Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Maya Mitalipova"'
Autor:
Xin Huang, Kyoung-mi Park, Paul Gontarz, Bo Zhang, Joshua Pan, Zachary McKenzie, Laura A. Fischer, Chen Dong, Sabine Dietmann, Xiaoyun Xing, Pavel V. Shliaha, Jihong Yang, Dan Li, Junjun Ding, Tenzin Lungjangwa, Maya Mitalipova, Shafqat A. Khan, Sumeth Imsoonthornruksa, Nick Jensen, Ting Wang, Cigall Kadoch, Rudolf Jaenisch, Jianlong Wang, Thorold W. Theunissen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Although the interactors of pluripotency factors have been identified in mouse embryonic stem cells (ESCs), their interactors in human ESCs remain unexplored. Here the authors map OCT4 protein interactions in naïve and primed human ESCs to find spec
Externí odkaz:
https://doaj.org/article/475ca4c998cb484bb6963209f6ebdc13
Autor:
Danielle L. Tomasello, Jiyoon L. Kim, Yara Khodour, Jasmine M. McCammon, Maya Mitalipova, Rudolf Jaenisch, Anthony H. Futerman, Hazel Sive
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103551- (2022)
Summary: The complex 16p11.2 deletion syndrome (16pdel) is accompanied by neurological disorders, including epilepsy, autism spectrum disorder, and intellectual disability. We demonstrated that 16pdel iPSC differentiated neurons from affected people
Externí odkaz:
https://doaj.org/article/0c93a35df15045fcb96faf86b6dca524
Autor:
Yakov Chudnovsky, Dohoon Kim, Siyuan Zheng, Warren A. Whyte, Mukesh Bansal, Mark-Anthony Bray, Shuba Gopal, Matthew A. Theisen, Steve Bilodeau, Prathapan Thiru, Julien Muffat, Omer H. Yilmaz, Maya Mitalipova, Kevin Woolard, Jeongwu Lee, Riko Nishimura, Nobuo Sakata, Howard A. Fine, Anne E. Carpenter, Serena J. Silver, Roel G.W. Verhaak, Andrea Califano, Richard A. Young, Keith L. Ligon, Ingo K. Mellinghoff, David E. Root, David M. Sabatini, William C. Hahn, Milan G. Chheda
Publikováno v:
Cell Reports, Vol 6, Iss 2, Pp 313-324 (2014)
Glioblastoma (GBM) harbors subpopulations of therapy-resistant tumor-initiating cells (TICs) that are self-renewing and multipotent. To understand the regulation of the TIC state, we performed an image-based screen for genes regulating GBM TIC mainte
Externí odkaz:
https://doaj.org/article/ec2905833cc54c5e82b2fee25ecd2d48
Autor:
Hazel Sive, Maya Mitalipova, Jasmine M. McCammon, Yara Khodour, Anthony H. Futerman, Jiyoon L. Kim, Rudolf Jaenisch, Danielle L. Tomasello
Publikováno v:
iScience
iScience, Vol 25, Iss 1, Pp 103551-(2022)
iScience, Vol 25, Iss 1, Pp 103551-(2022)
Summary The complex 16p11.2 deletion syndrome (16pdel) is accompanied by neurological disorders, including epilepsy, autism spectrum disorder, and intellectual disability. We demonstrated that 16pdel iPSC differentiated neurons from affected people s
Autor:
Nick O Jensen, Maya Mitalipova, Jihong Yang, Xin Huang, Zachary M. McKenzie, Pavel V. Shliaha, Tenzin Lungjangwa, Cigall Kadoch, Sumeth Imsoonthornruksa, Xiaoyun Xing, Thorold W. Theunissen, Dan Li, Ting Wang, Chen Dong, Rudolf Jaenisch, Kyoung-mi Park, Shafqat Ali Khan, Sabine Dietmann, Junjun Ding, Jianlong Wang, Paul Gontarz, Laura A. Fischer, Joshua Pan, Bo Zhang
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Understanding the molecular underpinnings of pluripotency is a prerequisite for optimal maintenance and application of embryonic stem cells (ESCs). While the protein-protein interactions of core pluripotency factors have been identified in mouse ESCs
Autor:
Jiyoon L. Kim, Yara Khodour, Hazel Sive, Maya Mitalipova, Rudolf Jaenisch, Anthony H. Futerman, Jasmine M. McCammon, Danielle L. Tomasello
The complex 16p11.2 Deletion Syndrome (16pdel) is accompanied by neurological disorders, including epilepsy, autism spectrum disorder and intellectual disability. We demonstrate that 16pdel iPSC differentiated neurons showed augmented local field pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a553b0da885411b315379d38d45da50
https://doi.org/10.1101/2021.03.02.433619
https://doi.org/10.1101/2021.03.02.433619
Autor:
Hazel Sive, Jasmine M. McCammon, Yara Khodour, Maya Mitalipova, Jiyoon L. Kim, Danielle L. Tomasello, Rudolf Jaenisch, Anthony H. Futerman
Publikováno v:
SSRN Electronic Journal.
