Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Maya Guncheva"'
Autor:
Denitsa Yancheva, Maria Argirova, Irina Georgieva, Vanya Milanova, Maya Guncheva, Miroslav Rangelov, Nadezhda Todorova, Rumiana Tzoneva
Publikováno v:
Molecules, Vol 29, Iss 10, p 2400 (2024)
(1) Background: The aim of the work is the evaluation of in vitro antiproliferative and pro-apoptotic activity of four benzimidazole derivatives containing colchicine-like and catechol-like moieties with methyl group substitution in the benzimidazole
Externí odkaz:
https://doaj.org/article/a92ac4c02fa04138847d7d3934b2f048
Autor:
Paula Ossowicz-Rupniewska, Joanna Klebeko, Irina Georgieva, Sonia Apostolova, Łukasz Struk, Svetla Todinova, Rumiana Dimitrova Tzoneva, Maya Guncheva
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 496 (2024)
Betulinic acid (BA) is a natural pentacyclic triterpene with diverse biological activities. However, its low water solubility limits its pharmaceutical application. The conversion of pharmaceutically active molecules into ionic liquids (ILs) is a pro
Externí odkaz:
https://doaj.org/article/083e0390eea74d1e99f779e334b35503
Publikováno v:
Acta Chimica Slovenica, Vol 67, Iss 1, Pp 253-259 (2020)
For the first time Helix lucorum hemocyanin (HlH) has been feruloylated. Two HlH conjugates with 40- and 120- ferulic acid residues were prepared, denoted as FA-HlH-1 and FA-HlH-2. Expectedly, the feruloylation of HlH induced a rearrangement of the p
Externí odkaz:
https://doaj.org/article/3051f549d25340d09dea72b6bc4e7728
Autor:
Maria Argirova, Maya Guncheva, Georgi Momekov, Emiliya Cherneva, Rositsa Mihaylova, Miroslav Rangelov, Nadezhda Todorova, Petko Denev, Kameliya Anichina, Anelia Mavrova, Denitsa Yancheva
Publikováno v:
Molecules, Vol 28, Iss 1, p 291 (2022)
1H-benzimidazol-2-yl hydrazones with varying hydroxy and methoxy phenyl moieties were designed. Their effect on tubulin polymerization was evaluated in vitro on porcine tubulin. The compounds elongated the nucleation phase and slowed down the tubulin
Externí odkaz:
https://doaj.org/article/6b22eca3d461470f83ff4698263060ff
Autor:
Joanna Klebeko, Paula Ossowicz-Rupniewska, Ewelina Świątek, Joanna Szachnowska, Ewa Janus, Stefka G. Taneva, Elena Krachmarova, Maya Guncheva
Publikováno v:
Molecules, Vol 27, Iss 1, p 216 (2021)
In recent years, numerous studies have shown that conversion of conventional drugs in ionic liquid (IL) formulation could be a successful strategy to improve their physicochemical properties or suggest a new route of administration. We report the syn
Externí odkaz:
https://doaj.org/article/6ee50456ae454c67afbb88349140ea2d
Autor:
Maya Guncheva, Krassimira Idakieva, Svetla Todinova, Denitsa Yancheva, Tsvetelina Paunova-Krasteva, Paula Ossowicz, Ewa Janus
Publikováno v:
Molecules, Vol 26, Iss 6, p 1714 (2021)
Novel biocompatible compounds that stabilize proteins in solution are in demand for biomedical and/or biotechnological applications. Here, we evaluated the effect of six ionic liquids, containing mono- or dicholinium [Chol]1or2 cation and anions of c
Externí odkaz:
https://doaj.org/article/552568e741244e30b9054aa6b6479a52
Autor:
Paula Ossowicz, Proletina Kardaleva, Maya Guncheva, Joanna Klebeko, Ewelina Świątek, Ewa Janus, Denitsa Yancheva, Ivan Angelov
Publikováno v:
Molecules, Vol 25, Iss 1, p 90 (2019)
The development of ionic liquids based on active pharmaceutical ingredients (API-ILs) is a possible solution to some of the problems of solid and/or hydrophobic drugs such as low solubility and bioavailability, polymorphism and an alternative route o
Externí odkaz:
https://doaj.org/article/4fb41a7c584c490bb5dbec5fa0ee8e34
Publikováno v:
Proceedings, Vol 22, Iss 1, p 13 (2019)
Some cancer cells hyperexpress folate receptors (FR); therefore, folate-derivatized deliverysystems are applied for a selective delivery of chemotherapeutics. [...]
Externí odkaz:
https://doaj.org/article/364d1a9510f94704bff6b88714ac0c7b
Autor:
Maya Guncheva
Publikováno v:
The Protein Journal. 41:369-380
Ionic liquids (ILs) exhibit potential as excipients to stabilize proteins in solutions. This mini-review is not a detailed reference book on ILs, rather a brief overview of the main achievements published in the literature on their effect on protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60aa4e397ecba8aeb9b7a4af36460c9c
https://doi.org/10.1007/s10930-022-10058-5
https://doi.org/10.1007/s10930-022-10058-5
Autor:
Bistra Atanassova Stamboliyska, Stefan Tapanov, Daniela Kovatcheva, Stela Atanasova-Vladimirova, Bogdan Ranguelov, Denitsa Yancheva, Evelina Velcheva, Simeon Stoyanov, Maya Guncheva, Albena Lederer, Dieter Fischer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01360f8648ac72612555c15cafcbc292
https://doi.org/10.2139/ssrn.4412870
https://doi.org/10.2139/ssrn.4412870
