Zobrazeno 1 - 10
of 12
pro vyhledávání: '"May F. Mrad"'
Autor:
Ghewa A El-Achkar, May F Mrad, Charbel A Mouawad, Bassam Badran, Ayad A Jaffa, Roberto Motterlini, Eva Hamade, Aida Habib
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216405 (2019)
Statins exert pleiotropic and beneficial anti-inflammatory and antioxidant effects. We have previously reported that macrophages treated with statins increased the expression of heme oxygenase-1 (HO-1), an inducible anti-inflammatory and cytoprotecti
Externí odkaz:
https://doaj.org/article/ded259c09c424fb8a8e4bbc6cd78caa3
Autor:
Charbel A Mouawad, May F Mrad, Moustafa Al-Hariri, Hiba Soussi, Eva Hamade, Jawed Alam, Aïda Habib
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64092 (2013)
The effect of statins on heme oxygenase-1 (HO-1) was compared in 2 murine cell lines, RAW 264.7 and J774A.1 cell lines, and in primary peritoneal macrophages of BALB/c or C57BL/6 mice. The role of endogenous nitric oxide and the type of transcription
Externí odkaz:
https://doaj.org/article/358e58fbe85a4f5493e03b09c0c69b6f
Publikováno v:
Clinical Immunology. 181:9-15
We aimed to investigate the immunologic effects of vitamin D replacement in RRMS patients. In a controlled single center study, patients deficient in 25-hydroxyvitamin D (serum level 35 ng/ml) were followed for the same period. Assessments were perfo
Autor:
Bassam Badran, Eva Hamade, May F. Mrad, Charbel A. Mouawad, Aida Habib, Ayad A. Jaffa, Ghewa A. El-Achkar, Roberto Motterlini
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2019, 14 (5), pp.e0216405. ⟨10.1371/journal.pone.0216405⟩
PLoS ONE, Vol 14, Iss 5, p e0216405 (2019)
PLoS ONE, 2019, 14 (5), pp.e0216405. ⟨10.1371/journal.pone.0216405⟩
PLoS ONE, Public Library of Science, 2019, 14 (5), pp.e0216405. ⟨10.1371/journal.pone.0216405⟩
PLoS ONE, Vol 14, Iss 5, p e0216405 (2019)
PLoS ONE, 2019, 14 (5), pp.e0216405. ⟨10.1371/journal.pone.0216405⟩
International audience; Statins exert pleiotropic and beneficial anti-inflammatory and antioxidant effects. We have previously reported that macrophages treated with statins increased the expression of heme oxygenase-1 (HO-1), an inducible anti-infla
Autor:
Ghewa A. El-Achkar, Georges Nemer, Christophe Créminon, Aida Habib, Charbel A. Mouawad, Sophie Lotersztajn, May F. Mrad, Ali A. Abdul-Sater
Publikováno v:
Journal of Cellular Biochemistry. 117:1176-1186
Statins have been shown to exert anti-inflammatory and anti-fibrogenic properties in the liver. In the present study, we explored the mechanisms underlying anti-fibrogenic effects of statins in isolated hepatic myofibroblasts and focused on cyclooxye
Publikováno v:
Clinical immunology (Orlando, Fla.).
Vitamin D is a secosteroid hormone that plays an important regulatory role in calcium homeostasis and bone metabolism. Immune cells can both produce and respond to 1,25(OH)2D3. CD4+ T cells from vitamin D receptor (VDR) KO mice produce higher levels
Autor:
Charbel A, Mouawad, May F, Mrad, Ghewa A, El-Achkar, Ali, Abdul-Sater, Georges M, Nemer, Christophe, Creminon, Sophie, Lotersztajn, Aïda, Habib
Publikováno v:
Journal of cellular biochemistry. 117(5)
Statins have been shown to exert anti-inflammatory and anti-fibrogenic properties in the liver. In the present study, we explored the mechanisms underlying anti-fibrogenic effects of statins in isolated hepatic myofibroblasts and focused on cyclooxye
Autor:
Raghida Abou Merhi, Bassam Badran, Assaad A. Eid, Eva Hamade, Taghreed Hirz, Soukaina Hammoud, Ali Hachem, Aida Habib, Ali Khalaf, Mariam Jouni, Nehme El Hachem, May F. Mrad, Ghewa A. El-Achkar, Hussein Fayyad-Kazan
Publikováno v:
European journal of pharmacology. 750
Cyclooxygenases (COXs) are important membrane-bound heme containing enzymes important in platelet activation and inflammation. COX-1 is constitutively expressed in most cells whereas COX-2 is an inducible isoform highly expressed in inflammatory cond
Autor:
May F. Mrad, Charbel A. Mouawad, Hiba Soussi, Jawed Alam, Eva Hamade, Moustafa Al-Hariri, Aida Habib
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64092 (2013)
PLoS ONE
PLoS ONE
The effect of statins on heme oxygenase-1 (HO-1) was compared in 2 murine cell lines, RAW 264.7 and J774A.1 cell lines, and in primary peritoneal macrophages of BALB/c or C57BL/6 mice. The role of endogenous nitric oxide and the type of transcription
Publikováno v:
Journal of cellular biochemistry. 113(11)
Statins, inhibitors of HMG CoA reductase, have pleiotropic effects independent of their capacity to lower cholesterol. Heme-oxygenase-1(HO-1) plays an important role as an anti-oxidant and anti-inflammatory enzyme. In the present study, we used NIH 3