It has been speculated that PAI-1 may regulate cardiac fibrosis by inactivating urokinase-type plasminogen activator (uPA) and ultimately plasmin (Pm) genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c211accd13b5fb0957631646a6f2a0f
http://europepmc.org/articles/PMC5428408
http://europepmc.org/articles/PMC5428408
Autor:
Julia Beck, Victoria A. Ploplis, Robert A. Yount, Francis J. Castellino, Braxton Fritz, Mayra J. Sandoval-Cooper, Deborah L. Donahue, Scott Thomas, Mark Walsh, Patrick Davis
Publikováno v:
Journal of Neurotrauma. 31:404-410
Acute coagulopathy is a serious complication of traumatic brain injury (TBI) and is of uncertain etiology because of the complex nature of TBI. However, recent work has shown a correlation between mortality and abnormal hemostasis resulting from earl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1515554351d173d472106edafc697aba
https://doi.org/10.1089/neu.2013.3089
https://doi.org/10.1089/neu.2013.3089
Autor:
Zonggao Shi, Jun Li, Maggie Kerper, Kirtika Patel, Jingmeng Xie, Laurie E. Littlepage, David Chumba, M. Sharon Stack, Rispah T. Sawe, Katherine Taylor, Jenifer R. Prosperi, Ayub V. Ofulla, Simeon Mining, Sunil Badve, Mayra J. Sandoval-Cooper
Publikováno v:
BMC Cancer
Background Breast cancer incidence and mortality vary significantly among different nations and racial groups. African nations have the highest breast cancer mortality rates in the world, even though the incidence rates are below those of many nation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c922af8b99c5ad66e996fe3107ab57
https://doi.org/10.1186/s12885-016-2204-6
https://doi.org/10.1186/s12885-016-2204-6
Autor:
Victoria A. Ploplis, Stefania Vetrano, Deborah L. Donahue, Emanuela Sala, Alberto Malesci, Mayra J. Sandoval-Cooper, Antonino Spinelli, Alessandro Repici, Francis J. Castellino, Vincenzo Arena, Silvio Danese, Carmen Correale
Publikováno v:
Proceedings of the National Academy of Sciences. 108:19830-19835
The protein C (PC) pathway is a well-characterized coagulation system. Endothelial PC receptors and thrombomodulin mediate the conversion of PC to its activated form, a potent anticoagulant and anti-inflammatory molecule. Here we show that the PC pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461acdbed7445a5763165778f5244803
https://doi.org/10.1073/pnas.1107140108
https://doi.org/10.1073/pnas.1107140108
Autor:
Francisco Noria, Deborah L. Donahue, Francis J. Castellino, Haifeng Xu, Mayra J. Sandoval-Cooper, H Menchen, Victoria A. Ploplis
Publikováno v:
The Journal of Pathology. 217:362-371
Mice genetically modified to produce low levels (approximately 1% of wild-type) of coagulation FVII presented with echocardiographic evidence of heart abnormalities. Decreases in ventricular size and reductions in systolic and diastolic functions wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7248da2ba7dd9a56f6f5fa3660811164
https://doi.org/10.1002/path.2454
https://doi.org/10.1002/path.2454