Zobrazeno 1 - 9
of 9
pro vyhledávání: '"May-Linda Lepage"'
Autor:
Yann Neuzillet, Xavier Paoletti, Slah Ouerhani, Pierre Mongiat-Artus, Hany Soliman, Hugues de The, Mathilde Sibony, Yves Denoux, Vincent Molinie, Aurélie Herault, May-Linda Lepage, Pascale Maille, Audrey Renou, Dimitri Vordos, Claude-Clément Abbou, Ashraf Bakkar, Bernard Asselain, Nadia Kourda, Amel El Gaaied, Karen Leroy, Agnès Laplanche, Simone Benhamou, Thierry Lebret, Yves Allory, François Radvanyi
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e48993 (2012)
TP53 and FGFR3 mutations are the most common mutations in bladder cancers. FGFR3 mutations are most frequent in low-grade low-stage tumours, whereas TP53 mutations are most frequent in high-grade high-stage tumours. Several studies have reported FGFR
Externí odkaz:
https://doaj.org/article/53f5b53e570340e18b559b078466bd8a
Autor:
Ming-Jun Shi, Jacqueline Fontugne, Aura Moreno-Vega, Xiang-Yu Meng, Clarice Groeneveld, Florent Dufour, Aurélie Kamoun, Sia Viborg Lindskrog, Luc Cabel, Clémentine Krucker, Audrey Rapinat, Claire Dunois-Larde, May-Linda Lepage, Elodie Chapeaublanc, Olivier Levrel, Victoria Dixon, Thierry Lebret, Anna Almeida, Aurélien De Reynies, Natacha Rochel, Lars Dyrskjøt, Yves Allory, François Radvanyi, Isabelle Bernard-Pierrot
Publikováno v:
European Urology
European Urology, In press, ⟨10.1016/j.eururo.2022.09.030⟩
Shi, M J, Fontugne, J, Moreno-Vega, A, Meng, X Y, Groeneveld, C, Dufour, F, Kamoun, A, Viborg Lindskrog, S, Cabel, L, Krucker, C, Rapinat, A, Dunois-Larde, C, Lepage, M L, Chapeaublanc, E, Levrel, O, Dixon, V, Lebret, T, Almeida, A, De Reynies, A, Rochel, N, Dyrskjøt, L, Allory, Y, Radvanyi, F & Bernard-Pierrot, I 2023, ' FGFR3 Mutational Activation Can Induce Luminal-like Papillary Bladder Tumor Formation and Favors a Male Sex Bias ', European Urology, vol. 83, no. 1, pp. 70-81 . https://doi.org/10.1016/j.eururo.2022.09.030
European Urology, In press, ⟨10.1016/j.eururo.2022.09.030⟩
Shi, M J, Fontugne, J, Moreno-Vega, A, Meng, X Y, Groeneveld, C, Dufour, F, Kamoun, A, Viborg Lindskrog, S, Cabel, L, Krucker, C, Rapinat, A, Dunois-Larde, C, Lepage, M L, Chapeaublanc, E, Levrel, O, Dixon, V, Lebret, T, Almeida, A, De Reynies, A, Rochel, N, Dyrskjøt, L, Allory, Y, Radvanyi, F & Bernard-Pierrot, I 2023, ' FGFR3 Mutational Activation Can Induce Luminal-like Papillary Bladder Tumor Formation and Favors a Male Sex Bias ', European Urology, vol. 83, no. 1, pp. 70-81 . https://doi.org/10.1016/j.eururo.2022.09.030
Background: Bladder cancer (BCa) is more common in men and presents differences in molecular subtypes based on sex. Fibroblast growth factor receptor 3 (FGFR3) mutations are enriched in the luminal papillary muscle-invasive BCa (MIBC) and non-MIBC su
Autor:
Yann Neuzillet, Agnès Laplanche, Dimitri Vordos, François Radvanyi, Yves Denoux, Simone Benhamou, Mathilde Sibony, Karina Ofualuka, Alexandre de la Taille, Frédéric Guyon, Yves Allory, Thierry Lebret, Aurélie Hérault, Sandra Rebouissou, Eric Letouzé, Audrey Riou, May-Linda Lepage, Pascale Maillé, Karen Leroy
Publikováno v:
The Journal of Pathology. 227:315-324
The gene cyclin-dependent kinase inhibitor 2A (CDKN2A) is frequently inactivated by deletion in bladder carcinoma. However, its role in bladder tumourigenesis remains unclear. We investigated the role of CDKN2A deletion in urothelial carcinogenesis,
Autor:
Claude-Clément Abbou, Clotilde Théry, Nicolas Stransky, Marie-Hélène Donnadieu, Simone Benhamou, Maille P, Xavier Sastre-Garau, Sophie Krumeich, Isabelle Bernard-Pierrot, François Radvanyi, Battail C, May-Linda Lepage, Yves Allory, Sebastian Amigorena, Thierry Lebret, Marick Laé, Gaël Sugano
Publikováno v:
Oncogene. 30:642-653
Milk fat globule-epidermal growth factor-factor VIII (MFGE8), also called lactadherin or SED1, is a secreted integrin-binding protein that promotes elimination of apoptotic cells by phagocytes leading to tolerogenic immune responses, and vascular end
