Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Maxwell P. Lee"'
Autor:
Fatao Liu, Nan Hu, Kewei Jiang, Huaitian Liu, Mingyi Wang, Ying Hu, Tongwu Zhang, Ho-Hsiang Wu, Howard Yang, Hao Weng, Ping Dong, Carol Giffen, Bin Zhu, Maxwell P. Lee, Christian C. Abnet, Philip R. Taylor, Yun Liu, Yingbin Liu, Alisa M. Goldstein
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Gastric cancer (GC), a molecularly heterogeneous disease, is the third leading cause of cancer death worldwide. The majority of GC cases worldwide occur in East Asia, predominantly China. Mutational Signature Framework offers an e
Externí odkaz:
https://doaj.org/article/959218a62fb5456682653adbb47e9cf6
Autor:
Megan R. Majocha, Devin E. Jackson, Ngoc-Han Ha, Ruhul Amin, Marie Pangrácová, Christina R. Ross, Howard H. Yang, Maxwell P. Lee, Kent W. Hunter
Publikováno v:
PLoS Genetics, Vol 20, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/bb60baf337b54d10a9964ebc823c234c
Autor:
Young-Im Kim, Yu-Chou Tseng, Gamze Ayaz, Shasha Wang, Hualong Yan, Wendy du Bois, Howard Yang, Tao Zhen, Maxwell P. Lee, Paul Liu, Rosandra N. Kaplan, Jing Huang
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Background The absence of prominent, actionable genetic alternations in osteosarcomas (OS) implies that transcriptional and epigenetic mechanisms significantly contribute to the progression of this life-threatening form of cancer. Therefore,
Externí odkaz:
https://doaj.org/article/2dca3bb9b8194d338a190bb1d82ddccc
Autor:
Ruhul Amin, Anjali Shukla, Jacqueline Jufen Zhu, Sohyoung Kim, Ping Wang, Simon Zhongyuan Tian, Andy D. Tran, Debasish Paul, Steven D. Cappell, Sandra Burkett, Huaitian Liu, Maxwell P. Lee, Michael J. Kruhlak, Jennifer E. Dwyer, R. Mark Simpson, Gordon L. Hager, Yijun Ruan, Kent W. Hunter
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-23 (2021)
The involvement of nuclear pore proteins in cellular mechanosensing and metastasis is unclear. Here the authors identify that nuclear pore protein NUP210 promotes metastasis through the interaction with mechanotransducer LINC complex protein and chro
Externí odkaz:
https://doaj.org/article/53398503c4ff4121a84866fffaede387
Autor:
Howard Yang, Hua Su, Nan Hu, Chaoyu Wang, Lemin Wang, Carol Giffen, Alisa M. Goldstein, Maxwell P. Lee, Philip R. Taylor
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide and in China. We know miRNAs influence gene expression in tumorigenesis, but it is unclear how miRNAs affect gene expression or influence survi
Externí odkaz:
https://doaj.org/article/7b279539cdab4562aa46ca909ddcee17
Autor:
Kerrie L. Marie, Antonella Sassano, Howard H. Yang, Aleksandra M. Michalowski, Helen T. Michael, Theresa Guo, Yien Che Tsai, Allan M. Weissman, Maxwell P. Lee, Lisa M. Jenkins, M. Raza Zaidi, Eva Pérez-Guijarro, Chi-Ping Day, Kris Ylaya, Stephen M. Hewitt, Nimit L. Patel, Heinz Arnheiter, Sean Davis, Paul S. Meltzer, Glenn Merlino, Pravin J. Mishra
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Metastatic cells can mimic many of the phenotypic behaviors of embryonic cells. Here, the authors generate a melanoblast-specific transcriptome using a genetically engineered mouse model and identify KDELR3 as a pro-metastasis gene in melanoma.
Externí odkaz:
https://doaj.org/article/35727847607f4f45b98d5dc601c357f5
Autor:
Darawalee Wangsa, Rüdiger Braun, Christina H. Stuelten, Markus Brown, Kerry M. Bauer, Georg Emons, Leigh A. Weston, Yue Hu, Howard H. Yang, Maria Vila-Casadesús, Maxwell P. Lee, Philip Brauer, Lidia Warner, Madhvi Upender, Amanda B. Hummon, Jordi Camps, Thomas Ried
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 7, Pp 721-729 (2019)
Chromosomal aneuploidy is a defining feature of epithelial cancers. The pattern of aneuploidies is cancer-type specific. For instance, the gain of chromosome 13 occurs almost exclusively in colorectal cancer. We used microcell-mediated chromosome tra
Externí odkaz:
https://doaj.org/article/423c89043e55402983a7a4b7e01513da
Autor:
Maxwell P. Lee
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Epigenetic information is characterized by its stable transmission during mitotic cell divisions and plasticity during development and differentiation. This duality is in contrast to genetic information, which is stable and identical in all cells in
Externí odkaz:
https://doaj.org/article/db47c137d4c74febbb6ed68a82295124
Autor:
Bih-Rong Wei PhD, Charles H. Halsey DVM, PhD, Shelley B. Hoover BS, Munish Puri PhD, Howard H. Yang PhD, Brandon D. Gallas PhD, Maxwell P. Lee PhD, Weijie Chen PhD, Amy C. Durham MS, VMD, Jennifer E. Dwyer MS, Melissa D. Sánchez VMD, PhD, Ryan P. Traslavina DVM, Chad Frank MS, DVM, Charles Bradley VMD, Lawrence D. McGill DVM, PhD, D. Glen Esplin DVM, PhD, Paula A. Schaffer DVM, MS, Sarah D. Cramer DVM, PhD, L. Tiffany Lyle DVM, PhD, Jessica Beck DVM, Elizabeth Buza DVM, Qi Gong MS, Stephen M. Hewitt MD, PhD, R. Mark Simpson DVM, PhD
Publikováno v:
Academic Pathology, Vol 6 (2019)
Validating digital pathology as substitute for conventional microscopy in diagnosis remains a priority to assure effectiveness. Intermodality concordance studies typically focus on achieving the same diagnosis by digital display of whole slide images
Externí odkaz:
https://doaj.org/article/5fda47df28cb483994b0c7c61cbbc949
Autor:
Can Kızılkale, Farid Rashidi Mehrabadi, Erfan Sadeqi Azer, Eva Pérez-Guijarro, Kerrie L. Marie, Maxwell P. Lee, Chi-Ping Day, Glenn Merlino, Funda Ergün, Aydın Buluç, S. Cenk Sahinalp, Salem Malikić
Publikováno v:
Nature Computational Science. 2:577-583
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::317e8d049c7134341f528e104418646a
https://doi.org/10.1038/s43588-022-00298-x
https://doi.org/10.1038/s43588-022-00298-x