Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell-driven tumor immunity.

Autor: Ferrari de Andrade L; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA., Tay RE; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA., Pan D; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA., Luoma AM; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA., Ito Y; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA., Badrinath S; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA., Tsoucas D; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Franz B; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA., May KF Jr; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Harvey CJ; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Kobold S; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Pyrdol JW; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Yoon C; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.; Department of Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA., Yuan GC; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Hodi FS; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Dranoff G; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA., Wucherpfennig KW; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA. kai_wucherpfennig@dfci.harvard.edu.; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.

Publikováno v: Science (New York, N.Y.) [Science] 2018 Mar 30; Vol. 359 (6383), pp. 1537-1542.

Ex vivo characterization and isolation of rare memory B cells with antigen tetramers.

Autor: Franz B; Department of Cancer Immunology & AIDS, Dana-Farber Cancer Institute, Boston, MA 02215-5450, USA., May KF Jr, Dranoff G, Wucherpfennig K

Publikováno v: Blood [Blood] 2011 Jul 14; Vol. 118 (2), pp. 348-57. Date of Electronic Publication: 2011 May 06.

Immune competence of cancer-reactive T cells generated de novo in adult tumor-bearing mice.

Autor: May KF Jr; Division of Cancer Immunology, Department of Pathology, Ohio State University Medical Center and Comprehensive Cancer Center, Columbus, OH, USA., Lute K, Kocak E, Abdessalam S, Yin L, Li O, Guan Z, Philips G, Zheng P, Liu Y

Publikováno v: Blood [Blood] 2007 Jan 01; Vol. 109 (1), pp. 253-8. Date of Electronic Publication: 2006 Aug 08.

Human CTLA4 knock-in mice unravel the quantitative link between tumor immunity and autoimmunity induced by anti-CTLA-4 antibodies.

Autor: Lute KD; Division of Cancer Immunology, Department of Pathology, Center for Biostatistics, Columbus, OH, USA., May KF Jr, Lu P, Zhang H, Kocak E, Mosinger B, Wolford C, Phillips G, Caligiuri MA, Zheng P, Liu Y

Publikováno v: Blood [Blood] 2005 Nov 01; Vol. 106 (9), pp. 3127-33. Date of Electronic Publication: 2005 Jul 21.

Failed adoptive immunotherapy with tumor-specific T cells: reversal with low-dose interleukin 15 but not low-dose interleukin 2.

Autor: Roychowdhury S; Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University, Columbus, Ohio 43210, USA., May KF Jr, Tzou KS, Lin T, Bhatt D, Freud AG, Guimond M, Ferketich AK, Liu Y, Caligiuri MA

Publikováno v: Cancer research [Cancer Res] 2004 Nov 01; Vol. 64 (21), pp. 8062-7.