Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Mayakonda N Palgunachari"'
Autor:
Oleg F Sharifov, Xin Xu, Amit Gaggar, William E Grizzle, Vinod K Mishra, Jaideep Honavar, Silvio H Litovsky, Mayakonda N Palgunachari, C Roger White, G M Anantharamaiah, Himanshu Gupta
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64486 (2013)
Acute respiratory distress syndrome (ARDS) due to sepsis has a high mortality rate with limited treatment options. High density lipoprotein (HDL) exerts innate protective effects in systemic inflammation. However, its role in ARDS has not been well s
Externí odkaz:
https://doaj.org/article/5461a5833a704ef29fe2545e505f5d77
Autor:
G.M. Anantharamaiah, David W. Garber, Dennis Goldberg, Eric Morrel, Geeta Datta, Mayakonda N. Palgunachari, Thomas C. Register, Susan E. Appt, C. Roger White
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 11, Pp 2075-2083 (2018)
Ac-hE18A-NH2 is a dual-domain apoE mimetic peptide that possesses the putative receptor binding domain from apoE (LRKLRKRLLR, denoted hE; residues 141–150) covalently attached to lipid-associating peptide 18A. Like apoE, Ac-hE18A-NH2 reduces plasma
Externí odkaz:
https://doaj.org/article/3f884e75404b453fa3fcb3632c8fa0ef
Autor:
C. Roger White, Geeta Datta, Amanda K.W. Buck, Manjula Chaddha, Gautam Reddy, Landon Wilson, Mayakonda N. Palgunachari, Mohammad Abbasi, G.M. Anantharamaiah
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 8, Pp 1576-1587 (2012)
Myeloperoxidase (MPO)-derived hypochlorous acid induces changes in HDL function via redox modifications at the level of apolipoprotein A-I (apoA-I). As 4F and apoA-I share structural and functional properties, we tested the hypothesis that 4F acts as
Externí odkaz:
https://doaj.org/article/d3b3d7f7caf34664a9143265b9abee99
Autor:
Gaurav Nayyar, Vinod K. Mishra, Shaila P. Handattu, Mayakonda N. Palgunachari, Ronald Shin, David T. McPherson, Champion C.S. Deivanayagam, David W. Garber, Jere P. Segrest, G.M. Anantharamaiah
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 5, Pp 849-858 (2012)
To test the hypothesis that sidedness of interfacial arginine (Arg) in apoA-I mimetic peptides, similar to that observed in apoA-I (Bashtovyy, D. et al. 2011. Sequence conservation of apolipoprotein A-I affords novel insights into HDL structure-funct
Externí odkaz:
https://doaj.org/article/5936edca462f48c0a9aee53835e04f1e
Autor:
Shaila P. Handattu, Geeta Datta, Richard M. Epand, Raquel F. Epand, Mayakonda N. Palgunachari, Vinod K. Mishra, Candyce E. Monroe, Tamara D. Keenum, Manjula Chaddha, G.M. Anantharamaiah, David W. Garber
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 12, Pp 3491-3499 (2010)
We have shown that Ac-hE18A-NH2, a dual-domain cationic apolipoprotein-mimetic peptide, reduces plasma cholesterol levels in dyslipidemic mice. Two single-domain cationic peptides based on the lytic class L peptide 18L were developed to test the hypo
Externí odkaz:
https://doaj.org/article/b2cd1a82983042aa82673a20cdf072b7
Autor:
Mohamad Navab, Piotr Ruchala, Alan J. Waring, Robert I. Lehrer, Susan Hama, Greg Hough, Mayakonda N. Palgunachari, G.M. Anantharamaiah, Alan M. Fogelman
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 8, Pp 1538-1547 (2009)
Administered subcutaneously, D-4F or L-4F are equally efficacious, but only D-4F is orally efficacious because of digestion of L-4F by gut proteases. Orally administering niclosamide (a chlorinated salicylanilide used as a molluscicide, antihelminthi
Externí odkaz:
https://doaj.org/article/662f7eb0869c4a70b8dd9dcda249eae5
Autor:
Shaila P. Handattu, David W. Garber, Candyce E. Monroe, Thomas van Groen, Inga Kadish, Gaurav Nayyar, Dongfeng Cao, Mayakonda N. Palgunachari, Ling Li, G.M. Anantharamaiah
Publikováno v:
Neurobiology of Disease, Vol 34, Iss 3, Pp 525-534 (2009)
Recent evidence indicates that inflammation may significantly contribute to the pathogenesis of Alzheimer's disease (AD). Since the apo A-I mimetic peptide D-4F has been shown to inhibit atherosclerotic lesion formation and regress already existing l
Externí odkaz:
https://doaj.org/article/57c3d17fcb0844e4aec9796307332392
Autor:
G.M. Anantharamaiah, Vinod K. Mishra, David W. Garber, Geeta Datta, Shaila P. Handattu, Mayakonda N. Palgunachari, Manjula Chaddha, Mohamad Navab, Srinivasa T. Reddy, Jere P. Segrest, Alan M. Fogelman
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 9, Pp 1915-1923 (2007)
Recently, attention has been focused on pharmacological treatments that increase HDL cholesterol to prevent coronary artery disease. Despite three decades of extensive research of human apolipoprotein A-I (apoA-I), the major protein component of HDL,
Externí odkaz:
https://doaj.org/article/581bbdd6d38a43a4a2f6d2a91c020cd8
Autor:
Mayakonda N. Palgunachari, Geeta Datta, Gattadahalli M. Anantharamaiah, C. Roger White, Landon Wilson
Publikováno v:
Chemistry and Physics of Lipids. 219:28-35
High density lipoprotein (HDL) is prone to modification by the oxidizing and chlorinating agent hypochlorite anion (OCl(−)). Oxidation of apolipoprotein (apo) A-I, the major protein in HDL, reduces ABCA-1 mediated cholesterol efflux and other prote
Autor:
Susan E. Appt, Eric M. Morrel, Geeta Datta, David W. Garber, Dennis I. Goldberg, Mayakonda N. Palgunachari, C. Roger White, Gattadahalli M. Anantharamaiah, Thomas C. Register
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 11, Pp 2075-2083 (2018)
Journal of Lipid Research
Journal of Lipid Research
Ac-hE18A-NH2 is a dual-domain apoE mimetic peptide that possesses the putative receptor binding domain from apoE (LRKLRKRLLR, denoted hE; residues 141–150) covalently attached to lipid-associating peptide 18A. Like apoE, Ac-hE18A-NH2 reduces plasma