Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mayara Barbalho Félix"'
Autor:
Jéssika de Oliveira Viana, Mayara Barbalho Félix, Mayara dos Santos Maia, Vanessa de Lima Serafim, Luciana Scotti, Marcus Tullius Scotti
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 54, Iss spe (2018)
The pharmaceutical industry is increasingly joining chemoinformatics in the search for the development of new drugs to be used in the treatment of diseases. These computational studies have the advantage of being less expensive and optimize the study
Externí odkaz:
https://doaj.org/article/e5ed8b0ffbe246788c7302e7ba46c9c5
Autor:
Carlos A. de Simone, Renata Priscila Costa Barros, Thaís Amanda de Lima Nunes, Marcus Tullius Scotti, Rodrigo Santos Aquino de Araújo, Francisco Jaime Bezerra Mendonça Junior, Mayara Barbalho Félix, Eugene N. Muratov, Raiza Raianne Luz Rodrigues, Klinger Antonio da Franca Rodrigues, Luciana Scotti
Publikováno v:
Current Topics in Medicinal Chemistry. 20:1704-1719
Background: Chemoinformatics has several applications in the field of drug design, helping to identify new compounds against a range of ailments. Among these are Leishmaniasis, effective treatments for which are currently limited. Objective: To const
Autor:
Francisco Allysson Assis Ferreira Gadelha, Margareth de Fátima Formiga Melo Diniz, Mateus Feitosa Alves, Marcus Tullius Scotti, Luciana Scotti, Kardilândia Mendes de Oliveira, Mayara Barbalho Félix, Larissa A.M. Paiva Ferreira, Laércia Karla Diega Paiva Ferreira, Sócrates Golzio dos Santos
Publikováno v:
Natural product research. 33(6)
The ethanolic extract of the leaves of Cissampelos sympodialis showed great pharmacological potential, with inflammatory and immunomodulatory activities, however, it showed some toxicological effects. Therefore, this study aims to verify the toxicolo
Autor:
Ricardo Olímpio de Moura, Klinger Antonio da Franca Rodrigues, Patrícia Néris Andrade, Maria do Carmo Alves de Lima, Mayara Barbalho Félix, Márcia Rosa de Oliveira, Daiana Karla Frade Silva, Sinara Mônica Vitalino de Almeida, Jamerson Ferreira de Oliveira, Marcus Tullius Scotti, Francisco Jaime Bezerra Mendonça-Junior, Sanderssonilo de Albuquerque dos Santos, Vanessa de Lima Serafim
Publikováno v:
Chemical biologydrug design. 91(6)
In this study, we synthesized eight new compounds containing the 2-amino-cycloalkyl[b]thiophene and acridine moieties (ACT01 and ACS01 -ACS07 ). None tested compounds presented human erythrocyte cytotoxicity. The new compounds presented antipromastig
Autor:
Marcus Tullius Scotti, Élida Batista Vieira Sousa Cavalcanti, Mayara Barbalho Félix, Luciana Scotti
Publikováno v:
Anti-cancer agents in medicinal chemistry. 19(2)
Cancer is the main cause of death, so the search for active agents to be used in the therapy of this disease, is necessary. According to studies conducted, substances derived from natural products have shown to be promising in this endeavor. To these
Autor:
Mayara Barbalho Félix, Mateus Feitosa Alves, Frederico Fávaro Ribeiro, Alexandre Rolim da Paz, Margareth de Fátima Formiga Melo Diniz, Marcus Tullius Scotti, Cinthia Rodrigues Melo, Kardilândia Mendes de Oliveira, Hamilton Mitsugu Ishiki, Luciana Scotti, Francisco Jaime Bezerra Mendonça, Andrea Fernanda Ramos de Paula, José Maria Barbosa Filho, Josean Fechine Tavares, Sócrates Golzio dos Santos
Publikováno v:
Current drug metabolism. 18(6)
Cissampelos sympodialis is a plant in northeastern Brazil used by the populace for treating respiratory diseases. Several studies have shown that ethanol leaf extracts have immunomodulatory and anti-inflammatory activities. Infusions are widely used,
Autor:
Daiana Karla G. Frade, Mayara Barbalho Félix, Marcus Tullius Scotti, Luciana Scotti, Vanessa de Lima Serafim, Francisco Jaime Bezerra Mendonça Junior, Márcia Rosa de Oliveira, Thiago Mendonça de Aquino, Maria do Carmo Alves de Lima, Frederico Fávaro Ribeiro, Klinger Antonio da Franca Rodrigues, Patrícia Lima do Nascimento Néris, Edson Rubhens de Souza
Publikováno v:
Bioorganicmedicinal chemistry. 24(18)
In the present work, thirty-two hybrid compounds containing cycloalka[b]thiophene and indole moieties (TN5, TN5 1-7, TN6, TN6 1-7, TN7, TN7 1-7, TN8, TN8 1-7) were designed, synthesized and evaluated for their cytotoxic and antileishmanial activity a