The Ameliorative Effect of Pioglitazone against Neuroinflammation Caused by Doxorubicin in Rats

Autor: May M. Alsaud, Ahmad H. Alhowail, Maha A. Aldubayan, Ibtesam S. Almami

Publikováno v: Molecules, Vol 28, Iss 12, p 4775 (2023)

Doxorubicin (DOX) is a chemotherapeutic agent that is linked with complications such as cardiotoxicity and cognitive dysfunction, known as chemobrain. Chemobrain affects up to 75% of cancer survivors, and there are no known therapeutic options for it

Externí odkaz: https://doaj.org/article/da8a762f8f774003bfb8d9a67e311ff7

Protective Effects of Pioglitazone on Cognitive Impairment and the Underlying Mechanisms: A Review of Literature.

Autor: Alhowail A; Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah, Al Qassim, 52452, Kingdom of Saudi Arabia., Alsikhan R; Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah, Al Qassim, 52452, Kingdom of Saudi Arabia.; Department of Pharmacology and Toxicology, Unaizah College of Pharmacy, Qassim University, Unaizah, Al Qassim, 51911, Kingdom of Saudi Arabia., Alsaud M; Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah, Al Qassim, 52452, Kingdom of Saudi Arabia., Aldubayan M; Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah, Al Qassim, 52452, Kingdom of Saudi Arabia., Rabbani SI; Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah, Al Qassim, 52452, Kingdom of Saudi Arabia.

Publikováno v: Drug design, development and therapy [Drug Des Devel Ther] 2022 Aug 31; Vol. 16, pp. 2919-2931. Date of Electronic Publication: 2022 Aug 31 (Print Publication: 2022).