Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Mayank Bhavsar"'
Autor:
Syed M. Ali, Chris Brassard, Audra Dalton, Darin Kizer, Jean-Marc Lapierre, Yanbin Liu, Magdi Moussa, Rocio Palma, Manish Tandon, David Vensel, Erika Volckova, Jianqiang Wang, Neil Westlund, Hui Wu, Rui-Yang Yang, Craig Bates, Mayank Bhavsar, Cathy Bull, Sudharshan Eathiraj, Robert Nicewonger, Ron Savage, Carol Waghorne, Jennifer Castro, Enkeleda Nakuci, Chang-Rung Chen, Dennis S. France, Thomas C.K. Chan, Mark A. Ashwell
Publikováno v:
Cancer Research. 72:3905-3905
Utilization of hydrophobic motifs present in auto-inhibited protein kinases has resulted in the identification of a series of 5,6-dihydrobenzo [h]quinazolin-2-amines with activity as fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3f2f570d6e9677ed33340d22c18292f
https://doi.org/10.1158/1538-7445.am2012-3905
https://doi.org/10.1158/1538-7445.am2012-3905
Autor:
Chang-Rung Chen, Syed Ali, Rocio Palma, Sudharshan Eathiraj, Craig Bates, Mayank Bhavsar, Chris Brassard, Jennifer O. Brown, Cathy Bull, Li Huang, Darin Kizer, Yanbin Liu, Denise McSweeney, Magdi Moussa, Enkeleda Nakuci, Manish Tandon, Dave Vensel, Erika Volckova, Jianqiang Wang, Neil Westlund, Hui Wu, Rui-Yang Yang, Dennis S. France, Mark A. Ashwell, Thomas C.K Chan
Publikováno v:
Molecular Cancer Therapeutics. 8:A139-A139
Dysregulation of members of the FGFR tyrosine kinase family has been increasingly implicated in a number of human cancers, including gastric, breast, endometrial, and bladder carcinomas. A proprietary structure-based design paradigm was employed to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af8e142c6f693f42ce27b7f0ae548025
https://doi.org/10.1158/1535-7163.targ-09-a139
https://doi.org/10.1158/1535-7163.targ-09-a139