Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Maya-Martinez R"'
Autor:
Xu, Y, Maya-Martinez, R, Guthertz, N, Heath, GR, Manfield, IW, Breeze, A, Sobott, F, Foster, R, Radford, SE
Human islet amyloid polypeptide (hIAPP) self-assembles into amyloid fibrils which deposit in pancreatic islets of type 2 diabetes (T2D) patients. Here, we applied chemical kinetics to study the mechanism of amyloid assembly of wild-type hIAPP and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::2281ca2f28697c59f9d24c7f6a89a753
https://eprints.whiterose.ac.uk/183086/17/s41467-022-28660-7.pdf
https://eprints.whiterose.ac.uk/183086/17/s41467-022-28660-7.pdf
Autor:
Meunier-Carmenate Y; Laboratorio de Bioquímica y Resonancia Magnética Nuclear, Centro de Investigaciones Químicas-IICBA, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico., Valdés-García G; Centro de Investigacion en Dinámica Celular-IICBA, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico., Maya-Martinez R; Laboratorio de Bioquímica y Resonancia Magnética Nuclear, Centro de Investigaciones Químicas-IICBA, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico., French-Pacheco L; Laboratorio de Bioquímica y Resonancia Magnética Nuclear, Centro de Investigaciones Químicas-IICBA, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico., Fernández-Silva A; Laboratorio de Bioquímica y Resonancia Magnética Nuclear, Centro de Investigaciones Químicas-IICBA, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico., González-Onofre Y; Laboratorio de Bioquímica y Resonancia Magnética Nuclear, Centro de Investigaciones Químicas-IICBA, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico., Millan-Pacheco C; Facultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico., Pastor N; Centro de Investigacion en Dinámica Celular-IICBA, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico., Amero C; Laboratorio de Bioquímica y Resonancia Magnética Nuclear, Centro de Investigaciones Químicas-IICBA, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico.
Publikováno v:
Biochemistry [Biochemistry] 2023 Mar 07; Vol. 62 (5), pp. 1000-1011. Date of Electronic Publication: 2023 Feb 21.
Autor:
Xu Y; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, LS2 9JT, United Kingdom., Maya-Martinez R; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, LS2 9JT, United Kingdom., Radford SE; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, LS2 9JT, United Kingdom.
Publikováno v:
Essays in biochemistry [Essays Biochem] 2022 Dec 16; Vol. 66 (7), pp. 959-975.
Autor:
Maya-Martinez R; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Xu Y; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Guthertz N; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Walko M; Astbury Centre for Structural Molecular Biology, School of Chemistry, University of Leeds, Leeds, United Kingdom., Karamanos TK; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Sobott F; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Breeze AL; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Radford SE; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom. Electronic address: s.e.radford@leeds.ac.uk.
Publikováno v:
The Journal of biological chemistry [J Biol Chem] 2022 Dec; Vol. 298 (12), pp. 102659. Date of Electronic Publication: 2022 Oct 31.
Autor:
Ulamec SM; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Maya-Martinez R; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Byrd EJ; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Dewison KM; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Xu Y; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Willis LF; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Sobott F; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Heath GR; Astbury Centre for Structural Molecular Biology, School of Physics & Astronomy, University of Leeds, Leeds, LS2 9JT, UK., van Oosten Hawle P; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Buchman VL; School of Biosciences, Cardiff University, Cardiff, CF10 3AX, UK.; Belgorod State National Research University, 85 Pobedy Street, Belgorod, 308015, Belgorod Region, Russian Federation., Radford SE; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK. S.E.Radford@leeds.ac.uk., Brockwell DJ; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK. D.J.Brockwell@leeds.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2022 Aug 25; Vol. 13 (1), pp. 4986. Date of Electronic Publication: 2022 Aug 25.
Autor:
Xu Y; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Maya-Martinez R; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Guthertz N; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Heath GR; Astbury Centre for Structural Molecular Biology, School of Physics and Astronomy, University of Leeds, Leeds, LS2 9JT, UK., Manfield IW; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Breeze AL; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Sobott F; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Foster R; Astbury Centre for Structural Molecular Biology, School of Chemistry, University of Leeds, Leeds, LS2 9JT, UK. r.foster@leeds.ac.uk., Radford SE; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK. S.E.Radford@leeds.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2022 Feb 24; Vol. 13 (1), pp. 1040. Date of Electronic Publication: 2022 Feb 24.