The complex 16p11.2 Deletion Syndrome (16pdel) is accompanied by neurological disorders, including epilepsy, autism spectrum disorder and intellectual disability. We demonstrated that 16pdel iPSC differentiated neurons show augmented local field pote
Autor:
Devon S. Svoboda, Peter Berube, Maya Mitalipova, Shupei Zhang, Rudolf Jaenisch, M. Inmaculada Barrasa, Rosalie G. J. Rietjens, Dongdong Fu, Jian Shu, Leonard D. Shultz, George W. Bell
Publikováno v:
Proc Natl Acad Sci U S A
Microglia are essential for maintenance of normal brain function, with dysregulation contributing to numerous neurological diseases. Protocols have been developed to derive microglia-like cells from human induced pluripotent stem cells (hiPSCs). Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ae280fb5e5e3cfd51231ccd5f256c9
https://europepmc.org/articles/PMC6911218/
https://europepmc.org/articles/PMC6911218/
Autor:
Kevin D. Woolard, Warren A. Whyte, Richard A. Young, Siyuan Zheng, Dohoon Kim, Keith L. Ligon, Roel G.W. Verhaak, Jeongwu Lee, Anne E. Carpenter, Steve Bilodeau, Maya Mitalipova, Ömer H. Yilmaz, Mark-Anthony Bray, David M. Sabatini, Shuba Gopal, Ingo K. Mellinghoff, Andrea Califano, Riko Nishimura, Mukesh Bansal, Yakov Chudnovsky, William C. Hahn, David E. Root, Julien Muffat, Nobuo Sakata, Matthew A. Theisen, Milan G. Chheda, Prathapan Thiru, Howard A. Fine, Serena J. Silver
Publikováno v:
Cell Reports, Vol 6, Iss 2, Pp 313-324 (2014)
Cell reports, vol 6, iss 2
Elsevier Open Access
Cell reports, vol 6, iss 2
Elsevier Open Access
Glioblastoma (GBM) harbors subpopulations of therapy-resistant tumor-initiating cells (TICs) that are self-renewing and multipotent. To understand the regulation of the TIC state, we performed an image-based screen for genes regulating GBM TIC mainte
Autor:
Haoyi Wang, Benjamin E. Powell, Meelad M. Dawlaty, Ana C. D’Alessio, Richard A. Young, Maya Mitalipova, Nathanael S. Gray, Dina A. Faddah, Thorold W. Theunissen, Dorothea Maetzel, Zi Peng Fan, Jessica Reddy, Kibibi Ganz, Qing Gao, Sumeth Imsoonthornruksa, Linyu Shi, Rudolf Jaenisch, Tenzin Lungjangwa, Yonatan Stelzer, Jianming Zhang, Sudharshan Rangarajan
Publikováno v:
Cell Stem Cell
Summary Embryonic stem cells (ESCs) of mice and humans have distinct molecular and biological characteristics, raising the question of whether an earlier, “naive” state of pluripotency may exist in humans. Here we took a systematic approach to id