Zobrazeno 1 - 10
of 557
pro vyhledávání: '"Mayakonda, A"'
Autor:
Zaremba, Anne, Jansen, Philipp, Murali, Rajmohan, Mayakonda, Anand, Riedel, Anna, Krahl, Dieter, Burkhardt, Hans, John, Stefan, Géraud, Cyrill, Philip, Manuel, Kretz, Julia, Möller, Inga, Stadtler, Nadine, Sucker, Antje, Paschen, Annette, Ugurel, Selma, Zimmer, Lisa, Livingstone, Elisabeth, Horn, Susanne, Plass, Christoph, Schadendorf, Dirk, Hadaschik, Eva, Lutsik, Pavlo, Griewank, Klaus
Melanocytic neoplasms have been genetically characterized in detail during the last decade. Recurrent CTNNB1 exon 3 mutations have been recognized in the distinct group of melanocytic tumors showing deep penetrating nevus-like morphology. In addition
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A88454
https://ul.qucosa.de/api/qucosa%3A88454/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A88454/attachment/ATT-0/
Autor:
Charlotte Smith, Ashish Goyal, Dieter Weichenhan, Eric Allemand, Anand Mayakonda, Umut Toprak, Anna Riedel, Estelle Balducci, Manisha Manojkumar, Anastasija Pejkovska, Oliver Mücke, Etienne Sollier, Ali Bakr, Kersten Breuer, Pavlo Lutsik, Olivier Hermine, Salvatore Spicuglia, Vahid Asnafi, Christoph Plass, Aurore Touzart
Publikováno v:
Haematologica, Vol 108, Iss 5 (2023)
T-cell acute lymphocytic leukemia protein 1 (TAL1) is one of the most frequently deregulated oncogenes in T-cell acute lymphoblastic leukemia (T-ALL). Its deregulation can occur through diverse cis-alterations, including SIL-TAL1 microdeletions, tran
Externí odkaz:
https://doaj.org/article/6e9c05fc1a7f4ebda3d21c7b4a8a919f
Autor:
Pavlo Lutsik, Annika Baude, Daniela Mancarella, Simin Öz, Alexander Kühn, Reka Toth, Joschka Hey, Umut H. Toprak, Jinyeong Lim, Viet Ha Nguyen, Chao Jiang, Anand Mayakonda, Mark Hartmann, Felix Rosemann, Kersten Breuer, Dominik Vonficht, Florian Grünschläger, Suman Lee, Maren Kirstin Schuhmacher, Denis Kusevic, Anna Jauch, Dieter Weichenhan, Jozef Zustin, Matthias Schlesner, Simon Haas, Joo Hyun Park, Yoon Jung Park, Udo Oppermann, Albert Jeltsch, Florian Haller, Jörg Fellenberg, Anders M. Lindroth, Christoph Plass
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The histone variant mutation H3.3-G34W occurs in the majority of giant cell tumor of bone (GCTB). By profiling patient-derived GCTB tumor cells, the authors show that this mutation associates with epigenetic alterations in heterochromatic and bivalen
Externí odkaz:
https://doaj.org/article/0ca3a08070bf40f2a72b5ae76155d70a
Autor:
Deepti Talwar, Colin G. Miller, Justus Grossmann, Lukasz Szyrwiel, Torsten Schwecke, Vadim Demichev, Ana-Matea Mikecin Drazic, Anand Mayakonda, Pavlo Lutsik, Carmen Veith, Michael D. Milsom, Karin Müller-Decker, Michael Mülleder, Markus Ralser, Tobias P. Dick
Publikováno v:
Nature Metabolism. 5:660-676
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is known to contain an active-site cysteine residue undergoing oxidation in response to hydrogen peroxide, leading to rapid inactivation of the enzyme. Here we show that human and mouse cells expressin
Autor:
Anne Zaremba, Philipp Jansen, Rajmohan Murali, Anand Mayakonda, Anna Riedel, Dieter Krahl, Hans Burkhardt, Stefan John, Cyrill Géraud, Manuel Philip, Julia Kretz, Inga Möller, Nadine Stadtler, Antje Sucker, Annette Paschen, Selma Ugurel, Lisa Zimmer, Elisabeth Livingstone, Susanne Horn, Christoph Plass, Dirk Schadendorf, Eva Hadaschik, Pavlo Lutsik, Klaus Griewank
