Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Mayasah Al-Nema"'
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022)
Abstract Existing medications i.e. the antipsychotic drugs are known to be effective in treating only the positive symptoms of schizophrenia, while being ineffective on negative and cognitive symptoms of the disease. In addition, these medications ca
Externí odkaz:
https://doaj.org/article/648a9daabe354670a5b0333d58b423b0
Autor:
Mayasah Al-Nema, Anand Gaurav, Ming Tatt Lee, Patrick Okechukwu, Piyarat Nimmanpipug, Vannajan Sanghiran Lee
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0278216 (2022)
Phosphodiesterase 1B (PDE1B) and PDE10A are dual-specificity PDEs that hydrolyse both cyclic adenosine monophosphate and cyclic guanosine monophosphate, and are highly expressed in the striatum. Several reports have suggested that PDE10A inhibitors m
Externí odkaz:
https://doaj.org/article/d8d620f12af64354b6500912431a3fdc
Autor:
Marwan Abdelmahmoud Abdelkarim Maki, Palanirajan Vijayaraj Kumar, Shiau-Chuen Cheah, Yeong Siew Wei, Mayasah Al-Nema, Omer Bayazeid, Abu Bakar Bin Abdul Majeed
Publikováno v:
ACS Omega, Vol 4, Iss 5, Pp 8767-8777 (2019)
Externí odkaz:
https://doaj.org/article/00beb3e5bd5a4762bfb0b8dabbb32bca
Publikováno v:
Heliyon, Vol 6, Iss 9, Pp e04856- (2020)
Inhibition of phosphodiesterase 4 (PDE4) is a promising therapeutic approach for the treatment of inflammatory pulmonary disorders, i.e. asthma and chronic obstructive pulmonary disease. However, the treatment with non-selective PDE4 inhibitors is as
Externí odkaz:
https://doaj.org/article/aa1a46c3849647e7b559446e27be02a1
Publikováno v:
Current Topics in Medicinal Chemistry. 22:2190-2206
Abstract: Over the last two decades computational technologies have always played a crucial role in anti-viral drug development. Whenever a virus spreads and becomes a threat to global health it brings along the challenge to develop new therapeutics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166b0ab669d6fee16350d4ad6d8cd2b4
https://doi.org/10.2174/1568026623666221019110334
https://doi.org/10.2174/1568026623666221019110334
Autor:
Mayasah Al-Nema, Anand Gaurav
Publikováno v:
Jordan Journal of Pharmaceutical Sciences. 15:239-257
Background: Schizophrenia is considered one of the top 10 conditions that cause disability worldwide. Regardless of its low prevalence, it negatively impacts the quality of life not only for patients but also for families and society. The present ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db212da4bf78551f377f5c96c9538400
https://doi.org/10.35516/jjps.v15i2.323
https://doi.org/10.35516/jjps.v15i2.323
Autor:
Mayasah Al-Nema, Anand Gaurav, Vannajan Sanghiran Lee, Baskaran Gunasekaran, Ming Tatt Lee, Patrick Okechukwu, Piyarat Nimmanpipug
Publikováno v:
RSC Advances. 12:1576-1591
Phosphodiesterase10A (PDE10A) is a potential therapeutic target for the treatment of several neurodegenerative disorders.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a3ee46aff1b3a1e40966908fb8d6a60
https://doi.org/10.1039/d1ra07649c
https://doi.org/10.1039/d1ra07649c
Publikováno v:
Computers in Biology and Medicine. 159:106869
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01e59c8774d5768764326b0fc7a47178
https://doi.org/10.1016/j.compbiomed.2023.106869
https://doi.org/10.1016/j.compbiomed.2023.106869
Autor:
Anand Gaurav, Mayasah Al-Nema
Publikováno v:
Current Topics in Medicinal Chemistry. 20:2404-2421
Schizophrenia is a severe mental disorder that affects more than 1% of the population worldwide. Dopamine system dysfunction and alterations in glutamatergic neurotransmission are strongly implicated in the aetiology of schizophrenia. To date, antips
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6774bb465c5bda916be2ef7dc7c240c0
https://doi.org/10.2174/1568026620666200613202641
https://doi.org/10.2174/1568026620666200613202641
Publikováno v:
Current Trends in Biotechnology and Pharmacy. 14:1-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6c0516e3fb65180d67c0e8b48f54a99
https://doi.org/10.5530/ctbp.2020.4s.1
https://doi.org/10.5530/ctbp.2020.4s.1