Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mayowa A. Osundiji"'
Autor:
Jessie M. Cameron, Mayowa Azeez Osundiji, Rory J. Olson, Bukola A. Olarewaju, Andreas Schulze
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101815- (2024)
Purpose: Arginase 1 (ARG1) deficiency manifests with hyperargininemia and progressive neurological impairment. Recent estimates of birth prevalence using allele frequencies of ARG1 variants do not sufficiently distinguish benign from pathogenic varia
Externí odkaz:
https://doaj.org/article/6460798f10a846f5867f510d67f92ae2
Autor:
Tawakalitu Abosede Kehinde, Alisha Bhatia, Bukola Olarewaju, Muhammad Zain Shoaib, Jehan Mousa, Mayowa Azeez Osundiji
Publikováno v:
European journal of medical genetics. 65(3)
Obesity is a growing public health problem in many developed countries, although similar trends are increasingly being described in some developing nations. The genetic underpinnings of obesity continue to arouse increasing research interests, invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0c326103ee8763e9e9f47be749778a
https://pubmed.ncbi.nlm.nih.gov/35085835
https://pubmed.ncbi.nlm.nih.gov/35085835
Publikováno v:
European Journal of Haematology
Coronavirus Disease 2019 (COVID‐19) pandemic is a rapidly evolving public health problem. The severity of COVID‐19 cases reported hitherto has varied greatly from asymptomatic to severe pneumonia and thromboembolism with subsequent mortality. An
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063d89f4984cb3360444fcec12bdbb05
https://pubmed.ncbi.nlm.nih.gov/32589774
https://pubmed.ncbi.nlm.nih.gov/32589774
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28016 (2011)
Hypoglycemia or glucoprivation triggers protective hormonal counterregulatory and feeding responses to aid the restoration of normoglycemia. Increasing evidence suggests pertinent roles for the brain in sensing glucoprivation and mediating counterreg
Externí odkaz:
https://doaj.org/article/4876ec8713cd4698b49b4a56933acdf5
Autor:
Tao Liang, Herbert Y. Gaisano, Mladen Vranic, Ya-Chi Huang, Mark S. Cattral, Michael C. Riddell, Mayowa A. Osundiji, David H. Coy, Trevor Teich, Tairan Qin, Negar Karimian
Publikováno v:
Diabetes
Impaired counterregulation during hypoglycemia in type 1 diabetes (T1D) is partly attributable to inadequate glucagon secretion. Intra-islet somatostatin (SST) suppression of hypoglycemia-stimulated α-cell glucagon release plays an important role. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623152ddf8a726d5da06396aaa604a32
http://europepmc.org/articles/PMC3717832
http://europepmc.org/articles/PMC3717832
Autor:
Mark L. Evans, Carolina Colliva, S. Pauliina Markkula, Jill Shaw, Daniel D. Lam, Aldo Roda, Paul Hurst, Mayowa A. Osundiji, Lora K. Heisler, Chen-Yu Yueh
Publikováno v:
Diabetes
As patients decline from health to type 2 diabetes, glucose-stimulated insulin secretion (GSIS) typically becomes impaired. Although GSIS is driven predominantly by direct sensing of a rise in blood glucose by pancreatic β-cells, there is growing ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbc0525eb83ee28e0ac97fe7ac09c68d
https://doi.org/10.2337/db11-1050
https://doi.org/10.2337/db11-1050
Autor:
Ligang Zhou, Andreas Vegge, Chen-Yu Yueh, Mayowa A. Osundiji, Philip Y. Xiu, Mark L. Evans, Lora K. Heisler, Britt T. Christensen, Daniel D. Lam
Publikováno v:
Behavioural Brain Research
Pharmacological compounds enhancing serotonergic tone significantly decrease food intake and are among the most clinically efficacious treatments for obesity. However, the central mechanisms through which serotonergic compounds modulate feeding behav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e400b08f533595fe67d767d957fa5d
https://doi.org/10.1016/j.bbr.2008.07.039
https://doi.org/10.1016/j.bbr.2008.07.039
Autor:
Nika N. Danial, Gregory H. Bird, Loren D. Walensky, Benjamin Szlyk, Mayowa A. Osundiji, Elaura Patton, Sanda Ljubicic, Craig R. Braun, Franz M. Matschinsky
Glucokinase is a glucose-phosphorylating enzyme that regulates insulin release and hepatic metabolism, and its loss-of-function is implicated in the pathogenesis of diabetes. Glucokinase activators (GKAs) are attractive therapeutics in diabetes, howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3798043dc7dbd8fa288ee6f26801c5e
https://europepmc.org/articles/PMC4084830/
https://europepmc.org/articles/PMC4084830/
Autor:
Mark L. Evans, Mayowa A. Osundiji
Publikováno v:
Endocrinology and metabolism clinics of North America. 42(1)
Islet hormones, especially insulin and glucagon, are important for glucose homeostasis. Insulin is a necessity for life, and disturbed insulin release results in disordered blood glucose regulation. Although isolated islets are fully capable of detec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3438a4cb41bb7b47e27ba472138a5187
https://pubmed.ncbi.nlm.nih.gov/23391236
https://pubmed.ncbi.nlm.nih.gov/23391236
Autor:
Klaudia Polak, Sheene Kim, Jill K. Fisher, Gary W. Cline, Hu Huang, Benjamin Szlyk, Dae Ho Lee, Gerald I. Shulman, Alfredo Giménez-Cassina, Nika N. Danial, Alberto Distefano, Kirsten Robertson, Marina Godes, Muhammed A. Yildirim, Cheol Soo Choi, Ameya Kulkarni, Varman T. Samuel, Elaura Patton, Young-Bum Kim, Mayowa A. Osundiji, Luisa Garcia-Haro, Jessica Wiwczar, Elizabeth A. Lane
Publikováno v:
Cell metabolism. 19(2)
Summary The homeostatic balance of hepatic glucose utilization, storage, and production is exquisitely controlled by hormonal signals and hepatic carbon metabolism during fed and fasted states. How the liver senses extracellular glucose to cue glucos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2947ad9fc6f0b9a54911344820f1d6ae
https://pubmed.ncbi.nlm.nih.gov/24506868
https://pubmed.ncbi.nlm.nih.gov/24506868