Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Maxwell Ampomah-Wireko"'
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Novel indazole skeleton derivatives containing 1,2,3-triazole as potential anti-prostate cancer drugs
Autor: Yaquan Cao, Yingxue Yang, Maxwell Ampomah-Wireko, Firas Obaid Arhema Frejat, Hongjin Zhai, Shuo Zhang, Huanhuan Wang, Pu Yang, Qingyan Yuan, Guanlian Wu, Chunli Wu
Publikováno v: Bioorganicmedicinal chemistry letters. 64
In this study, a novel batch of indazole containing 1,2,3-triazole agents were designed and synthesized. The antiproliferative activity of target compounds in four human cancer cells, PC-3 (human prostate cancer cell), MCF-7 (human breast cancer cell
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34db25b93e75933da2e335e38d59a628
https://pubmed.ncbi.nlm.nih.gov/35259487
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5
Development of biaromatic core-linked antimicrobial peptide mimics: Substituent position significantly affects antibacterial activity and hemolytic toxicity
Autor: Sen Li, Meng Wang, Shengcong Chen, Maxwell Ampomah-Wireko, Chen Gao, Ziwei Xia, Lauraine Nininahazwe, Shangshang Qin, En Zhang
Publikováno v: European Journal of Medicinal Chemistry. 247:115029
The development of bacterial resistance to the majority of clinically significant antimicrobials has made it more difficult to treat bacterial infections with conventional antibiotics. As part of ongoing research on antimicrobial peptide mimetics, a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7774b4989acb6aceb758a218c3829d
https://doi.org/10.1016/j.ejmech.2022.115029
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6
Epigenetic compounds targeting pharmacological target lysine specific demethylase 1 and its impact on immunotherapy, chemotherapy and radiotherapy for treatment of tumor recurrence and resistance
Autor: Clement Agboyibor, Jianshu Dong, Clement Yaw Effah, Emmanuel Kwateng Drokow, Maxwell Ampomah-Wireko, Waqar Pervaiz, Augustina Sangmor, Xinli Ma, Jian Li, Hong-Min Liu, Peng Zhang
Publikováno v: Biomedicine & Pharmacotherapy. 157:113934
It has been proven that metastatic recurrence and therapeutic resistance are linked. Due to the variability of individuals and tumors, as well as the tumor's versatility in avoiding therapies, therapy resistance is more difficult to treat. Therapy re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a3ecd74a16a74e98303e4ca933ee21
https://doi.org/10.1016/j.biopha.2022.113934
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7
Chemical probe of AHL modulators on quorum sensing in Gram-Negative Bacteria and as antiproliferative agents: A review
Autor: Y H Cao, Chunli Wu, Huanhuan Wang, Chunying Luo, Lauraine Nininahazwe, Maxwell Ampomah-Wireko
Publikováno v: European journal of medicinal chemistry. 226
Pathogenic bacteria use an intercellular chemical communication system called quorum sensing (QS) to control the expression of cellular functions such as virulence factors, biofilm formation, toxin production, and antibiotic resistance in a manner th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35faf717f620204f900900332b06cdd5
https://pubmed.ncbi.nlm.nih.gov/34626877
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8
Isoquinolines: Important Cores in Many Marketed and Clinical Drugs
Autor: Qing Wang, Hui Zhang, Chunying Luo, Huanhuan Wang, Maxwell Ampomah-Wireko, Chunli Wu, Y H Cao
Publikováno v: Anti-cancer agents in medicinal chemistry. 21(7)
Background: Isoquinoline analogs are an important, structurally diverse class of compounds that are extensively used as pharmaceuticals. Derivatives containing the isoquinoline scaffold have become a focus of therapeutic research because of their wid
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62deba1e9e9e84381d70083a86e74eb7
https://pubmed.ncbi.nlm.nih.gov/32329698
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