Autor:
Liberini, Elisa1 (AUTHOR) elisa@liberini.de, Fan, Sook-Ha1,2 (AUTHOR) fanfsh7@gmail.com, Bayer, Arnold S.2,3 (AUTHOR), Beck, Christian4 (AUTHOR) c.beck@uni-tuebingen.de, Biboy, Jacob5 (AUTHOR) jacob.biboy@newcastle.ac.uk, François, Patrice6 (AUTHOR) pf.patrice.francois@gmail.com, Gray, Joe5 (AUTHOR) joe.gray@newcastle.ac.uk, Hipp, Katharina7 (AUTHOR) katharina.hipp@tuebingen.mpg.de, Koch, Iris7 (AUTHOR) iris.koch@tuebingen.mpg.de, Peschel, Andreas4,8 (AUTHOR) andreas.peschel@uni-tuebingen.de, Sailer, Brigitte7 (AUTHOR) brigitte.sailer@tuebingen.mpg.de, Vollmer, Daniela5 (AUTHOR) daniela.vollmer@newcastle.ac.uk, Vollmer, Waldemar5,9 (AUTHOR) waldemar.vollmer@newcastle.ac.uk, Götz, Friedrich1,8 (AUTHOR) friedrich.goetz@uni-tuebingen.de
Publikováno v:
International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 17, p9251. 16p.
Autor:
Flores‐Fernandez, Jose Miguel1,2,3 (AUTHOR), Pesch, Verena4 (AUTHOR), Sriraman, Aishwarya1,2 (AUTHOR), Chimal‐Juarez, Enrique1 (AUTHOR), Amidian, Sara1,2 (AUTHOR), Wang, Xiongyao1 (AUTHOR), Duckering, Caleb1,2 (AUTHOR), Fang, Andrew1,2 (AUTHOR), Reithofer, Sara4 (AUTHOR), Ma, Liang4 (AUTHOR), Cortez, Leonardo M.1,5 (AUTHOR), Sim, Valerie L.1,5,6 (AUTHOR), Tamgüney, Gültekin4,7 (AUTHOR) erdem@fz-juelich.de, Wille, Holger1,2,6 (AUTHOR) wille@ualberta.ca
Publikováno v:
Bioengineering & Translational Medicine. Jul2024, Vol. 9 Issue 4, p1-16. 16p.
Autor:
Smith HI; Astbury Centre for Structural Molecular Biology, School of Molecular & Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Guthertz N; Astbury Centre for Structural Molecular Biology, School of Molecular & Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Cawood EE; Astbury Centre for Structural Molecular Biology, School of Molecular & Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.; School of Chemistry, University of Leeds, Leeds, United Kingdom., Maya-Martinez R; Astbury Centre for Structural Molecular Biology, School of Molecular & Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Breeze AL; Astbury Centre for Structural Molecular Biology, School of Molecular & Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Radford SE; Astbury Centre for Structural Molecular Biology, School of Molecular & Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom s.e.radford@leeds.ac.uk.
Publikováno v:
The Journal of biological chemistry [J Biol Chem] 2020 Aug 28; Vol. 295 (35), pp. 12474-12484. Date of Electronic Publication: 2020 Jul 13.
A short motif in the N-terminal region of α-synuclein is critical for both aggregation and function.
Autor:
Doherty CPA; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom., Ulamec SM; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom., Maya-Martinez R; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom., Good SC; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom., Makepeace J; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom., Khan GN; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom., van Oosten-Hawle P; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom., Radford SE; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom. S.E.Radford@leeds.ac.uk., Brockwell DJ; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom. D.J.Brockwell@leeds.ac.uk.
Publikováno v:
Nature structural & molecular biology [Nat Struct Mol Biol] 2020 Mar; Vol. 27 (3), pp. 249-259. Date of Electronic Publication: 2020 Mar 09.