Autor:
Elodie Chapeaublanc, François Radvanyi, Dimitri Vordos, Yves Denoux, Simone Benhamou, Pascale Soyeux, Isabelle Bernard-Pierrot, Nabila Elarouci, Aurélie Hérault, Yann Neuzillet, Mathilde Sibony, Fabien Reyal, Pascale Maillé, Vincent Molinié, Eric Letouzé, Aurélie Caillault, Xavier Paoletti, Karina Ofualuka, Jennifer Southgate, Thierry Lebret, Aurélien de Reyniès, Sandra Rebouissou, Anne Biton, Clémentine Krucker, Aurélie Kamoun, Yves Allory, May-Linda Lepage, Agnès Laplanche
Publikováno v:
Science Translational Medicine
Science Translational Medicine, 2014, 6 (244), ⟨10.1126/scitranslmed.3008970⟩
Science Translational Medicine, 2014, 6 (244), ⟨10.1126/scitranslmed.3008970⟩
Muscle-invasive bladder carcinoma (MIBC) constitutes a heterogeneous group of tumors with a poor outcome. Molecular stratification of MIBC may identify clinically relevant tumor subgroups and help to provide effective targeted therapies. From seven s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962786e4f4f2987df277d34eb736a2a7
https://hal.science/hal-04093027
https://hal.science/hal-04093027
Autor:
Sandra, Rebouissou, Aurélie, Hérault, Eric, Letouzé, Yann, Neuzillet, Agnès, Laplanche, Karina, Ofualuka, Pascale, Maillé, Karen, Leroy, Audrey, Riou, May-Linda, Lepage, Dimitri, Vordos, Alexandre, de la Taille, Yves, Denoux, Mathilde, Sibony, Frédéric, Guyon, Thierry, Lebret, Simone, Benhamou, Yves, Allory, François, Radvanyi
Publikováno v:
The Journal of pathology. 227(3)
The gene cyclin-dependent kinase inhibitor 2A (CDKN2A) is frequently inactivated by deletion in bladder carcinoma. However, its role in bladder tumourigenesis remains unclear. We investigated the role of CDKN2A deletion in urothelial carcinogenesis,
Autor:
Mathilde Sibony, Anne Biton, Clémentine Krucker, Aurélie Kamoun, Agnès Laplanche, Y. Decoux, Simone Benhamou, Xavier Paoletti, Nabila Elarouci, François Radvanyi, Thierry Lebret, Yves Allory, Jennifer Southgate, Elodie Chapeaublanc, A. De Reynies, Karina Ofualuka, Fabien Reyal, Yann Neuzillet, Eric Letouzé, Vincent Molinié, May-Linda Lepage, Pascale Soyeux, Sandra Rebouissou, Pascale Maillé, Dimitrios Vordos, Aurélie Hérault, Aurélie Caillault
Publikováno v:
Progrès en Urologie
Progrès en Urologie, 2014, 24 (13), pp.806. ⟨10.1016/j.purol.2014.08.053⟩
Progrès en Urologie, 2014, 24 (13), pp.806. ⟨10.1016/j.purol.2014.08.053⟩
Objectifs Les tumeurs de vessie infiltrant le muscle (TVIM) presentent une grande heterogeneite moleculaire et clinique et, parallelement, les etudes de phase II–III ont rapporte un manque d’efficacite des therapies ciblees. L’objectif de cette
Autor:
Jaques Camonis, André Nicolas, Didier Decaudin, Sergio Roman-Roman, Amaury Dumont, Fariba Nemati, David Gentien, Jordan Madic, Pascale Mariani, Xavier Sastre, Nabil Amirouchene-Angelozzi, Guillaume Carita, Nathalie Cassoux, Sophie Piperno-Neumann, Laurence Desjardins, May-Linda Lepage
Publikováno v:
Cancer Research. 74:3915-3915
PURPOSE: Uveal melanoma is the most common primary tumor of the eye in adults. There is no standard adjuvant treatment to prevent metastases and no effective therapy in the metastatic setting. Relevant models of uveal melanoma are necessary to precli
Autor:
Agnès Laplanche, Claude C. Abbou, Claire Dunois‐Larde, Aurélie Hérault, Slah Ouerhani, May-Linda Lepage, Nicolas Stransky, Yves Allory, Simone Benhamou, Isabelle Bernard-Pierrot, François Radvanyi, Thierry Lebret
Publikováno v:
Molecular Cancer Therapeutics. 8:B92-B92
Bladder cancer is estimated to be the fifth most prevalent type of cancer in industrialized countries. In most of the cases (more than 90 %), tumors are urothelial cell carcinoma (UCC). Activating mutations of the fibroblast growth factor receptor 3