Liver-Specific Activation of AMPK Prevents Steatosis on a High-Fructose Diet.

Autor: Woods A; MRC London Institute of Medical Sciences, Imperial College London, Hammersmith Hospital, London W12 0NN, UK. Electronic address: angela.woods@lms.mrc.ac.uk., Williams JR; MRC London Institute of Medical Sciences, Imperial College London, Hammersmith Hospital, London W12 0NN, UK., Muckett PJ; MRC London Institute of Medical Sciences, Imperial College London, Hammersmith Hospital, London W12 0NN, UK., Mayer FV; MRC London Institute of Medical Sciences, Imperial College London, Hammersmith Hospital, London W12 0NN, UK., Liljevald M; Drug Safety and Metabolism, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Pepparedsleden 1, Mölndal 431 83, Sweden., Bohlooly-Y M; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Pepparedsleden 1, Mölndal 431 83, Sweden., Carling D; MRC London Institute of Medical Sciences, Imperial College London, Hammersmith Hospital, London W12 0NN, UK; Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital, London W12 0NN, UK. Electronic address: david.carling@lms.mrc.ac.uk.

Publikováno v: Cell reports [Cell Rep] 2017 Mar 28; Vol. 18 (13), pp. 3043-3051.

Antimicrobial mitochondrial reactive oxygen species induction by lung epithelial immunometabolic modulation.

Autor: Wang, Yongxing¹ (AUTHOR), Kulkarni, Vikram V.^1,2 (AUTHOR), Pantaleón García, Jezreel¹ (AUTHOR), Leiva-Juárez, Miguel M.¹ (AUTHOR), Goldblatt, David L.¹ (AUTHOR), Gulraiz, Fahad¹ (AUTHOR), Vila Ellis, Lisandra¹ (AUTHOR), Chen, Jichao¹ (AUTHOR), Longmire, Michael K.^1,2 (AUTHOR), Donepudi, Sri Ramya³ (AUTHOR), Lorenzi, Philip L.³ (AUTHOR), Wang, Hao⁴ (AUTHOR), Wong, Lee-Jun⁴ (AUTHOR), Tuvim, Michael J.¹ (AUTHOR), Evans, Scott E.^1,2 (AUTHOR) seevans@mdanderson.org

Publikováno v: PLoS Pathogens. 9/11/2023, Vol. 19 Issue 9, p1-28. 28p.

AMP-activated protein kinase: nature's energy sensor.

Autor: Carling D; Medical Research Council (MRC) Clinical Sciences Centre, Cellular Stress Group, Hammersmith Hospital Campus, Imperial College, London, UK. dcarling@imperial.ac.uk, Mayer FV, Sanders MJ, Gamblin SJ

Publikováno v: Nature chemical biology [Nat Chem Biol] 2011 Jul 18; Vol. 7 (8), pp. 512-8. Date of Electronic Publication: 2011 Jul 18.

Modulation of AMPK/ TET2/ 5-hmC axis in response to metabolic alterations as a novel pathway for obesity-related colorectal cancer development.

Autor: Kon, Takashi¹ (AUTHOR), Sasaki, Yu¹ (AUTHOR) y-sasaki@med.id.yamagata-u.ac.jp, Abe, Yasuhiko² (AUTHOR), Onozato, Yusuke¹ (AUTHOR), Yagi, Makoto² (AUTHOR), Mizumoto, Naoko¹ (AUTHOR), Sakai, Takayuki¹ (AUTHOR), Umehara, Matsuki¹ (AUTHOR), Ito, Minami¹ (AUTHOR), Nakamura, Shuhei¹ (AUTHOR), Goto, Hiroki¹ (AUTHOR), Ueno, Yoshiyuki¹ (AUTHOR)

Publikováno v: Scientific Reports. 2/17/2023, Vol. 13 Issue 1, p1-12. 12p.

The emerging role of deubiquitylating enzymes as therapeutic targets in cancer metabolism.

Autor: Tu, Rongfu^1,2 (AUTHOR), Ma, Junpeng^1,2 (AUTHOR), Zhang, Peng^1,3 (AUTHOR), Kang, Ye^1,2 (AUTHOR), Xiong, Xiaofan⁴ (AUTHOR), Zhu, Junsheng^1,2 (AUTHOR), Li, Miao^1,2 (AUTHOR), Zhang, Chengsheng^1,2,3,5 (AUTHOR) cszhang99@xjtu.edu.cn

Publikováno v: Cancer Cell International. 11/12/2022, Vol. 22 Issue 1, p1-14. 14p.