Publikováno v:
Cancers, Vol 14, Iss 17, p 4066 (2022)
Melanocytic neoplasms have been genetically characterized in detail during the last decade. Recurrent CTNNB1 exon 3 mutations have been recognized in the distinct group of melanocytic tumors showing deep penetrating nevus-like morphology. In addition
Externí odkaz:
https://doaj.org/article/0d7107597adf4e37ba6c96e105addfcc
Autor:
Ye Chen, Liang Xu, Anand Mayakonda, Mo-Li Huang, Deepika Kanojia, Tuan Zea Tan, Pushkar Dakle, Ruby Yu-Tong Lin, Xin-Yu Ke, Jonathan W. Said, Jianxiang Chen, Sigal Gery, Ling-Wen Ding, Yan-Yi Jiang, Angela Pang, Mark Edward Puhaindran, Boon Cher Goh, H. Phillip Koeffler
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Liposarcoma (LPS) is a rare cancer that can acquire resistance to chemotherapy. Here, the authors map super-enhancers in LPS, finding BET-protein dependent mechanisms that can be targeted by a BET protein degrader, which also can overcome acquired re
Externí odkaz:
https://doaj.org/article/737f0325add94122b8c3c1a96fabd32f
Autor:
Xu, Liang, Chen, Ye, Mayakonda, Anand, Koh, Lynnette, Chong, Yuk Kien, Buckley, Dennis L., Sandanaraj, Edwin, Lim, See Wee, Lin, Ruby Yu-Tong, Ke, Xin-Yu, Huang, Mo-Li, Chen, Jianxiang, Sun, Wendi, Wang, Ling-Zhi, Goh, Boon Cher, Dinh, Huy Q., Kappei, Dennis, Winter, Georg E., Ding, Ling-Wen, Ang, Beng Ti, Berman, Benjamin P., Bradner, James E., Tang, Carol, Koeffler, H. Phillip
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 May . 115(22), E5086-E5095.
Externí odkaz:
https://www.jstor.org/stable/26509954
Autor:
G.M. Anantharamaiah, David W. Garber, Dennis Goldberg, Eric Morrel, Geeta Datta, Mayakonda N. Palgunachari, Thomas C. Register, Susan E. Appt, C. Roger White
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 11, Pp 2075-2083 (2018)
Ac-hE18A-NH2 is a dual-domain apoE mimetic peptide that possesses the putative receptor binding domain from apoE (LRKLRKRLLR, denoted hE; residues 141–150) covalently attached to lipid-associating peptide 18A. Like apoE, Ac-hE18A-NH2 reduces plasma
Externí odkaz:
https://doaj.org/article/3f884e75404b453fa3fcb3632c8fa0ef
Autor:
Kar-Tong Tan, Ling-Wen Ding, Qiao-Yang Sun, Zhen-Tang Lao, Wenwen Chien, Xi Ren, Jin-Fen Xiao, Xin Yi Loh, Liang Xu, Michael Lill, Anand Mayakonda, De-Chen Lin, Henry Yang, H. Phillip Koeffler
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)
Abstract Background Clonal VDJ rearrangement of B/T cell receptors (B/TCRs) occurring during B/T lymphocyte development has been used as a marker to track the clonality of B/T cell populations. Methods We systematically profiled the B/T cell receptor
Externí odkaz:
https://doaj.org/article/ab73d11ede72491d9a1d5693f9503c26
Autor:
Xie, Jian-Jun, Jiang, Yan-Yi, Jiang, Yuan, Li, Chun-Quan, Lim, Mei-Chee, An, Omer, Mayakonda, Anand, Ding, Ling-Wen, Long, Lin, Sun, Chun, Lin, Le-Hang, Chen, Li, Wu, Jian-Yi, Wu, Zhi-Yong, Cao, Qi, Fang, Wang-Kai, Yang, Wei, Soukiasian, Harmik, Meltzer, Stephen J., Yang, Henry, Fullwood, Melissa, Xu, Li-Yan, Li, En-Min, Lin, De-Chen, Koeffler, H. Phillip
Publikováno v:
In Gastroenterology June 2018 154(8):2137-2151