Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mayar Allam"'
Autor:
Thomas Hu, Mayar Allam, Shuangyi Cai, Walter Henderson, Brian Yueh, Aybuke Garipcan, Anton V. Ievlev, Maryam Afkarian, Semir Beyaz, Ahmet F. Coskun
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Metabolic reprogramming in cancer and immune cells occurs to support their increasing energy needs in biological tissues. Here we propose Single Cell Spatially resolved Metabolic (scSpaMet) framework for joint protein-metabolite profiling of
Externí odkaz:
https://doaj.org/article/005c3c264bfd4983a199d821ea1bd797
Autor:
Mayar Allam, Thomas Hu, Jeongjin Lee, Jeffrey Aldrich, Sunil S. Badve, Yesim Gökmen-Polar, Manali Bhave, Suresh S. Ramalingam, Frank Schneider, Ahmet F. Coskun
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-21 (2022)
Abstract The Immunoscore is a method to quantify the immune cell infiltration within cancers to predict the disease prognosis. Previous immune profiling approaches relied on limited immune markers to establish patients’ tumor immunity. However, imm
Externí odkaz:
https://doaj.org/article/9e5070068683451ebbd1a83b5eb66b7b
Autor:
Shuangyi Cai, Thomas Hu, Mythreye Venkatesan, Mayar Allam, Frank Schneider, Suresh S. Ramalingam, Shi-Yong Sun, Ahmet F. Coskun
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104980- (2022)
Summary: Protein-protein interaction networks are altered in multi-gene dysregulations in many disorders. Image-based protein multiplexing sheds light on signaling pathways to dissect cell-to-cell heterogeneity, previously masked by the bulk assays.
Externí odkaz:
https://doaj.org/article/2973f78274a64a138c9d983aadb5dd2c
Autor:
Mayar Allam, Thomas Hu, Shuangyi Cai, Krishnan Laxminarayanan, Robert B. Hughley, Ahmet F. Coskun
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Allam, Hu, et al. present SpatialViz, a suite of algorithms to explore spatial relationships in multiplexed tissue images by visualizing and quantifying single-cell granularity and anatomical complexity in diverse multiplexed tissue imaging data. The
Externí odkaz:
https://doaj.org/article/58ad3fe1ce344e29a65c37672e679c0a
Autor:
Mayar Allam, Shuangyi Cai, Shambavi Ganesh, Mythreye Venkatesan, Saurabh Doodhwala, Zexing Song, Thomas Hu, Aditi Kumar, Jeremy Heit, COVID-19 Study Group, Ahmet F. Coskun
Publikováno v:
Diagnostics, Vol 10, Iss 6, p 409 (2020)
The Coronavirus Disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), outbreak from Wuhan City, Hubei province, China in 2019 has become an ongoing global health emergency. The emerging virus, SARS-CoV-2
Externí odkaz:
https://doaj.org/article/819b10617cbc4d8c8be9d88ffa5dc5e5
Autor:
Shivem B. Shah, Christopher R. Carlson, Kristine Lai, Zhe Zhong, Grazia Marsico, Katherine M. Lee, Nicole E. Félix Vélez, Elisabeth B. Abeles, Mayar Allam, Thomas Hu, Lauren D. Walter, Karen E. Martin, Khanjan Gandhi, Scott D. Butler, Rishi Puri, Angela L. McCleary-Wheeler, Wayne Tam, Olivier Elemento, Katsuyoshi Takata, Christian Steidl, David W. Scott, Lorena Fontan, Hideki Ueno, Benjamin D. Cosgrove, Giorgio Inghirami, Andrés J. García, Ahmet F. Coskun, Jean L. Koff, Ari Melnick, Ankur Singh
Publikováno v:
Nature Materials. 22:511-523
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::437c365c91fd56ca70ff4d85310517bf
https://doi.org/10.1038/s41563-023-01495-3
https://doi.org/10.1038/s41563-023-01495-3
Autor:
Aditi Kumar, Shuangyi Cai, Mayar Allam, Samuel Henderson, Melissa Ozbeyler, Lilly Saiontz, Ahmet F. Coskun
Publikováno v:
Cancer Systems and Integrative Biology ISBN: 9781071631621
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5a669da4175b77769ea6742fb041abc
https://doi.org/10.1007/978-1-0716-3163-8_22
https://doi.org/10.1007/978-1-0716-3163-8_22
Autor:
Alexandra Zamitalo, Qingtong Xie, Mayar Allam, Phinu Philip, Wenqi Shi, Felipe Giuste, Benoit Marteau, Mio Murakoso, May D. Wang
Publikováno v:
2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::410be7122d5dba51d238e917d44c976a
https://doi.org/10.1109/bibm55620.2022.9995319
https://doi.org/10.1109/bibm55620.2022.9995319
Autor:
Shuangyi Cai, Thomas Hu, Mythreye Venkatesan, Mayar Allam, Frank Schneider, Suresh S. Ramalingam, Shi-Yong Sun, Ahmet F. Coskun
Publikováno v:
iScience. 25(9)
Protein-protein interaction networks are altered in multi-gene dysregulations in many disorders. Image-based protein multiplexing sheds light on signaling pathways to dissect cell-to-cell heterogeneity, previously masked by the bulk assays. Herein, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce2fc31708f741cfdde37642aa82327
https://pubmed.ncbi.nlm.nih.gov/36093051
https://pubmed.ncbi.nlm.nih.gov/36093051
Autor:
Ahmet F. Coskun, Mayar Allam, Robert B. Hughley, Thomas Hu, Krishnan Laxminarayanan, Shuangyi Cai
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Deep molecular profiling of biological tissues is an indicator of health and disease. We used imaging mass cytometry (IMC) to acquire spatially resolved 20-plex protein data in tissue sections from normal and chronic tonsillitis cases. We present Spa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09897ebed1178451ef915f9ce374e638
https://pubmed.ncbi.nlm.nih.gov/34045665
https://pubmed.ncbi.nlm.nih.gov/34045665