Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mayako Tada"'
Autor:
Yusuke Suzuki, Mayako Tada, Ryuta Enokida, Jiro Takagi, Yoshikazu Araki, Sanjay Pareek, Sanghun Lee, Kohju Ikago, Jia Guo, Kshitij C. Shrestha, Iori Fukuda, Takeshi Masui
Publikováno v:
Frontiers in Built Environment, Vol 10 (2024)
This paper studied the feasibility of a sliding base isolation layer to be used in rubble stone masonry buildings in rural areas in the Himalayan Mountain range to provide robust protection to important building like schools against strong earthquake
Externí odkaz:
https://doaj.org/article/cd5b7c4961434e638e39b33f74e5f3b7
Autor:
Makoto Hirata, Akifumi Matsuyama, Ryuichi Sakate, Ichiro Takahashi, Toru Masui, Yosuke Kameoka, Arihiro Kohara, Mitsuho Sasaki, Mayako Tada
Publikováno v:
Human Cell. 31:183-188
Research on rare diseases cannot be performed without appropriate samples from patients with such diseases. Due to the limited number of such patients, securing biosamples of sufficient quality for extensive research is a challenge and represents an
Publikováno v:
Journal of Translational Science. 3
Autor:
Shosuke Okamoto, Yoshio Okada, Yuko Tsuda, Utako Okamoto, Mayako Tada, Keiko Wanaka, Akiko Hijikata-Okunomiya
Publikováno v:
Chemical and Pharmaceutical Bulletin. 49:1457-1463
Based on the structure of Tra-Tyr(O-Pic)-octylamide, a portion of the octylamine was replaced with moieties bearing hydrophobic, basic or acidic groups. Replacement of the C-terminal residue with a moiety bearing a hydrophobic group gave the proper a
Autor:
Akiko Hijikata-Okunomiya, Yoshio Okada, Mayako Tada, Atsuko Fukumizu, Keiko Wanaka, Yoko Tsuda, Shosuke Okamoto
Publikováno v:
Chemical and Pharmaceutical Bulletin. 47:1141-1144
Pseudo-peptide analogs of trans-4-aminomethylcyclohexanecarbonyl-L-phenylalanyl-4-aminopheny l acetic acid (PKSI-527, plasma kallikrein selective inhibitor), in which an amide bond (peptide bond) has been replaced by a CH2-NH bond, i.e., trans-4-amin
Autor:
Yoshio Okada, Shosuke Okamoto, Yuko Tsuda, Utako Okamoto, Mayako Tada, Akiko Hijikata-Okunomiya, Keiko Wanaka
Publikováno v:
Biopolymers. 51:41-50
During the course of the development of active center-directed plasmin inhibitors, it was found that N-(trans-4-aminomethylcyclohexanecarbonyl)-lysine-4-methoxycarbonylanilide inhibited plasma kallikrein more potently than other enzymes such as plasm
Autor:
Keiko Wanaka, Yuko Tsuda, Akiko Hijikata-Okunomiya, Noburo Horie, Yoshio Okada, Utako Okamoto, Yukiko Nakaya, Shosuke Okamoto, Mayako Tada
Publikováno v:
Biological and Pharmaceutical Bulletin. 21:105-108
We synthesized a new affinity gel (PKSI-Toyopearl) using a selective synthetic inhibitor of plasma kallikrein (PKSI-527) as an affinity ligand, and employed it for the rapid purification of plasma kallikrein from human plasma. Human plasma activated
Autor:
Utako Okamoto, Akiko Hijikata-Okunomiya, Mayako Tada, Shosuke Okamoto, Noboru Horie, Yoshio Okada, Yuko Tsuda, Keiko Wanaka
Publikováno v:
Biologicalpharmaceutical bulletin. 24(5)
We established a simple method for the purification of human plasma kallikrein (PK) by affinity chromatography and characterized it by analytical reverse phase-HPLC and Time of Flight Mass Spectroscopy (TOF-MS). The affinity resin (PKSI-Toyopearl) wa
Autor:
Yuko Tsuda, Utako Okamoto, Akiko Hijikata-Okunomiya, Shosuke Okamoto, Keiko Wanaka, Mayako Tada, Yoshio Okada
Publikováno v:
Chemicalpharmaceutical bulletin. 48(12)
Based on structure-activity relationship studies, we designed and synthesized plasmin (PL) and plasma kallikrein (PK) inhibitors. Trans-(4-aminomethylcyclohexanecarbonyl)-Tyr(O-Pic)-octylamide inhibited PL, PK, urokinase (UK) and thrombin (TH) with I
Autor:
Yuko Tsuda, Mayako Tada, oshikazu Matsumoto, Shosuke Okamoto, Akiko Hijikata-Okunomiya, Keiko Wanaka, Yoshio Okada
Publikováno v:
Chemicalpharmaceutical bulletin. 48(2)
Various compounds were synthesized by combining three components at positions P1, P1' and P2'. Of these, N-(trans-4-aminomethylcyclohexanecarbonyl)-Tyr(O-2-bromobenzylo xycarbonyl)- octylamide inhibited plasmin selectively with IC50 values of 0.80 an