Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Maybelline Giam"'
Autor:
Jamie Trott, Ee Kim Tan, Sheena Ong, Drew M. Titmarsh, Simon L.I.J. Denil, Maybelline Giam, Cheng Kit Wong, Jiaxu Wang, Mohammad Shboul, Michelle Eio, Justin Cooper-White, Simon M. Cool, Giulia Rancati, Lawrence W. Stanton, Bruno Reversade, N. Ray Dunn
Publikováno v:
Stem Cell Reports, Vol 8, Iss 6, Pp 1675-1688 (2017)
Pluripotent stem cells have been proposed as an unlimited source of pancreatic β cells for studying and treating diabetes. However, the long, multi-step differentiation protocols used to generate functional β cells inevitably exhibit considerable v
Externí odkaz:
https://doaj.org/article/420b4b50331549cead36ed5ee5db165a
Autor:
Kavya Prasad, Mathew Bloomfield, Hagai Levi, Kristina Keuper, Sara V. Bernhard, Nicolaas C. Baudoin, Gil Leor, Yonatan Eliezer, Maybelline Giam, Cheng Kit Wong, Giulia Rancati, Zuzana Storchová, Daniela Cimini, Uri Ben-David
Publikováno v:
Cancer Res
Aneuploidy is a hallmark of cancer with tissue-specific prevalence patterns that suggest it plays a driving role in cancer initiation and progression. However, the contribution of aneuploidy to tumorigenesis depends on both cellular and genomic conte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68879913814bc15d468354095253ac25
https://europepmc.org/articles/PMC9069772/
https://europepmc.org/articles/PMC9069772/
Autor:
Kristina Keuper, Mathew Bloomfield, Hagai Levi, Prasad K, Nicolaas C. Baudoin, Zuzana Storchova, Cheng Kit Wong, Sara Vanessa Bernhard, Uri Ben-David, Daniela Cimini, Leor G, Maybelline Giam, Giulia Rancati
Aneuploidy – a hallmark of cancer – has tissue-specific recurrence patterns suggesting it plays a driving role in cancer initiation and progression. However, the contribution of aneuploidy to tumorigenesis depends on the cellular and genomic cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08cc80b27698fa60462971c7a94cf0d7
https://doi.org/10.1101/2021.05.05.442712
https://doi.org/10.1101/2021.05.05.442712
Autor:
Suad M Abdirahman, Michelle Palmieri, Hon Yan Kelvin Yip, Oliver M. Sieber, Tracy L Putoczki, Nga Lam, Ka Yee Fung, Kristy Meiselbach, Christopher G. Love, Chin Wee Tan, Adele Preaudet, Paul M Nguyen, Maybelline Giam, Ronnie Ren Jie Low, Andrew I. Webb, Ashleigh R Poh, Laura F. Dagley, Akshay D' Cruz, Tony Burgess, Rebecca Feltham, Matthias Ernst, Yumiko Hirokawa, Charlotte Burstroem, Kaheina Aizel, Gemma van Duijneveldt, Philippe Bouillet
Publikováno v:
Cell Death and Differentiation
Gastrointestinal epithelial cells provide a selective barrier that segregates the host immune system from luminal microorganisms, thereby contributing directly to the regulation of homeostasis. We have shown that from early embryonic development Bcl-
Autor:
Simon M. Cool, Lawrence W. Stanton, Mohammad Shboul, Simon Denil, Drew M. Titmarsh, Giulia Rancati, Justin J. Cooper-White, Ee Kim Tan, Jamie Trott, Sheena Ong, Bruno Reversade, Maybelline Giam, Jiaxu Wang, Michelle Eio, N. Ray Dunn, Cheng Kit Wong
Publikováno v:
Stem Cell Reports, Vol 8, Iss 6, Pp 1675-1688 (2017)
Stem Cell Reports
Stem Cell Reports
Summary Pluripotent stem cells have been proposed as an unlimited source of pancreatic β cells for studying and treating diabetes. However, the long, multi-step differentiation protocols used to generate functional β cells inevitably exhibit consid
Publikováno v:
Cell Cycle
Aneuploidy is the condition of having an imbalanced karyotype, which is strongly associated with tumor initiation, evolution, and acquisition of drug-resistant features, possibly by generating heterogeneous populations of cells with distinct genotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19593c8894ec452f8d24284e23f3ab71
Publikováno v:
Molecules and Cells. 27:577-582
The development of a high-throughput functional genomic screening provides a novel and expeditious approach in identifying critical genes involved in specific biological processes. Here we describe a cell-based cDNA screening system to identify the t
Publikováno v:
Atlas of Genetics and Cytogenetics in Oncology and Haematology.
Review on BCL2L11 (BCL2-like 11 (apoptosis facilitator)), with data on DNA, on the protein encoded, and where the gene is implicated.
Autor:
Maybelline Giam, Owen M. Siggs, Delphine Merino, Erinna F. Lee, Klaus Heger, Peter Hughes, Philippe Bouillet, Jerry M. Adams, Andreas Strasser, W.D. Fairlie, Lorraine A. O'Reilly
Publikováno v:
The Journal of Cell Biology
Proteins of the Bcl-2 family are critical regulators of apoptosis, but how its BH3-only members activate the essential effectors Bax and Bak remains controversial. The indirect activation model suggests that they simply must neutralize all of the pro
Publikováno v:
Cell Death & Disease
The three major subgroups of the Bcl-2 family, including the prosurvival Bcl-2-like proteins, the proapoptotic Bcl-2 homology (BH)3-only proteins and Bax/Bak proteins, regulate the mitochondrial apoptotic pathway. In addition, some outliers within th