Zobrazeno 1 - 10
of 11
pro vyhledávání: '"May K Wang"'
Autor:
Ricardo Rajsbaum, Randy A Albrecht, May K Wang, Natalya P Maharaj, Gijs A Versteeg, Estanislao Nistal-Villán, Adolfo García-Sastre, Michaela U Gack
Publikováno v:
PLoS Pathogens, Vol 8, Iss 11, p e1003059 (2012)
Influenza A viruses can adapt to new host species, leading to the emergence of novel pathogenic strains. There is evidence that highly pathogenic viruses encode for non-structural 1 (NS1) proteins that are more efficient in suppressing the host immun
Externí odkaz:
https://doaj.org/article/68e798ffdedb4154898c30314604fbb4
Autor:
Dhiraj Acharya, Rebecca Reis, Meta Volcic, GuanQun Liu, May K. Wang, Bing Shao Chia, Rayhane Nchioua, Rüdiger Groß, Jan Münch, Frank Kirchhoff, Konstantin M.J. Sparrer, Michaela U. Gack
Publikováno v:
Cell. 185(19)
The current dogma of RNA-mediated innate immunity is that sensing of immunostimulatory RNA ligands is sufficient for the activation of intracellular sensors and induction of interferon (IFN) responses. Here, we report that actin cytoskeleton disturba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c08250dcb9fc5dd74ff56ed0f77ce70
https://pubmed.ncbi.nlm.nih.gov/36175502
https://pubmed.ncbi.nlm.nih.gov/36175502
Autor:
Thomas J. Hayman, Jian-Guo Zhang, Nadia J. Kershaw, Tatiana B. Kolesnik, Nicos A. Nicola, Seth L. Masters, Michaela U. Gack, Jessica J. Chiang, Sandra E. Nicholson, Edmond M. Linossi, Laura F. Dagley, May K. Wang, James M. Murphy, Michael D. W. Griffin, Jeffrey J. Babon, Akshay A. D’Cruz
Publikováno v:
Biochemical Journal. 475:429-440
The retinoic acid-inducible gene-I (RIG-I) receptor recognizes short 5′-di- and triphosphate base-paired viral RNA and is a critical mediator of the innate immune response against viruses such as influenza A, Ebola, HIV and hepatitis C. This respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798397e94e702c0bf6ce404947881d06
https://doi.org/10.1042/bcj20170427
https://doi.org/10.1042/bcj20170427
Publikováno v:
Cell Host & Microbe. 21:367-375
Ebola virus (EBOV) infection is characterized by sporadic outbreaks caused by zoonotic transmission. Fixed changes in amino acid sequence, such as A82V in the EBOV glycoprotein (GP) that occurred early in the 2013-16 epidemic, are suspected to confer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070aa87598898e759000547c36f0953f
https://doi.org/10.1016/j.chom.2017.02.002
https://doi.org/10.1016/j.chom.2017.02.002
Autor:
Jessica J. Chiang, May K. Wang, Michaela U. Gack, Nadia J. Kershaw, Nicos A. Nicola, Jeffrey J. Babon, Akshay A. D’Cruz, Sandra E. Nicholson
Publikováno v:
Biochemical Journal. 456:231-240
TRIM (tripartite motif) proteins primarily function as ubiquitin E3 ligases that regulate the innate immune response to infection. TRIM25 [also known as Efp (oestrogen-responsive finger protein)] has been implicated in the regulation of oestrogen rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098f69647430f675c7c32f6b6b856a62
https://doi.org/10.1042/bj20121425
https://doi.org/10.1042/bj20121425
Autor:
Sebastian Gableske, Teunis B. H. Geijtenbeek, Michaela U. Gack, May K. Wang, Florian Full, Linda J. Rennick, Annelies W. Mesman, W. Paul Duprex, Sonja I. Gringhuis, Meredith Davis
Publikováno v:
Cell host & microbe, 16(1), 19-30. Cell Press
The cytosolic sensor MDA5 is crucial for antiviral innate immune defense against various RNA viruses including measles virus; as such, many viruses have evolved strategies to antagonize the antiviral activity of MDA5. Here, we show that measles virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffbb3aa23fceda3c000f88c21f74c9c
https://europepmc.org/articles/PMC4120867/
https://europepmc.org/articles/PMC4120867/
Autor:
Eva-Katharina Pauli, Katharina F. Feister, Michaela U. Gack, Sebastian Gableske, Meredith Davis, May K. Wang, Ying Kai Chan
Publikováno v:
Science Signaling. 7
Ubiquitylation is an important mechanism for regulating innate immune responses to viral infections. Attachment of lysine 63 (Lys(63))-linked ubiquitin chains to the RNA sensor retinoic acid-inducible gene-I (RIG-I) by the ubiquitin E3 ligase tripart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30e5bd6b7aa43832dc1c91f1c5fe297
https://doi.org/10.1126/scisignal.2004577
https://doi.org/10.1126/scisignal.2004577
Autor:
Akshay A. D’Cruz, Laura F. Dagley, Jessica J. Chiang, Nadia J. Kershaw, Edmond M. Linossi, Jian-Guo Zhang, Jeffrey J. Babon, Michaela U. Gack, May K. Wang, Nicos A. Nicola, Ben A. Croker, Sandra E. Nicholson
Publikováno v:
Blood. 124:1580-1580
SPRY/B30.2 domain-containing proteins are found in 103 human proteins that regulate numerous cellular processes including RNA processing, histone methylation, red blood cell membrane integrity, terminal erythroid cell differentiation and innate immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d293e71ca25ceda59daa224d12b78ce4
https://doi.org/10.1182/blood.v124.21.1580.1580
https://doi.org/10.1182/blood.v124.21.1580.1580
Autor:
Effi Wies, Shenghua Zhou, Natalya P. Maharaj, Robert W. Finberg, Michaela U. Gack, May K. Wang, Kan Chen
Publikováno v:
Cytokine. 63:309
Innate sensing of viral infection and the subsequent activation of signaling pathways are essential for an effective antiviral immune response. Retinoic acid-inducible gene-I (RIG-I; also called DDX58) and melanoma differentiation-associated gene 5 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b55440d15db3872be4c940ba89ce31f8
https://doi.org/10.1016/j.cyto.2013.06.283
https://doi.org/10.1016/j.cyto.2013.06.283
Autor:
Estanislao Nistal-Villán, Gijs A. Versteeg, Randy A. Albrecht, May K. Wang, Natalya P. Maharaj, Michaela U. Gack, Adolfo García-Sastre, Ricardo Rajsbaum
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 8, Iss 11, p e1003059 (2012)
PLoS Pathogens, Vol 8, Iss 11, p e1003059 (2012)
Influenza A viruses can adapt to new host species, leading to the emergence of novel pathogenic strains. There is evidence that highly pathogenic viruses encode for non-structural 1 (NS1) proteins that are more efficient in suppressing the host immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f9e33d8e98dbc2615657c6cbc66015
https://doi.org/10.1371/journal.ppat.1003059
https://doi.org/10.1371/journal.ppat.1003059