Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Mayra Furlan‐Magaril"'
Autor:
Aura Stephenson-Gussinye, Luis A. Rendón-Bautista, Blanca E. Ruiz-Medina, Eduardo Blanco-Olais, Rosario Pérez-Molina, Cleofas Marcial-Medina, Yanin Chavarri-Guerra, Enrique Soto-Pérez-de-Celis, Andrea Morales-Alfaro, Ayerim Esquivel-López, Fernando Candanedo-González, Armando Gamboa-Domínguez, Rubén Cortes-González, Alejandro Alfaro-Goldaracena, Sara E. Vázquez-Manjarrez, Guido Grajales-Figueroa, Beatriz Astudillo-Romero, Jesús Ruiz-Manriquez, A. César Poot-Hernández, Paula Licona-Limón, Mayra Furlan-Magaril
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Molecular and cellular characterization of tumors is essential due to the complex and heterogeneous nature of cancer. In recent decades, many bioinformatic tools and experimental techniques have been developed to achieve personalized characterization
Externí odkaz:
https://doaj.org/article/331fba8ae42c45d880cce5649e067768
A novel cis-regulatory element regulates αD and αA-globin gene expression in chicken erythroid cells
Autor:
Josué Cortés-Fernández de Lara, Hober Nelson Núñez-Martínez, Gustavo Tapia-Urzúa, Sylvia Garza-Manero, Carlos Alberto Peralta-Alvarez, Mayra Furlan-Magaril, Edgar González-Buendía, Martín Escamilla-Del-Arenal, Andrea Casasola, Georgina Guerrero, Felix Recillas-Targa
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
BackgroundCis-regulatory elements (CREs) play crucial roles in regulating gene expression during erythroid cell differentiation. Genome-wide erythroid-specific CREs have not been characterized in chicken erythroid cells, which is an organism model us
Externí odkaz:
https://doaj.org/article/a67160efa3d34c05b6aed6d389f004ad
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
3D genome organization regulates gene expression in different physiological and pathological contexts. Characterization of chromatin structure at different scales has provided information about how the genome organizes in the nuclear space, from chro
Externí odkaz:
https://doaj.org/article/9e49679857b54972a69fef62a9f567bf
Autor:
Mayra Furlan-Magaril, Masami Ando-Kuri, Rodrigo G. Arzate-Mejía, Jörg Morf, Jonathan Cairns, Abraham Román-Figueroa, Luis Tenorio-Hernández, A. César Poot-Hernández, Simon Andrews, Csilla Várnai, Boo Virk, Steven W. Wingett, Peter Fraser
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-27 (2021)
Abstract Background Circadian gene expression is essential for organisms to adjust their physiology and anticipate daily changes in the environment. The molecular mechanisms controlling circadian gene transcription are still under investigation. In p
Externí odkaz:
https://doaj.org/article/9a210e18686b41e2bfd4786eebcb2e8a
Autor:
Rodrigo G. Arzate-Mejía, Angel Josué Cerecedo-Castillo, Georgina Guerrero, Mayra Furlan-Magaril, Félix Recillas-Targa
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
In Drosophila, transcription is thought to be required for TAD formation, while the role of architectural proteins remains controversial. Here, the authors find that deletion of domain boundaries at the fly Notch locus results in TAD fusion and long-
Externí odkaz:
https://doaj.org/article/393e8b7027a242d192e00adcd68c2093
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/06cc2c7b810d4abebd8e764b6e94f79c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Heterochromatin is a constituent of eukaryotic genomes with functions spanning from gene expression silencing to constraining DNA replication and repair. Inside the nucleus, heterochromatin segregates spatially from euchromatin and is localized prefe
Externí odkaz:
https://doaj.org/article/a7a29359bc9840a3bce9894a5d27198c
Autor:
Clara Lopes Novo, Biola-Maria Javierre, Jonathan Cairns, Anne Segonds-Pichon, Steven W. Wingett, Paula Freire-Pritchett, Mayra Furlan-Magaril, Stefan Schoenfelder, Peter Fraser, Peter J. Rugg-Gunn
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2615-2627 (2018)
Summary: Transcriptional enhancers, including super-enhancers (SEs), form physical interactions with promoters to regulate cell-type-specific gene expression. SEs are characterized by high transcription factor occupancy and large domains of active ch
Externí odkaz:
https://doaj.org/article/a9fe24befd3e4a119da1557f07e1eacc
Autor:
Tamir Chandra, Philip Andrew Ewels, Stefan Schoenfelder, Mayra Furlan-Magaril, Steven William Wingett, Kristina Kirschner, Jean-Yves Thuret, Simon Andrews, Peter Fraser, Wolf Reik
Publikováno v:
Cell Reports, Vol 10, Iss 4, Pp 471-483 (2015)
Cellular senescence has been implicated in tumor suppression, development, and aging and is accompanied by large-scale chromatin rearrangements, forming senescence-associated heterochromatic foci (SAHF). However, how the chromatin is reorganized duri
Externí odkaz:
https://doaj.org/article/3c24731ad6c0489a928431702a77252b
Autor:
Paula Freire-Pritchett, Stefan Schoenfelder, Csilla Várnai, Steven W Wingett, Jonathan Cairns, Amanda J Collier, Raquel García-Vílchez, Mayra Furlan-Magaril, Cameron S Osborne, Peter Fraser, Peter J Rugg-Gunn, Mikhail Spivakov
Publikováno v:
eLife, Vol 6 (2017)
Long-range cis-regulatory elements such as enhancers coordinate cell-specific transcriptional programmes by engaging in DNA looping interactions with target promoters. Deciphering the interplay between the promoter connectivity and activity of cis-re
Externí odkaz:
https://doaj.org/article/6b57a130ecbc478aaa570feb12bd03e6