Zobrazeno 1 - 10
of 248
pro vyhledávání: '"Maya, Simionescu"'
Autor:
Loredana Iacobescu, Andrea Olivia Ciobanu, Razvan Macarie, Mihaela Vadana, Letitia Ciortan, Monica Madalina Tucureanu, Elena Butoi, Maya Simionescu, Dragos Vinereanu
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8499-8511 (2024)
Recent studies reported that circulating microRNAs (miRNAs) can target different metalloproteases (MMPs) involved in matrix remodeling and plaque vulnerability. Consequently, they might have a role in the diagnosis and prognosis of coronary artery di
Externí odkaz:
https://doaj.org/article/603256f361ea443085e231b4c09a986a
Autor:
Geanina Voicu, Cristina Ana Mocanu, Florentina Safciuc, Maria Anghelache, Mariana Deleanu, Sergiu Cecoltan, Mariana Pinteala, Cristina Mariana Uritu, Ionel Droc, Maya Simionescu, Ileana Manduteanu, Manuela Calin
Publikováno v:
Materials Today Bio, Vol 20, Iss , Pp 100620- (2023)
Runx2 is a key transcription factor involved in valvular interstitial cells (VIC) osteodifferentiation, a process actively entwined with the calcific aortic valve disease (CAVD). We hypothesize that a strategy intended to silence Runx2 could be a val
Externí odkaz:
https://doaj.org/article/53f5761dc0514927ade14d308f53a6ed
Autor:
Andreea Cristina Mihaila, Letitia Ciortan, Monica Madalina Tucureanu, Maya Simionescu, Elena Butoi
Publikováno v:
Cells, Vol 13, Iss 3, p 208 (2024)
Following myocardial infarction (MI), blood neutrophils quickly and extensively infiltrate the heart, where they are temporally polarized into pro-inflammatory (N1) and anti-inflammatory (N2) subpopulations. Neutrophil transmigration is rapidly follo
Externí odkaz:
https://doaj.org/article/6add2033f83a4107922db45fa95d30eb
Autor:
Elena Valeria Fuior, Evangelia Zvintzou, Theodosios Filippatos, Katerina Giannatou, Victoria Mparnia, Maya Simionescu, Anca Violeta Gafencu, Kyriakos E. Kypreos
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2696 (2023)
Peroxisome proliferator-activated receptors (PPARs) are a group of ligand-binding transcription factors with pivotal action in regulating pleiotropic signaling pathways of energetic metabolism, immune responses and cell proliferation and differentiat
Externí odkaz:
https://doaj.org/article/443f5409a0ed4f7e890e82bc535d5e00
Autor:
Mihai Bogdan Preda, Carmen Alexandra Neculachi, Ioana Madalina Fenyo, Ana-Maria Vacaru, Mihai Alin Publik, Maya Simionescu, Alexandrina Burlacu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-12 (2021)
Abstract Mesenchymal stromal cells (MSC) are attractive tools for cell-based therapy, yet the mechanisms underlying their migration and survival post-transplantation are unclear. Accumulating evidence indicates that MSC apoptosis modulates both innat
Externí odkaz:
https://doaj.org/article/c870d193b4064f9b8e3320f0af18e8c8
Autor:
Simona-Adriana Manea, Mihaela-Loredana Vlad, Alexandra-Gela Lazar, Horia Muresian, Maya Simionescu, Adrian Manea
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2382 (2022)
Dysregulated epigenetic mechanisms promote transcriptomic and phenotypic alterations in cardiovascular diseases. The role of histone methylation-related pathways in atherosclerosis is largely unknown. We hypothesize that lysine-specific demethylase 1
Externí odkaz:
https://doaj.org/article/1e1de9347e21402abd50c0a8ada04168
Autor:
Andreea C. Mihaila, Letitia Ciortan, Razvan D. Macarie, Mihaela Vadana, Sergiu Cecoltan, Mihai Bogdan Preda, Ariana Hudita, Ana-Maria Gan, Gabriel Jakobsson, Monica M. Tucureanu, Elena Barbu, Serban Balanescu, Maya Simionescu, Alexandru Schiopu, Elena Butoi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophils have been classically viewed as a homogenous population. Recently, neutrophils were phenotypically classified into pro-inflammatory N1 and anti-inflammatory N2 sub-populations, but the functional differences between the two subtypes are n
Externí odkaz:
https://doaj.org/article/c7e22488342b47439dfb2d1d1d46675e
Autor:
Simona-Adriana Manea, Mihaela-Loredana Vlad, Ioana Madalina Fenyo, Alexandra-Gela Lazar, Monica Raicu, Horia Muresian, Maya Simionescu, Adrian Manea
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
NADPH oxidase (Nox)-derived reactive oxygen species (ROS) are instrumental in all inflammatory phases of atherosclerosis. Dysregulated histone deacetylase (HDAC)-related epigenetic pathways have been mechanistically linked to alterations in gene expr
Externí odkaz:
https://doaj.org/article/f9222191c4894c2ea160952311591c0f
Autor:
Simona-Adriana Manea, Mihaela-Loredana Antonescu, Ioana Madalina Fenyo, Monica Raicu, Maya Simionescu, Adrian Manea
Publikováno v:
Redox Biology, Vol 16, Iss , Pp 332-343 (2018)
Reactive oxygen species (ROS) generated by up-regulated NADPH oxidase (Nox) contribute to structural-functional alterations of the vascular wall in diabetes. Epigenetic mechanisms, such as histone acetylation, emerged as important regulators of gene
Externí odkaz:
https://doaj.org/article/32808910f45d4220b45852d535d665fb
Autor:
Alexandra-Gela Lazar, Mihaela-Loredana Vlad, Adrian Manea, Maya Simionescu, Simona-Adriana Manea
Publikováno v:
Antioxidants, Vol 10, Iss 9, p 1356 (2021)
Accumulating evidence implicates the histone acetylation-based epigenetic mechanisms in the pathoetiology of diabetes-associated micro-/macrovascular complications. Diabetic kidney disease (DKD) is a progressive chronic inflammatory microvascular dis
Externí odkaz:
https://doaj.org/article/32c9854163a94f8cb604c1e5802f6a24