Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Maxmillian, Mpina"'
Autor:
Robert A. Mitchell, Dídac Macià, Chenjerai Jairoce, Maxmillian Mpina, Akshayata Naidu, Ana Chopo-Pizarro, Miquel Vázquez-Santiago, Joseph J. Campo, Pedro Aide, Ruth Aguilar, Claudia Daubenberger, Carlota Dobaño, Gemma Moncunill
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract RTS,S/AS01E, the first approved malaria vaccine, demonstrated moderate efficacy during the phase 3 pediatric trial. We previously investigated cell-mediated immune (CMI) responses following the primary 3-dose immunization and now report resp
Externí odkaz:
https://doaj.org/article/3a402c91bf4e4e8180927d8ab6d0ff2e
Autor:
Mathilde Foglierini, Pauline Nortier, Rachel Schelling, Rahel R. Winiger, Philippe Jacquet, Sijy O’Dell, Davide Demurtas, Maxmillian Mpina, Omar Lweno, Yannick D. Muller, Constantinos Petrovas, Claudia Daubenberger, Matthieu Perreau, Nicole A. Doria-Rose, Raphael Gottardo, Laurent Perez
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Broadly neutralizing antibodies (bNAbs) are promising candidates for the treatment and prevention of HIV-1 infections. Despite their critical importance, automatic detection of HIV-1 bNAbs from immune repertoires is still lacking. Here, we d
Externí odkaz:
https://doaj.org/article/9d102f79207c417eb04c2d3080c48cb2
Autor:
Maxmillian Mpina, Thomas C. Stabler, Tobias Schindler, Jose Raso, Anna Deal, Ludmila Acuche Pupu, Elizabeth Nyakarungu, Maria del Carmen Ovono Davis, Vicente Urbano, Ali Mtoro, Ali Hamad, Maria Silvia A. Lopez, Beltran Pasialo, Marta Alene Owono Eyang, Matilde Riloha Rivas, Carlos Cortes Falla, Guillermo A. García, Juan Carlos Momo, Raul Chuquiyauri, Elizabeth Saverino, L. W. Preston Church, B. Kim lee Sim, Bonifacio Manguire, Marcel Tanner, Carl Maas, Salim Abdulla, Peter F. Billingsley, Stephen L. Hoffman, Said Jongo, Thomas L. Richie, Claudia A. Daubenberger
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-14 (2022)
Abstract Background Progress towards malaria elimination has stagnated, partly because infections persisting at low parasite densities comprise a large reservoir contributing to ongoing malaria transmission and are difficult to detect. This study com
Externí odkaz:
https://doaj.org/article/afc3035edca147288642779878104b0a
Autor:
Salome Hosch, Charlene Aya Yoboue, Olivier Tresor Donfack, Etienne A. Guirou, Jean-Pierre Dangy, Maxmillian Mpina, Elizabeth Nyakurungu, Koranan Blöchliger, Carlos A. Guerra, Wonder P. Phiri, Mitoha Ondo’o Ayekaba, Guillermo A. García, Marcel Tanner, Claudia Daubenberger, Tobias Schindler
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-12 (2022)
Abstract Background Surveillance programmes often use malaria rapid diagnostic tests (RDTs) to determine the proportion of the population carrying parasites in their peripheral blood to assess the malaria transmission intensity. Despite an increasing
Externí odkaz:
https://doaj.org/article/b50c2080569c47f88fa80bf56cc91fb5
Autor:
Natasha KC, L. W. Preston Church, Pouria Riyahi, Sumana Chakravarty, Robert A. Seder, Judith E. Epstein, Kirsten E. Lyke, Benjamin Mordmüller, Peter G. Kremsner, Mahamadou S. Sissoko, Sara Healy, Patrick E. Duffy, Said A. Jongo, Vicente Urbano Nsue Ndong Nchama, Salim Abdulla, Maxmillian Mpina, Sodiomon B. Sirima, Matthew B. Laurens, Laura C. Steinhardt, Martina Oneko, MingLin Li, Tooba Murshedkar, Peter F. Billingsley, B. Kim Lee Sim, Thomas L. Richie, Stephen L. Hoffman
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundWhile prior research has shown differences in the risk of malaria infection and sickness between males and females, little is known about sex differences in vaccine-induced immunity to malaria. Identifying such differences could elucidate i
