Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Maxwell G. Heiman"'
Publikováno v:
Journal of Developmental Biology, Vol 9, Iss 4, p 42 (2021)
The extracellular matrix (ECM) guides and constrains the shape of the nervous system. In C. elegans, DIG-1 is a giant ECM component that is required for fasciculation of sensory dendrites during development and for maintenance of axon positions throu
Externí odkaz:
https://doaj.org/article/d56924a4203d45d3882adb7d6fad2670
Autor:
Zhiqi Candice Yip, Maxwell G. Heiman
Publikováno v:
Cell Reports, Vol 15, Iss 10, Pp 2109-2117 (2016)
Simple cell-cell interactions can give rise to complex cellular patterns. For example, neurons of the same type can interact to create a complex patchwork of non-overlapping dendrite arbors, a pattern known as dendrite tiling. Dendrite tiling often i
Externí odkaz:
https://doaj.org/article/93abdf94ad18427a9f3a4b5112261b7d
Publikováno v:
eLife, Vol 8 (2019)
Coordination of neurite morphogenesis with surrounding tissues is crucial to the establishment of neural circuits, but the underlying cellular and molecular mechanisms remain poorly understood. We show that neurons in a C. elegans sensory organ, call
Externí odkaz:
https://doaj.org/article/c2e0a1714dc04771b7e188a8443b593a
Publikováno v:
bioRxiv
Apical extracellular matrix (aECM) constitutes the interface between every tissue and the outside world. It is patterned into diverse tissue-specific structures through unknown mechanisms. Here, we show that a male-specific genetic switch in a single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb0053adc3aebef6a9f37d35597cd4d
https://doi.org/10.1101/2023.03.17.533199
https://doi.org/10.1101/2023.03.17.533199
Autor:
Zhiqi Candice Yip, Maxwell G Heiman
Publikováno v:
eLife, Vol 7 (2018)
Biological systems are organized into well-ordered structures and can evolve new patterns when perturbed. To identify principles underlying biological order, we turned to C. elegans for its simple anatomy and powerful genetics. We developed a method
Externí odkaz:
https://doaj.org/article/cf22e5812b274a8daa4a3c15c011300a
Publikováno v:
PLoS Genetics, Vol 14, Iss 6, p e1007435 (2018)
Neurons develop elaborate morphologies that provide a model for understanding cellular architecture. By studying C. elegans sensory dendrites, we previously identified genes that act to promote the extension of ciliated sensory dendrites during embry
Externí odkaz:
https://doaj.org/article/82de2ba15e5d4cada11084eed9a44973
Autor:
Maxwell G. Heiman
Publikováno v:
Dev Biol
Neurons and epithelia are viewed as fundamentally different cell types, yet some sensory neurons exhibit hallmarks of epithelial cells. For example, they use tight junctions to form a diffusion barrier continuous with the skin or other epithelia and
Publikováno v:
Genetics. 221
Cells are highly organized machines with functionally specialized compartments. For example, membrane proteins are localized to axons or dendrites in neurons and to apical or basolateral surfaces in epithelial cells. Interestingly, many sensory cells
Publikováno v:
J Neurogenet
Glia shape the development and function of the C. elegans nervous system, especially its sense organs and central neuropil (nerve ring). Cell-type-specific promoters allow investigators to label or manipulate individual glial cell types, and therefor
Publikováno v:
Nature's Gift to Neuroscience ISBN: 9781003239758
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5874cdbbac76ae996b7d53d3e0857f78
https://doi.org/10.1201/9781003239758-15
https://doi.org/10.1201/9781003239758-15