Zobrazeno 1 - 10
of 44
pro vyhledávání: '"May Zaw-Thin"'
Autor:
Matin Mohseni, John J. Connell, Christopher Payne, P. Stephen Patrick, Rebecca Baker, Yichao Yu, Bernard Siow, May Zaw-Thin, Tammy L. Kalber, Quentin A. Pankhurst, Mark F. Lythgoe
Publikováno v:
Materials & Design, Vol 191, Iss , Pp - (2020)
Targeted drug delivery systems aim to increase therapeutic effect within the target tissue or organ, while reducing off-target toxicity associated with systemic delivery. Magnetic drug targeting has been shown to be an effective strategy by manipulat
Externí odkaz:
https://doaj.org/article/100a4b2eb45e44b29d55d6d9218f5d53
Autor:
Jessica K. Nelson, May Zaw Thin, Theodore Evan, Steven Howell, Mary Wu, Bruna Almeida, Nathalie Legrave, Duco S. Koenis, Gabriela Koifman, Yoichiro Sugimoto, Miriam Llorian Sopena, James MacRae, Emma Nye, Michael Howell, Ambrosius P. Snijders, Andreas Prachalias, Yoh Zen, Debashis Sarker, Axel Behrens
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The biological roles of deubiquitinating enzymes (DUBs) in pancreatic ductal adenocarcinoma (PDAC) are not fully explored. Here the authors perform activity based proteomics with a loss of function genetic screen and identify that USP25 promotes PDAC
Externí odkaz:
https://doaj.org/article/cd8dab384b2a46bf9a9f3d5ce3b2663f
Autor:
Nur Hayati Jasmin, May Zaw Thin, Robert D. Johnson, Laurence H. Jackson, Thomas A. Roberts, Anna L. David, Mark F. Lythgoe, Philip C. Yang, Sean M. Davidson, Patrizia Camelliti, Daniel J. Stuckey
Publikováno v:
Advanced Science, Vol 8, Iss 11, Pp n/a-n/a (2021)
Abstract Early measurements of tissue viability after myocardial infarction (MI) are essential for accurate diagnosis and treatment planning but are challenging to obtain. Here, manganese, a calcium analogue and clinically approved magnetic resonance
Externí odkaz:
https://doaj.org/article/10ea21f801ac426a8f9e557b3155ffcf
Publikováno v:
Nature Protocols.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0b33eb0ee540e6e4677524fe0da0a47
https://doi.org/10.1038/s41596-023-00838-3
https://doi.org/10.1038/s41596-023-00838-3
Publikováno v:
Nature Reviews Cancer. 21:718-730
The visualization of whole organs and organisms through tissue clearing and fluorescence volumetric imaging has revolutionized the way we look at biological samples. Its application to solid tumours is changing our perception of tumour architecture,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d15623935d74a0e55fbc7a4e678b5950
https://doi.org/10.1038/s41568-021-00382-w
https://doi.org/10.1038/s41568-021-00382-w
Autor:
Jacqueline J.T. Marshall, Joshua J. Cull, Hajed O. Alharbi, May Zaw Thin, Susanna T.E. Cooper, Christopher Barrington, Hannah Vanyai, Thomas Snoeks, Bernard Siow, Alejandro Suáarez-Bonnet, Eleanor Herbert, Daniel J. Stuckey, Angus J.M. Cameron, Fabrice Prin, Andrew C. Cook, Simon L. Priestnall, Sonia Chotani, Owen J. L. Rackham, Daniel N. Meijles, Tim Mohun, Angela Clerk, Peter J. Parker
BackgroundThe protein kinase PKN2 is required for embryonic development, and PKN2 knockout mice die as a result of failure in expansion of mesoderm tissues, cardiac development and neural tube closure. In the adult, cardiomyocyte PKN2 and PKN1 (in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da3f19d1a8b0542a8afece9e9c2fa48
https://openaccess.sgul.ac.uk/id/eprint/114588/1/bcj-2022-0281.pdf
https://openaccess.sgul.ac.uk/id/eprint/114588/1/bcj-2022-0281.pdf
Autor:
Molly M. Stevens, Ulrike Kauscher, Isaac J. Pence, Anika Nagelkerke, Tammy L. Kalber, May Zaw Thin, Daniel J. Stuckey, Mads Sylvest Bergholt, Conor C. Horgan
Publikováno v:
Theranostics
Theranostics, the combination of diagnosis and therapy, has long held promise as a means to achieving personalised precision cancer treatments. However, despite its potential, theranostics has yet to realise significant clinical translation, largely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf6da6afc96caba2b96e2341f7665ed
http://europepmc.org/articles/PMC7778600
http://europepmc.org/articles/PMC7778600
Autor:
Elizabeth K. Sage, May Zaw Thin, Tammy L. Kalber, Mark W. Lowdell, Krishna K. Kolluri, Mark F. Lythgoe, Adam Edwards, Benjamin D. Weil, John Dickson, Tom Sanderson, Sam M. Janes, P. Stephen Patrick
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background MSCTRAIL is a cell-based therapy consisting of human allogeneic umbilical cord-derived MSCs genetically modified to express the anti-cancer protein TRAIL. Though cell-based therapies are typically designed with a target tissue in mind, del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674ce5bb979f7cf115e397f1f642c3df
http://link.springer.com/article/10.1186/s13287-020-01770-z
http://link.springer.com/article/10.1186/s13287-020-01770-z
Stem cell delivery to kidney via minimally invasive ultrasound-guided renal artery injection in mice
Autor:
May Zaw Thin, Daniel J. Stuckey, P. Stephen Patrick, Tammy L. Kalber, Anna L. David, Mark F. Lythgoe, Olumide Ogunlade, Joan Comenge, Paul C. Beard
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Cell-based therapies are promising treatments for various kidney diseases. However, the major hurdle in initiating therapeutic responses is the inefficiency of injection routes to deliver cells to the kidney parenchyma. Systemic injection, such as in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168786d256d4c9b99f6c5da052e4eb33
http://link.springer.com/article/10.1038/s41598-020-64417-2
http://link.springer.com/article/10.1038/s41598-020-64417-2
Autor:
Laura Beaton, Henry F.J. Tregidgo, Sami A. Znati, Sharon Forsyth, Nicholas Counsell, Matthew J. Clarkson, Steven Bandula, Manil Chouhan, Helen L. Lowe, May Zaw Thin, Julian Hague, Dinesh Sharma, Joerg-Matthias Pollok, Brian R. Davidson, Jowad Raja, Graham Munneke, Daniel J. Stuckey, Zainab A. Bascal, Paul E. Wilde, Sarah Cooper, Samantha Ryan, Peter Czuczman, Eveline Boucher, John A. Hartley, David Atkinson, Andrew L. Lewis, Marnix Jansen, Tim Meyer, Ricky A. Sharma
Publikováno v:
Journal of vascular and interventional radiology : JVIR. 33(9)
To assess the safety and tolerability of a vandetanib-eluting radiopaque embolic (BTG-002814) for transarterial chemoembolization (TACE) in patients with resectable liver malignancies.The VEROnA clinical trial was a first-in-human, phase 0, single-ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b33332a99f4fa341c5777365d9389f0
https://pubmed.ncbi.nlm.nih.gov/35526675
https://pubmed.ncbi.nlm.nih.gov/35526675