Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Maxwell T, Laws"'
Autor:
Maxwell T. Laws, Erin N. Walker, Francesca M. Cozzi, Leonel Ampie, Mi-Yeon Jung, Eric C. Burton, Desmond A. Brown
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Glioblastoma is the most common, malignant primary brain tumor in adults and remains universally fatal. While immunotherapy has vastly improved the treatment of several solid cancers, efficacy in glioblastoma is limited. These challenges are due in p
Externí odkaz:
https://doaj.org/article/e1b75d04834e44bca78d4ca7eb854df4
Autor:
Thomas J. Mangner, Xin Lu, Maxwell T. Laws, Shreya Potukutchi, Jeremy T Llaniguez, David Gelovani, Robin E. Bonomi, Juri G. Gelovani, Swatabdi Kamal
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
HDAC class IIa enzymes (HDAC4, 5, 7, 9) are important for glioma progression, invasion, responses to TMZ and radiotherapy, and prognosis. In this study, we demonstrated the efficacy of PET/CT/(MRI) with [18F]TFAHA for non-invasive and quantitative im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::087b945966379f123b016a373af8411d
http://link.springer.com/article/10.1038/s41598-019-40054-2
http://link.springer.com/article/10.1038/s41598-019-40054-2
Autor:
Darius Ansari, Stephen J. Bordes, Halle E.K. Burley, Christopher E. Childers, Beom Sun Chung, Mary Katherine Cleveland, Graham Dupont, Daniel T. Ginat, Dia R. Halalmeh, Shiwei Huang, Joe Iwanaga, Andrew Jack, Skyler Jenkins, Ari D. Kappel, Bradely Kolb, Maxwell T. Laws, Mishan Listmann, Karishma Mehta, Marc D. Moisi, Seong-Jin Moon, Peter Oakes, Rod J. Oskouian, Felipe H. Sanders, R. Shane Tubbs, Zane Tymchack, Alexander von Glinski, Lauren Wahl, Tyler Warner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82972f7ca58aea9e6f93f4a89d33787e
https://doi.org/10.1016/b978-0-323-67376-1.01002-8
https://doi.org/10.1016/b978-0-323-67376-1.01002-8
Autor:
Xin Lu, Otto Muzik, Thomas J. Mangner, Aleksandr Shavrin, Vadim V. Popov, Maxwell T. Laws, David Gelovani, Robin E. Bonomi, Anjoy Majhi, Renshyan Liu, Juri G. Gelovani, Nashaat Turkman
Publikováno v:
Journal of Medicinal Chemistry. 61:7116-7130
Sirtuin 1 (SIRT1) is a class III histone deacetylase that plays significant roles in the regulation of lifespan, metabolism, memory, and circadian rhythms and in the mechanisms of many diseases. However, methods of monitoring the pharmacodynamics of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e2d5e67a904b5be243b262d3ede9765
https://doi.org/10.1021/acs.jmedchem.8b00253
https://doi.org/10.1021/acs.jmedchem.8b00253
Autor:
Xin Lu, Thomas J. Mangner, Jeremy T Llaniguez, Maxwell T. Laws, David Gelovani, Robin E. Bonomi, Juri G. Gelovani
Publikováno v:
Neuro-Oncology Advances
Background Several studies demonstrated that glioblastoma multiforme progression and recurrence is linked to epigenetic regulatory mechanisms. Sirtuin 1 (SIRT1) plays an important role in glioma progression, invasion, and treatment response and is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f1238b1bf236fb86864028eae18a2c
https://doi.org/10.1093/noajnl/vdaa006
https://doi.org/10.1093/noajnl/vdaa006
Autor:
Wei Chen, Rafael Ramos, Hui Li, Luke D Wesemann, Xi Zhou, Baiqi Zhu, Jianbo Shao, Jun Xia, Maxwell T. Laws, Huijing Ma, Jiani Hu, Jie Tian
Publikováno v:
BMC medicine, 18(1):123
BMC Medicine
BMC Medicine, Vol 18, Iss 1, Pp 1-11 (2020)
BMC Medicine
BMC Medicine, Vol 18, Iss 1, Pp 1-11 (2020)
BackgroundCompared to adults, there are relatively few studies on COVID-19 infection in children, and even less focusing on the unique features of COVID-19 in children in terms of laboratory findings, locations of computerized tomography (CT) lesions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1983d7a529454f175fd2b3fb21bf56d
https://repository.publisso.de/resource/frl:6420817
https://repository.publisso.de/resource/frl:6420817
Autor:
Jie Tian, Jun Xia, Maxwell T. Laws, Wei Chen, Rafael Ramos, Huijing Ma, Hui Li, Xi Zhou, Jiani Hu, Jianbo Shao, Luke D Wesemann, Baiqi Zhu
Publikováno v:
SSRN Electronic Journal.
Background: Few studies have comprehensively examined COVID-19 infection in children Consequently, several important clinical questions remain unanswered br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6edae3671862f3b275e868ac07a0dd
https://doi.org/10.2139/ssrn.3556676
https://doi.org/10.2139/ssrn.3556676
This chapter describes the technical aspects of the transpleural and retropleural approaches and then compares the two approaches in terms of surgical considerations and resultant patient outcomes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::115423269780851ee5b6b5b415673c25
https://doi.org/10.1016/b978-0-323-67376-1.00022-7
https://doi.org/10.1016/b978-0-323-67376-1.00022-7
Autor:
Robin, Bonomi, Vadim, Popov, Maxwell T, Laws, David, Gelovani, Anjoy, Majhi, Aleksandr, Shavrin, Xin, Lu, Otto, Muzik, Nashaat, Turkman, Renshyan, Liu, Thomas, Mangner, Juri G, Gelovani
Publikováno v:
Journal of medicinal chemistry. 61(16)
Sirtuin 1 (SIRT1) is a class III histone deacetylase that plays significant roles in the regulation of lifespan, metabolism, memory, and circadian rhythms and in the mechanisms of many diseases. However, methods of monitoring the pharmacodynamics of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5af3a4f5f971c522d4b147aa9546cdc
https://pubmed.ncbi.nlm.nih.gov/30052441
https://pubmed.ncbi.nlm.nih.gov/30052441
Autor:
Swatabdi Kamal, Thomas J. Mangner, Maxwell T. Laws, Xin Lu, Srinivasu Kallakuri, Juri G. Gelovani, Vadim V. Popov, Jeremy Llanguez, Robin E. Bonomi, David Gelovani
Publikováno v:
Cancer Research. 76:3976-3976
Histone deacetylases (HDACs) are involved in the pathogenesis of cancer through modulation of the expression of various genes involved in cellular proliferation, migration, angiogenesis and apoptosis. HDAC class IIa enzymes interact with tumor suppre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df8093c9a803dad29341a806f959fec0
https://doi.org/10.1158/1538-7445.am2016-3976
https://doi.org/10.1158/1538-7445.am2016-3976