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of 4
pro vyhledávání: '"May San Martinho"'
Autor:
Paramita Ray, Derek J. Nancarrow, Daysha Ferrer-Torres, Zhuwen Wang, May San Martinho, Tonaye Hinton, Joshua H. Wu, Angeline Wu, Danielle Kim Turgeon, Max A. Hammer, Michael K. Dame, Theodore S. Lawrence, Patrick J. O’Brien, Jason R. Spence, David G. Beer, Dipankar Ray
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 129-149 (2022)
Background & Aims: TP53 mutations underlie Barrett’s esophagus (BE) progression to dysplasia and cancer. During BE progression, the ubiquitin ligase (E3) RNF128/GRAIL switches expression from isoform 2 (Iso2) to Iso1, stabilizing mutant p53. Howeve
Externí odkaz:
https://doaj.org/article/4a56ad18c7804a3bbc16ac9b32c78f2e
Autor:
Zhuwen Wang, Derek J. Nancarrow, Jason R. Spence, D.K. Turgeon, Michael K. Dame, Daysha Ferrer-Torres, Max A. Hammer, Paramita Ray, David G. Beer, Patrick J. O’Brien, Theodore S. Lawrence, Tonaye Hinton, Joshua H. Wu, Angeline Wu, May San Martinho, Dipankar Ray
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 129-149 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims TP53 mutations underlie Barrett’s esophagus (BE) progression to dysplasia and cancer. During BE progression, the ubiquitin ligase (E3) RNF128/GRAIL switches expression from isoform 2 (Iso2) to Iso1, stabilizing mutant p53. However
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
The incidence of esophageal adenocarcinoma (EAC) and other gastrointestinal (GI) cancers have risen dramatically, thus defining the oncogenic drivers to develop effective therapies are necessary. Patients with Barrett's Esophagus (BE), have an elevat
Autor:
May San Martinho, David G. Beer, Zhuwen Wang, Paramita Ray, Jules Lin, Dafydd G. Thomas, Derek J. Nancarrow, Dipankar Ray, Daysha Ferrer-Torres, Kiran H. Lagisetty, Scott R. Owens, Theodore S. Lawrence, Hui Jiang, Tonaye Hinton, Hee-won Yoon, Andrew C. Chang
Publikováno v:
Gastroenterology
Background & Aims Barrett's esophagus (BE) can progress to dysplasia and esophageal adenocarcinoma (EAC), accompanied by mutations in TP53 that increase the stability of its product, p53. We analyzed BE tissues for messenger RNAs (mRNAs) that associa