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pro vyhledávání: '"May Kwang-Mei Wang"'
Autor:
May Kwang-Mei Wang, Tao Ren, Hu Liu, Sun-Young Lim, Kyungae Lee, Anna Honko, Huanying Zhou, Julie Dyall, Lisa Hensley, Ashley K Gartin, James M Cunningham
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007322 (2018)
Lassa fever virus (LASV) is endemic in West Africa and causes severe hemorrhagic fever and sensorineural hearing loss. We identified a small molecule inhibitor of LASV and used it to analyze the mechanism of entry. Using a photo-reactive analog that
Externí odkaz:
https://doaj.org/article/818a1fdb391a4e078bd24d33d234937b
Autor:
Ye Tian, May Kwang-Mei Wang, Kyungae Lee, James M. Cunningham, Hu Liu, Xinyong Liu, Sean P. J. Whelan, Emily Mevers, Benjamin Dedic, Veronica Soloveva, Pranav Krishnan
Publikováno v:
Journal of medicinal chemistry. 61(14)
Previous studies identified an adamantane dipeptide piperazine 3.47 that inhibits Ebola virus (EBOV) infection by targeting the essential receptor Niemann–Pick C1 (NPC1). The physicochemical properties of 3.47 limit its potential for testing in viv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cbfe54eee01b16adc00977e7d3d83f
https://pubmed.ncbi.nlm.nih.gov/29920098
https://pubmed.ncbi.nlm.nih.gov/29920098