Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mayara Grizotte-Lake"'
Autor:
Ge Yang, Mohammad Massumi, Shahryar Khoshtinat Nikkhoi, Hajar Owji, Mayara Grizotte-Lake, Rick I Cohen, Lazaro Gil Gonzalez, Arash Hatefi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 3 (2024)
Background In a prior report, we detailed the isolation and engineering of a bispecific killer cell engager, referred to as BiKE:E5C1. The BiKE:E5C1 exhibits high affinity/specificity for the CD16a activating receptor on natural killer (NK) cells and
Externí odkaz:
https://doaj.org/article/155b517c70c74416a35702828b6d5b6c
Autor:
Leonard Moise, Lauren M. Meyers, Hyesun Jang, Mayara Grizotte-Lake, Christine M. Boyle, Bethany McGonnigal, Pan Ge, Ted M. Ross, Anne S. De Groot
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 18, Iss 4 (2022)
Strategies that improve influenza vaccine immunogenicity are critical for the development of vaccines for pandemic preparedness. Hemagglutinin (HA)-specific CD4+ T cell epitopes support protective B cell responses against seasonal influenza. However,
Externí odkaz:
https://doaj.org/article/c0c0dd6971c34458b782b56c5cbec279
Autor:
Namrata Iyer, Mayara Grizotte-Lake, Kellyanne Duncan, Sarah R Gordon, Ana C S Palmer, Crystle Calvin, Guo Zhong, Nina Isoherranen, Shipra Vaishnava
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008360 (2020)
Intestinal epithelial cells (IECs) are at the forefront of host-pathogen interactions, coordinating a cascade of immune responses to protect against pathogens. Here we show that IEC-intrinsic vitamin A signaling restricts pathogen invasion early in t
Externí odkaz:
https://doaj.org/article/6b97c72352b24670a9a3d5135e87153e
Autor:
Ana C. S. Palmer, Namrata Iyer, Crystle Calvin, Mayara Grizotte-Lake, Sarah R. Gordon, Shipra Vaishnava
Intestinal epithelial cells (IECs) are at the forefront of host-pathogen interactions, coordinating a cascade of immune responses to confer protection against pathogens. Here we show that IEC-intrinsic vitamin A signaling restricts pathogen invasion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5fedb8c9ebfd772d4ffb4955dfebeb
Autor:
Guo Zhong, Mayara Grizotte-Lake, Shipra Vaishnava, Sarah R. Gordon, Crystle Calvin, Namrata Iyer, Nina Isoherranen, Ana C. S. Palmer, Kellyanne Duncan
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 4, p e1008360 (2020)
PLoS Pathogens, Vol 16, Iss 4, p e1008360 (2020)
Intestinal epithelial cells (IECs) are at the forefront of host-pathogen interactions, coordinating a cascade of immune responses to protect against pathogens. Here we show that IEC-intrinsic vitamin A signaling restricts pathogen invasion early in t
Autor:
Shipra Vaishnava, Mayara Grizotte-Lake
Publikováno v:
Cell Host & Microbe. 23:147-148
Autophagy is genetically associated with inflammatory bowel disease (IBD); however, its role remains unclear in disease pathogenesis. Three recent studies reveal a novel cytoprotective role of autophagy during viral, bacterial, and protozoan-triggere
Autor:
Kellyanne Duncan, Jay S. Kirkwood, Namrata Iyer, Guo Zhong, Irina Smolenski, Mayara Grizotte-Lake, Nina Isoherranen, Shipra Vaishnava
Publikováno v:
Immunity. 49:1103-1115.e6
Retinoic acid (RA), a vitamin A metabolite, regulates transcriptional programs that drive protective or pathogenic immune responses in the intestine, in a manner dependent on RA concentration. Vitamin A is obtained from diet and is metabolized by int
Autor:
Mayara Grizotte-Lake, Shipra Vaishnava
Publikováno v:
The Journal of Immunology. 200:170.21-170.21
Antimicrobials secreted by the intestinal epithelium are critical for regulating host-microbe interactions in the gut. However, certain pathogens can exploit excessive antimicrobial response during infection to outcompete commensal bacteria. We have
Autor:
Gideon Koren, Yukiko Kunitomo, Xuwen Peng, Tae Yun Kim, Joseph F. Yammine, Bum-Rak Choi, Yichun Lu, Jean M. Daley, Kamana Bist, Lorraine Schofield, Mayara Grizotte-Lake, Zhilin Qu
Publikováno v:
Biophysical Journal. 108(2)
Background: Patients with post myocardial infarction (MI) have increased incidence of ventricular arrhythmias. The slowly activating K+ channels (IKs) has been reported to be downregulated consistently but in different degrees in the post-MI hearts.