Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Maya K, Weigel"'
Autor:
Kimberly Prescott, Alexandra E. Münch, Evan Brahms, Maya K. Weigel, Kenya Inoue, Marion S. Buckwalter, Shane A. Liddelow, Todd C. Peterson
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2024)
Microglia and astrocytes play an important role in the neuroinflammatory response and contribute to both the destruction of neighboring tissue as well as the resolution of inflammation following stroke. These reactive glial cells are highly heterogen
Externí odkaz:
https://doaj.org/article/e5de08f0b9ff44f7ba639e4ce88040cc
Autor:
Kevin A. Guttenplan, Maya K. Weigel, Drew I. Adler, Julien Couthouis, Shane A. Liddelow, Aaron D. Gitler, Ben A. Barres
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Astrocyte activation may contribute to neurodegenerative disease. Here the authors show that the combined knockout of three factors known to promote astrogliosis, IL-1α, TNFα and C1qa, leads to improved survival in the SOD1 G93A mouse model of ALS.
Externí odkaz:
https://doaj.org/article/04bb3c77114848c1a13fa651c535c520
Autor:
Prageeth R. Wijewardhane, Maya K. Weigel, Gaurav Chopra, Uriel Rufen-Blanchette, Priya Prakash, Jacob A. Blum, Shane A. Liddelow, Jonathan Fine, Aaron D. Gitler, Mikaela C. Neal, Kimberley D. Bruce, Philip Hasel, Kevin A. Guttenplan, Alexandra E. Münch, Ben A. Barres
Publikováno v:
Nature. 599:102-107
Astrocytes regulate the response of the central nervous system to disease and injury and have been hypothesized to actively kill neurons in neurodegenerative disease1–6. Here we report an approach to isolate one component of the long-sought astrocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09d67a7fcbc3e7da504806c704c77cce
https://doi.org/10.1038/s41586-021-03960-y
https://doi.org/10.1038/s41586-021-03960-y
Autor:
Daniela Rojo, Anna Badner, Louisa Dal Cengio, Samuel Kim, Noriaki Sakai, Jacob Greene, Ella Eisinger, Caroline Arellano-Garcia, Lindsey C. Mehl, Mohammad E. Gumma, Rebecca L. Soyk, Julia Ransom, Maya K. Weigel, Belgin Yalçın, Samuel E. Jones, Hanna M. Ollila, Seiji Nishino, Erin M. Gibson
Myelination depends on maintenance of oligodendrocytes that arise from oligodendrocyte precursor cells (OPCs). We show that the dynamic nature of oligodendroglia and myelination are regulated by the circadian transcription factor BMAL1. Bmal1 knockdo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82829a9b2ea84c44e58212572c0ba3cb
https://doi.org/10.1101/2022.04.28.489946
https://doi.org/10.1101/2022.04.28.489946
Autor:
Kevin A, Guttenplan, Maya K, Weigel, Priya, Prakash, Prageeth R, Wijewardhane, Philip, Hasel, Uriel, Rufen-Blanchette, Alexandra E, Münch, Jacob A, Blum, Jonathan, Fine, Mikaela C, Neal, Kimberley D, Bruce, Aaron D, Gitler, Gaurav, Chopra, Shane A, Liddelow, Ben A, Barres
Publikováno v:
Nature. 599(7883)
Astrocytes regulate the response of the central nervous system to disease and injury and have been hypothesized to actively kill neurons in neurodegenerative disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e428f0299d70b7be92a61bad4c343c69
https://pubmed.ncbi.nlm.nih.gov/34616039
https://pubmed.ncbi.nlm.nih.gov/34616039
Publikováno v:
Developmental neurobiologyREFERENCES. 81(3)
Though much is known about microtubule organization and microtubule-based transport in neurons, the development and function of microtubules in glia are more enigmatic. In this review, we provide an overview of the literature on microtubules in ramif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b1a1309db31b24a049e8e1c09e53cd
https://pubmed.ncbi.nlm.nih.gov/32324338
https://pubmed.ncbi.nlm.nih.gov/32324338
Autor:
Rana N. El-Danaf, Alexandra E. Münch, Drew I. Adler, Benjamin K. Stafford, Andrew D. Huberman, Shane A. Liddelow, Maya K. Weigel, Kevin A. Guttenplan
Publikováno v:
Cell Rep
Glaucoma is a neurodegenerative disease that features the death of retinal ganglion cells (RGCs) in the retina, often as a result of prolonged increases in intraocular pressure. We show that preventing the formation of neuroinflammatory reactive astr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e467eee293a0da945cd06570c99f3ffc
https://pubmed.ncbi.nlm.nih.gov/32579912
https://pubmed.ncbi.nlm.nih.gov/32579912