Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in α-tubulin

Autor: Loganzo, F., Hari, M., Annable, T., Tan, X., Morilla, D. B., Musto, S., Arie Zask, Kaplan, J., Minnick Jr, A. A., May, M. K., Ayral-Kaloustian, S., Poruchynsky, M. S., Fojo, T., Greenberger, L. M.

Publikováno v: Scopus-Elsevier

HTI-286, a synthetic analogue of hemiasterlin, depolymerizes microtubules and is proposed to bind at the Vinca peptide site in tubulin. It has excellent in vivo antitumor activity in human xenograft models, including tumors that express P-glycoprotei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5224eb821656694daff79100c1a2bbbe
https://doi.org/10.1158/1535-7163.1319.3.10

Synthesis of carbon-14 and carbon-13 labeled 3-methyl-6-[3-(trifluoro-methyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine.

Autor: May, M. K., Lanzilotti, A. E.

Publikováno v: Journal of Labelled Compounds & Radiopharmaceuticals; May1984, Vol. 21 Issue 5, p489-492, 4p

Irreversible inhibition of epidermal growth factor receptor tyrosine kinase with in vivo activity by N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-2-butynamide (CL-387,785)

Autor: Discafani, C. M., Carroll, M. L., Floyd, M. B., Hollander, I. J., Husain, Z., Johnson, B. D., Kitchen, D., May, M. K., Malo, M. S., Minnick, A. A.

Publikováno v: Biochemical Pharmacology; 1999, Vol. 57 Issue: 8 p917-926, 10p

Outbreak of nonfermentative Gram-negative bacteria (Ralstonia pickettii and Stenotrophomonas maltophilia) in a hemodialysis center.

Autor: K Thet M; Department of Renal Medicine, RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam., Pelobello MLF; Department of Renal Medicine, RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam., Das M; Department of Renal Medicine, RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam., Alhaji MM; PAPRSB Institute of Health Sciences, Universiti Brunei Darussalam, Brunei Darussalam., Chong VH; Department of Medicine, RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam., Khalil MAM; Department of Renal Medicine, RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam., Chinniah T; Department of Microbiology, RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam., Tan J; PAPRSB Institute of Health Sciences, Universiti Brunei Darussalam, Brunei Darussalam.

Publikováno v: Hemodialysis international. International Symposium on Home Hemodialysis [Hemodial Int] 2019 Jul; Vol. 23 (3), pp. E83-E89. Date of Electronic Publication: 2019 Feb 12.

Prenatal neurogenesis in the septal region of the rat.

Autor: Lawson SN, May MK, Williams TH

Publikováno v: Brain research [Brain Res] 1977 Jun 24; Vol. 129 (1), pp. 147-51.