A novel peptide antagonist of the human growth hormone receptor

Autor: Sebastian J C M M Neggers, Khairun Nahar, Reetobrata Basu, John J. Kopchick, Justin M. Holub, Zachary Hall, Maya R. Sattler, Olivia Kerekes, Prateek Kulkarni

Publikováno v: The Journal of Biological Chemistry
Journal of Biological Chemistry, 296:100588. American Society for Biochemistry and Molecular Biology Inc.

Excess circulating human growth hormone (hGH) in vivo is linked to metabolic and growth disorders such as cancer, diabetes, and acromegaly. Consequently, there is considerable interest in developing antagonists of hGH action. Here, we present the des

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c62e5e21fc675293250403c121486db
https://doi.org/10.1016/j.jbc.2021.100588