Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Maxwell R Lloyd"'
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Endocrine therapy (ET) is a pivotal strategy to manage early- and advanced-stage estrogen receptor-positive (ER+) breast cancer. In patients with metastatic breast cancer (MBC), progression of disease inevitably occurs due to the presence of acquired
Externí odkaz:
https://doaj.org/article/1b8d6b8ced144234831b1782a1f23ccb
Autor:
Maxwell R. Lloyd, Lianne Ryan, Arielle J. Medford, Jennifer C. Keenan, Laura M. Spring, Neelima Vidula, Beverly Moy, Dejan Juric, Leif Ellisen, Aditya Bardia, Seth A. Wander
Publikováno v:
Cancer Research. 83:P1-13
Background: CDK4/6 inhibitors (CDK4/6i) are standard of care for the management of HR+/HER2- metastatic breast cancer (MBC). Genomic alterations that drive resistance to CDK4/6i are diverse, and while the molecular landscape is heterogeneous, several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad1db1dce3741f5fc106e167e54a45a0
https://doi.org/10.1158/1538-7445.sabcs22-p1-13-07
https://doi.org/10.1158/1538-7445.sabcs22-p1-13-07
Autor:
Jamie O. Brett, Taronish D. Dubash, Gabriela N. Johnson, Andrzej Niemierko, Veronica Mariotti, Leslie S.L. Kim, Jing Xi, Apurva Pandey, Siobhan Dunne, Azadeh Nasrazadani, Maxwell R. Lloyd, Avinash Kambadakone, Laura M. Spring, Douglas S. Micalizzi, Maristela L. Onozato, Dante Che, Utthara Nayar, Adam Brufsky, Kevin Kalinsky, Cynthia X. Ma, Joyce O'Shaughnessy, Hyo S. Han, Anthony J. Iafrate, Lianne Y. Ryan, Dejan Juric, Beverly Moy, Leif W. Ellisen, Shyamala Maheswaran, Nikhil Wagle, Daniel A. Haber, Aditya Bardia, Seth A. Wander
Publikováno v:
JCO Precision Oncology.
PURPOSE For patients with hormone receptor–positive (HR+), human epidermal growth factor receptor 2–negative (HER2–) metastatic breast cancer (MBC), first-line treatment is endocrine therapy (ET) plus cyclin-dependent kinase 4/6 inhibition (CDK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d71e37d64119ddab4b4e8fa6a1cff101
https://doi.org/10.1200/po.22.00532
https://doi.org/10.1200/po.22.00532
Autor:
Nikhil Wagle, Sean G. Buchanan, Nancy U. Lin, Sara M. Tolaney, Eric P. Winer, Levi A. Garraway, Jill D. Kremer, Melissa E. Hughes, Gerald Batist, Quincy S. Chu, Gerard J. Oakley, Patricia S. Smith, John R. Stille, Valerie M. Jansen, Chunping Yu, Xiang S. Ye, Lacey M. Litchfield, Ricardo Martinez, Stephen H. Parsons, Adrienne G. Waks, Utthara Nayar, Kailey J. Kowalski, Karla Helvie, Pingping Mao, Flora Luo, Dewey Kim, Maxwell R. Lloyd, Jorge E. Buendia-Buendia, Gabriela N. Johnson, Xueqian Gong, Ofir Cohen, Seth A. Wander
Figure S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4429c0b5f6674a0a879dccdfd024b9
https://doi.org/10.1158/2159-8290.22535354.v1
https://doi.org/10.1158/2159-8290.22535354.v1
Autor:
Nikhil Wagle, Sean G. Buchanan, Nancy U. Lin, Sara M. Tolaney, Eric P. Winer, Levi A. Garraway, Jill D. Kremer, Melissa E. Hughes, Gerald Batist, Quincy S. Chu, Gerard J. Oakley, Patricia S. Smith, John R. Stille, Valerie M. Jansen, Chunping Yu, Xiang S. Ye, Lacey M. Litchfield, Ricardo Martinez, Stephen H. Parsons, Adrienne G. Waks, Utthara Nayar, Kailey J. Kowalski, Karla Helvie, Pingping Mao, Flora Luo, Dewey Kim, Maxwell R. Lloyd, Jorge E. Buendia-Buendia, Gabriela N. Johnson, Xueqian Gong, Ofir Cohen, Seth A. Wander
Mechanisms driving resistance to cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) in hormone receptor–positive (HR+) breast cancer have not been clearly defined. Whole-exome sequencing of 59 tumors with CDK4/6i exposure revealed multiple candidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89133c0f6a6b34907466acc61efd6697
