Zobrazeno 1 - 10
of 14
pro vyhledávání: '"May Sabry"'
Autor:
Robert Torrance, Kim Orchard, Dimitra Peppa, Helena Arellano-Ballestero, Agnieszka Zubiak, Chris Dally, Aljawharah Alrubayyi, Xenia Charalambous, Melina Michael, Trinity Eales, Kushal Das, Maxine G. B. Tran, May Sabry, Mark W. Lowdell
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background Human and mouse natural killer (NK) cells have been shown to develop memory-like function after short-term exposure to the cocktail of IL-12/15/18 or to overnight co-culture with some tumor cell lines. The resulting cells retain enhanced l
Externí odkaz:
https://doaj.org/article/c2c7715cfa204d06820282339a193374
Autor:
May Sabry, Mark W. Lowdell
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 9, Pp 974-984 (2020)
Abstract Adoptive cell therapy (ACT) is an approach to cancer treatment that involves the use of antitumor immune cells to target residual disease in patients after completion of chemo/radiotherapy. ACT has several advantages compared with other appr
Externí odkaz:
https://doaj.org/article/278a7a9614a749e5aa341be426c5b967
Publikováno v:
Cells, Vol 12, Iss 4, p 633 (2023)
Myelodysplastic syndrome (MDS) treatment remains a big challenge due to the heterogeneous nature of the disease and its ability to progress to acute myeloid leukemia (AML). The only curative option is allogeneic hematopoietic stem cell transplantatio
Externí odkaz:
https://doaj.org/article/d21fe91d1ec14a84a98eedb19cbcbf36
Autor:
Grace Hui Ting Yeo, Oscar Juez, Qing Chen, Budhaditya Banerjee, Lendy Chu, Max W Shen, May Sabry, Ive Logister, Richard I Sherwood, David K Gifford
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 3, p e1008789 (2021)
We introduce poly-adenine CRISPR gRNA-based single-cell RNA-sequencing (pAC-Seq), a method that enables the direct observation of guide RNAs (gRNAs) in scRNA-seq. We use pAC-Seq to assess the phenotypic consequences of CRISPR/Cas9 based alterations o
Externí odkaz:
https://doaj.org/article/caf6d122ce4e4d598a6d62fc160301d9
Autor:
May Sabry, Agnieszka Zubiak, Simon P Hood, Poppy Simmonds, Helena Arellano-Ballestero, Eily Cournoyer, Meghavi Mashar, A Graham Pockley, Mark W Lowdell
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218674 (2019)
An emerging cellular immunotherapy for cancer is based on the cytolytic activity of natural killer (NK) cells against a wide range of tumors. Although in vitro activation, or "priming," of NK cells by exposure to pro-inflammatory cytokines, such as i
Externí odkaz:
https://doaj.org/article/9a94e098d2fb4a44a28230a6efbf53a6
Autor:
Kim H. Orchard, Helena Ballestero, Aga Zubiak, Chris Dalley, Deborah Susan Richardson, Rob Torrance, Trinity Eales, Dimitra Peppa, May Sabry, Mark W. Lowdell
Publikováno v:
Blood. 140:4590-4591
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed08851ea6aec2af5f97b851809c1b8c
https://doi.org/10.1182/blood-2022-166175
https://doi.org/10.1182/blood-2022-166175
Autor:
May Sabry, Ive Logister, Grace Hui Ting Yeo, Budhaditya Banerjee, Max W. Shen, Oscar Juez, Qing Chen, Lendy Chu, Richard I. Sherwood, David K. Gifford
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 3, p e1008789 (2021)
PLoS Computational Biology
PLoS Computational Biology
We introduce poly-adenine CRISPR gRNA-based single-cell RNA-sequencing (pAC-Seq), a method that enables the direct observation of guide RNAs (gRNAs) in scRNA-seq. We use pAC-Seq to assess the phenotypic consequences of CRISPR/Cas9 based alterations o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64c98aeca57e6164ca0a0f375b25532
https://doaj.org/article/caf6d122ce4e4d598a6d62fc160301d9
https://doaj.org/article/caf6d122ce4e4d598a6d62fc160301d9
Autor:
Mark W. Lowdell, May Sabry
Publikováno v:
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 9, Iss 9, Pp 974-984 (2020)
Stem Cells Translational Medicine, Vol 9, Iss 9, Pp 974-984 (2020)
Adoptive cell therapy (ACT) is an approach to cancer treatment that involves the use of antitumor immune cells to target residual disease in patients after completion of chemo/radiotherapy. ACT has several advantages compared with other approaches in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c21335f3b3e73bada2bd50f84b4553
https://pubmed.ncbi.nlm.nih.gov/32416056
https://pubmed.ncbi.nlm.nih.gov/32416056
Autor:
May Sabry, Mark W. Lowdell
Publikováno v:
Natural Killer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c69a3978c35431b5e545772f11ccffb
http://www.intechopen.com/articles/show/title/nk-cells-and-cancer
http://www.intechopen.com/articles/show/title/nk-cells-and-cancer
Autor:
Janani Sivakumaran, Stephen Mackinnon, May Sabry, Robert H. Anderson, Konstantinos Giannopoulos, Janet North, Maria Tsirogianni, Ismail Bakhsh, Mark W. Lowdell
Publikováno v:
The Journal of Immunology. 187:6227-6234
Resting human NK cells require a two-stage activation process that we have previously described as “priming” and “triggering.” NK-sensitive tumor cells provide both priming and triggering signals. NK-resistant tumors evade lysis, mostly by fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110c112e8a6f9ba17e0bb45a486a76db
https://doi.org/10.4049/jimmunol.1101640
https://doi.org/10.4049/jimmunol.1101640