Zobrazeno 1 - 10
of 240
pro vyhledávání: '"May Griffith"'
Autor:
Egidijus Simoliunas, Inés Ruedas-Torres, Yolanda Jiménez-Gómez, Elle Edin, Mozhgan Aghajanzadeh-Kiyaseh, Mostafa Zamani-Roudbaraki, Rimvydas Asoklis, Milda Alksne, Neethi C. Thathapudi, Bijay K. Poudel, Ieva Rinkunaite, Kasparas Asoklis, Monika Iesmantaite, Laura Ortega-Llamas, Almantas Makselis, Marcelo Munoz, Daiva Baltriukiene, Virginija Bukelskiene, Jaime Gómez-Laguna, Miguel González-Andrades, May Griffith
Publikováno v:
npj Regenerative Medicine, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Pathophysiologic inflammation, e.g., from HSV-1 viral infection, can cause tissue destruction resulting in ulceration, perforation, and ultimately blindness. We developed an injectable Cornea-in-a-Syringe (CIS) sealant-filler to treat damage
Externí odkaz:
https://doaj.org/article/1b496cbaf026441686aba5c8afa0eacd
Autor:
Neethi C. Thathapudi, Natalia Callai-Silva, Kamal Malhotra, Sankar Basu, Mozhgan Aghajanzadeh-Kiyaseh, Mostafa Zamani-Roudbaraki, Marc Groleau, Félix Lombard-Vadnais, Sylvie Lesage, May Griffith
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Corneal HSV-1 infections are a leading cause of infectious blindness globally by triggering tissue damage due to the intense inflammation. HSV-1 infections are treated mainly with antiviral drugs that clear the infections but are inefficient
Externí odkaz:
https://doaj.org/article/6452d8bd7646481ea74da74285fad36f
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/8163df6c81114cce8f5a4b3350adcf06
Autor:
Neethi C. Thathapudi, Marc Groleau, Delali S. Degué, Mozhgan Aghajanzadeh Kiyaseh, Piotr Kujawa, Fouzia Soulhi, Naoufal Akla, May Griffith, Marie-Claude Robert
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Moderate corneal alkali burns such as those sustained from accidental exposure to household chemicals are treated with topical corticosteroids. Side effects include increased intraocular pressure and slowing of wound healing. Here, we c
Externí odkaz:
https://doaj.org/article/1a742e5855f14e0fab4083aa899f99b0
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/a7605c92c18b476aa7334e809ead6fcd
Autor:
Kamal Malhotra, Oleksiy Buznyk, Mohammad Mirazul Islam, Elle Edin, Sankar Basu, Marc Groleau, Delali Shana Dégué, Per Fagerholm, Adrien Fois, Sylvie Lesage, Jaganmohan R. Jangamreddy, Egidijus Šimoliūnas, Aneta Liszka, Hirak K. Patra, May Griffith
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1658 (2023)
Severe HSV-1 infection can cause blindness due to tissue damage from severe inflammation. Due to the high risk of graft failure in HSV-1-infected individuals, cornea transplantation to restore vision is often contraindicated. We tested the capacity f
Externí odkaz:
https://doaj.org/article/ead5572e2f674c328e776c27f4f02836
Autor:
Fiona C. Simpson, Mohammed Mirazul Islam, Oleksiy Buznyk, Elle Edin, Marc Groleau, Monika Kozak-Ljunggren, Federica M. Magrelli, Dina B. AbuSamra, Pablo Argüeso, James Chodosh, Aneta Liszka, Per Fagerholm, May Griffith
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Sterilization of biodegradable, collagen-based implants is challenging as irradiation sterilization methods can alter their mechanical properties. Electron beam (EB) irradiation is a terminal sterilization method that has been used for biologically-d
Externí odkaz:
https://doaj.org/article/cb497156d0fa40958596512b9786d7e0
Autor:
Fiona C. Simpson, Christopher D. McTiernan, Mohammad Mirazul Islam, Oleksiy Buznyk, Philip N. Lewis, Keith M. Meek, Michel Haagdorens, Cindy Audiger, Sylvie Lesage, François-Xavier Gueriot, Isabelle Brunette, Marie-Claude Robert, David Olsen, Laura Koivusalo, Aneta Liszka, Per Fagerholm, Miguel Gonzalez-Andrades, May Griffith
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Simpson, McTiernan et al. develop fully synthetic corneal implants. The resulting CLP-PEG-MPC implants show reduced corneal swelling, haze, and neovascularization compared to CLP-PEG only implants when grafted into a mini-pig cornea alkali burn model
Externí odkaz:
https://doaj.org/article/da52745a8e174b3fb69db4effa395084
Autor:
Alejandro Juarez, Mohamed Djallali, Marilyse Piché, Mathieu Thériault, Marc Groleau, Sharifa Beroual, Christopher D. McTiernan, Grace Lin, Pierre Hélie, Michel Carrier, May Griffith, Isabelle Brunette
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Purpose: To evaluate long-term in vivo functionality of corneas regenerated using a cell-free, liquid hydrogel filler (LiQD Cornea) after deep corneal trauma in the feline model.Methods: Two healthy cats underwent 4 mm diameter stepwise 250/450 µm d
Externí odkaz:
https://doaj.org/article/f2da121cb57c44fea5c592e32b421af5
Autor:
Katiane Roversi, Natalia Callai-Silva, Karine Roversi, May Griffith, Christos Boutopoulos, Rui Daniel Prediger, Sébastien Talbot
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Parkinson’s disease (PD) is the second most common neurodegenerative disorder, affecting 1–2% of the population aged 65 and over. Additionally, non-motor symptoms such as pain and gastrointestinal dysregulation are also common in PD. These impair
Externí odkaz:
https://doaj.org/article/2b75063e3eb14437a175729816bf73c6