Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Maxwell Lee"'
Autor:
Sara Zahraeifard, Zhiguang Xiao, Jae Young So, Abdul Ahad, Selina Montoya, Woo Yong Park, Trinadharao Sornapudi, Tiffany Andohkow, Abigail Read, Noemi Kedei, Vishal Koparde, Howard Yang, Maxwell Lee, Nathan Wong, Maggie Cam, Kun Wang, Eytan Ruppin, Ji Luo, Christine Hollander, Li Yang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Low response rate, treatment relapse, and resistance remain key challenges for cancer treatment with immune checkpoint blockade (ICB). Here we report that loss of specific tumor suppressors (TS) induces an inflammatory response and promotes
Externí odkaz:
https://doaj.org/article/9768d8da936a47e3adc3b7181439d341
Publikováno v:
BMC Immunology, Vol 23, Iss 1, Pp 1-8 (2022)
Abstract Background Determining T cell responses to naturally processed and presented antigens is a critical immune correlate to determine efficacy of an investigational immunotherapeutic in clinical trials. In most cases, minimal epitopes and HLA re
Externí odkaz:
https://doaj.org/article/6a1a1b5c53d34df78f75b6cfbe7aec53
Autor:
Kirsten L. Viola, Maira A. Bicca, Adrian M. Bebenek, Daniel L. Kranz, Vikas Nandwana, Emily A. Waters, Chad R. Haney, Maxwell Lee, Abhay Gupta, Zachary Brahmbhatt, Weijian Huang, Ting-Tung Chang, Anderson Peck, Clarissa Valdez, Vinayak P. Dravid, William L. Klein
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2022)
Improvements have been made in the diagnosis of Alzheimer’s disease (AD), manifesting mostly in the development of in vivo imaging methods that allow for the detection of pathological changes in AD by magnetic resonance imaging (MRI) and positron e
Externí odkaz:
https://doaj.org/article/20581e62a38f44489be8d498e94566f5
Autor:
Navdeep Malik, Hualong Yan, Nellie Moshkovich, Murali Palangat, Howard Yang, Vanesa Sanchez, Zhuo Cai, Tyler J. Peat, Shunlin Jiang, Chengyu Liu, Maxwell Lee, Beverly A. Mock, Stuart H. Yuspa, Daniel Larson, Lalage M. Wakefield, Jing Huang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
CBFB is highly mutated in breast cancers and is known to interact with RUNX proteins to regulate transcription. Here, the authors describe a non-canonical role of CBFB in translation regulation in which it binds to mRNAs through hnRNPK, facilitating
Externí odkaz:
https://doaj.org/article/3c11e12f7be441d2bf872bf286db67bb
Autor:
Navdeep Malik, Hualong Yan, Howard H Yang, Gamze Ayaz, Wendy DuBois, Yu-Chou Tseng, Young-Im Kim, Shunlin Jiang, Chengyu Liu, Maxwell Lee, Jing Huang
Publikováno v:
PLoS Genetics, Vol 17, Iss 5, p e1009553 (2021)
The CBFB gene is frequently mutated in several types of solid tumors. Emerging evidence suggests that CBFB is a tumor suppressor in breast cancer. However, our understanding of the tumor suppressive function of CBFB remains incomplete. Here, we analy
Externí odkaz:
https://doaj.org/article/bd92132d66e74b4e8fce16a33bde98e7
Autor:
Christina Ross, Karol Szczepanek, Maxwell Lee, Howard Yang, Tinghu Qiu, Jack D Sanford, Kent Hunter
Publikováno v:
PLoS Genetics, Vol 16, Iss 5, p e1008743 (2020)
Metastasis remains the principle cause of mortality for breast cancer and presents a critical challenge because secondary lesions are often refractory to conventional treatments. While specific genetic alterations are tightly linked to primary tumor
Externí odkaz:
https://doaj.org/article/b2d26b3fe05a4ef5a6e2ca77b9382b64
Autor:
Navdeep Malik, Young-Im Kim, Hualong Yan, Yu-Chou Tseng, Wendy du Bois, Gamze Ayaz, Andy D. Tran, Laura Vera-Ramirez, Howard Yang, Aleksandra M. Michalowski, Michael Kruhlak, Maxwell Lee, Kent W. Hunter, Jing Huang
Publikováno v:
Cancer Research. 83:1280-1298
Understanding functional interactions between cancer mutations is an attractive strategy for discovering unappreciated cancer pathways and developing new combination therapies to improve personalized treatment. However, distinguishing driver gene pai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0193cbcaa009ab8c86f5d66b856959cd
https://doi.org/10.1158/0008-5472.can-22-2525
https://doi.org/10.1158/0008-5472.can-22-2525
Autor:
Jing Huang, Kent W. Hunter, Maxwell Lee, Michael Kruhlak, Aleksandra M. Michalowski, Howard Yang, Laura Vera-Ramirez, Andy D. Tran, Gamze Ayaz, Wendy du Bois, Yu-Chou Tseng, Hualong Yan, Young-Im Kim, Navdeep Malik
This is supplementary Table 4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ddb34c34ca6f21403157cdd129a960
https://doi.org/10.1158/0008-5472.22633260
https://doi.org/10.1158/0008-5472.22633260
Autor:
Jing Huang, Kent W. Hunter, Maxwell Lee, Michael Kruhlak, Aleksandra M. Michalowski, Howard Yang, Laura Vera-Ramirez, Andy D. Tran, Gamze Ayaz, Wendy du Bois, Yu-Chou Tseng, Hualong Yan, Young-Im Kim, Navdeep Malik
This file contains supplementary figure 1-9.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c641bc40c083ae29ab3d13a287ebd48
https://doi.org/10.1158/0008-5472.22633272.v1
https://doi.org/10.1158/0008-5472.22633272.v1
Autor:
Jing Huang, Kent W. Hunter, Maxwell Lee, Michael Kruhlak, Aleksandra M. Michalowski, Howard Yang, Laura Vera-Ramirez, Andy D. Tran, Gamze Ayaz, Wendy du Bois, Yu-Chou Tseng, Hualong Yan, Young-Im Kim, Navdeep Malik
Understanding functional interactions between cancer mutations is an attractive strategy for discovering unappreciated cancer pathways and developing new combination therapies to improve personalized treatment. However, distinguishing driver gene pai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e8ee27498706093ad4460d17b2cfba
https://doi.org/10.1158/0008-5472.c.6599673
https://doi.org/10.1158/0008-5472.c.6599673