https://doi.org/10.1158/2159-8290.c.6547832.v1
https://doi.org/10.1158/2159-8290.c.6547832.v1
Autor:
Nikhil Wagle, Sean G. Buchanan, Nancy U. Lin, Sara M. Tolaney, Eric P. Winer, Levi A. Garraway, Jill D. Kremer, Melissa E. Hughes, Gerald Batist, Quincy S. Chu, Gerard J. Oakley, Patricia S. Smith, John R. Stille, Valerie M. Jansen, Chunping Yu, Xiang S. Ye, Lacey M. Litchfield, Ricardo Martinez, Stephen H. Parsons, Adrienne G. Waks, Utthara Nayar, Kailey J. Kowalski, Karla Helvie, Pingping Mao, Flora Luo, Dewey Kim, Maxwell R. Lloyd, Jorge E. Buendia-Buendia, Gabriela N. Johnson, Xueqian Gong, Ofir Cohen, Seth A. Wander
Figure S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015e896eb128c33df61fd5df03da0d7d
https://doi.org/10.1158/2159-8290.22535357
https://doi.org/10.1158/2159-8290.22535357
Autor:
Nikhil Wagle, Sean G. Buchanan, Nancy U. Lin, Sara M. Tolaney, Eric P. Winer, Levi A. Garraway, Jill D. Kremer, Melissa E. Hughes, Gerald Batist, Quincy S. Chu, Gerard J. Oakley, Patricia S. Smith, John R. Stille, Valerie M. Jansen, Chunping Yu, Xiang S. Ye, Lacey M. Litchfield, Ricardo Martinez, Stephen H. Parsons, Adrienne G. Waks, Utthara Nayar, Kailey J. Kowalski, Karla Helvie, Pingping Mao, Flora Luo, Dewey Kim, Maxwell R. Lloyd, Jorge E. Buendia-Buendia, Gabriela N. Johnson, Xueqian Gong, Ofir Cohen, Seth A. Wander
Figure S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001f147702d0ceaf79fb4c743f76c6cc
https://doi.org/10.1158/2159-8290.22535366
https://doi.org/10.1158/2159-8290.22535366
Autor:
Nikhil Wagle, Sean G. Buchanan, Nancy U. Lin, Sara M. Tolaney, Eric P. Winer, Levi A. Garraway, Jill D. Kremer, Melissa E. Hughes, Gerald Batist, Quincy S. Chu, Gerard J. Oakley, Patricia S. Smith, John R. Stille, Valerie M. Jansen, Chunping Yu, Xiang S. Ye, Lacey M. Litchfield, Ricardo Martinez, Stephen H. Parsons, Adrienne G. Waks, Utthara Nayar, Kailey J. Kowalski, Karla Helvie, Pingping Mao, Flora Luo, Dewey Kim, Maxwell R. Lloyd, Jorge E. Buendia-Buendia, Gabriela N. Johnson, Xueqian Gong, Ofir Cohen, Seth A. Wander
Figure S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ed46edadca7e07fadb84a63501aae8
https://doi.org/10.1158/2159-8290.22535369
https://doi.org/10.1158/2159-8290.22535369
Autor:
Nikhil Wagle, Sean G. Buchanan, Nancy U. Lin, Sara M. Tolaney, Eric P. Winer, Levi A. Garraway, Jill D. Kremer, Melissa E. Hughes, Gerald Batist, Quincy S. Chu, Gerard J. Oakley, Patricia S. Smith, John R. Stille, Valerie M. Jansen, Chunping Yu, Xiang S. Ye, Lacey M. Litchfield, Ricardo Martinez, Stephen H. Parsons, Adrienne G. Waks, Utthara Nayar, Kailey J. Kowalski, Karla Helvie, Pingping Mao, Flora Luo, Dewey Kim, Maxwell R. Lloyd, Jorge E. Buendia-Buendia, Gabriela N. Johnson, Xueqian Gong, Ofir Cohen, Seth A. Wander
Supplemental Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2a1eb9d4455cab57a52e926b75efc3
https://doi.org/10.1158/2159-8290.22535351.v1
https://doi.org/10.1158/2159-8290.22535351.v1
Autor:
Nikhil Wagle, Sean G. Buchanan, Nancy U. Lin, Sara M. Tolaney, Eric P. Winer, Levi A. Garraway, Jill D. Kremer, Melissa E. Hughes, Gerald Batist, Quincy S. Chu, Gerard J. Oakley, Patricia S. Smith, John R. Stille, Valerie M. Jansen, Chunping Yu, Xiang S. Ye, Lacey M. Litchfield, Ricardo Martinez, Stephen H. Parsons, Adrienne G. Waks, Utthara Nayar, Kailey J. Kowalski, Karla Helvie, Pingping Mao, Flora Luo, Dewey Kim, Maxwell R. Lloyd, Jorge E. Buendia-Buendia, Gabriela N. Johnson, Xueqian Gong, Ofir Cohen, Seth A. Wander
Figure S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720e9871d01381786cc6616e6ea1e874
https://doi.org/10.1158/2159-8290.22535360.v1
https://doi.org/10.1158/2159-8290.22535360.v1