Externí odkaz:
https://doaj.org/article/d6334f1741f1482b91e5bb9239e66e76
Autor:
Fergal J. Duffy, Ying Du, Jason Carnes, Judith E. Epstein, Stephen L. Hoffman, Salim Abdulla, Said Jongo, Maxmillian Mpina, Claudia Daubenberger, John D. Aitchison, Ken Stuart
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-13 (2021)
Abstract Background Vaccination with radiation-attenuated Plasmodium falciparum sporozoites is known to induce protective immunity. However, the mechanisms underlying this protection remain unclear. In this work, two recent radiation-attenuated sporo
Externí odkaz:
https://doaj.org/article/cb869f93c4374310b33c25bf3aa76c3e
Autor:
Vicente Urbano Nsue Ndong Nchama, Ali Hamad Said, Ali Mtoro, Gertrudis Owono Bidjimi, Marta Alene Owono, Escolastica Raquel Mansogo Maye, Martin Eka Ondo Mangue, Genaro Nsue Nguema Okomo, Beltran Ekua Ntutumu Pasialo, Dolores Mbang Ondo, Maria-Silvia Angue Lopez, Fortunata Lobede Mochomuemue, Mariano Obiang Obono, Juan Carlos Momo Besaha, Raul Chuquiyauri, Said Abdallah Jongo, Kassim Kamaka, Ummi Abdul Kibondo, Thabit Athuman, Carlos Cortez Falla, Jeremías Nzamio Mba Eyono, Jordan Michael Smith, Guillermo A. García, José Raso, Elizabeth Nyakarungu, Maxmillian Mpina, Tobias Schindler, Claudia Daubenberger, Laurence Lemiale, Peter F. Billingsley, B. Kim Lee Sim, Thomas L. Richie, L. W. Preston Church, Ally Olotu, Marcel Tanner, Stephen L. Hoffman, Salim Abdulla
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-13 (2021)
Abstract Background Extensive malaria control measures have been implemented on Bioko Island, Equatorial Guinea over the past 16 years, reducing parasite prevalence and malaria-related morbidity and mortality, but without achieving elimination. Malar
Externí odkaz:
https://doaj.org/article/3e7774f81b3642fb8979372514e81536
Autor:
Salome Hosch, Maxmillian Mpina, Elizabeth Nyakurungu, Nelson Silochi Borico, Teodora Mikumu Alogo Obama, Maria Carmen Ovona, Philipp Wagner, Sarah E. Rubin, Ulrich Vickos, Diosdado Vicente Nsue Milang, Mitoha Ondo'o Ayekaba, Wonder P. Phiri, Claudia A. Daubenberger, Tobias Schindler
Publikováno v:
Frontiers in Public Health, Vol 9 (2022)
COVID-19 disease caused by SARS-CoV-2 represents an ongoing global public health emergency. Rapid identification of emergence, evolution, and spread of SARS-CoV-2 variants of concern (VOC) would enable timely and tailored responses by public health d
Externí odkaz:
https://doaj.org/article/2a525d17a62240aaa93a9eb1479f1959
Autor:
Gemma Moncunill, Jason Carnes, William Chad Young, Lindsay Carpp, Stephen De Rosa, Joseph J Campo, Augusto Nhabomba, Maxmillian Mpina, Chenjerai Jairoce, Greg Finak, Paige Haas, Carl Muriel, Phu Van, Héctor Sanz, Sheetij Dutta, Benjamin Mordmüller, Selidji T Agnandji, Núria Díez-Padrisa, Nana Aba Williams, John J Aponte, Clarissa Valim, Daniel E Neafsey, Claudia Daubenberger, M Juliana McElrath, Carlota Dobaño, Ken Stuart, Raphael Gottardo
Publikováno v:
eLife, Vol 11 (2022)
Background: In a phase 3 trial in African infants and children, the RTS,S/AS01 vaccine (GSK) showed moderate efficacy against clinical malaria. We sought to further understand RTS,S/AS01-induced immune responses associated with vaccine protection. Me
Externí odkaz:
https://doaj.org/article/37c360e9cf6d4232954aa26b5b65805e
Autor:
Said A. Jongo, Vicente Urbano Nsue Ndong Nchama, L. W. Preston Church, Ally Olotu, Stephen R. Manock, Tobias Schindler, Ali Mtoro, Natasha KC, Orrin Devinsky, Elcin Zan, Ali Hamad, Elizabeth Nyakarungu, Maxmillian Mpina, Anna Deal, José Raso Bijeri, Martin Eka Ondo Mangue, Beltrán Ekua Ntutumu Pasialo, Genaro Nsue Nguema, Matilde Riloha Rivas, Mwajuma Chemba, Kamaka K. Ramadhani, Eric R. James, Thomas C. Stabler, Yonas Abebe, Pouria Riyahi, Elizabeth S. Saverino, Julian Sax, Salome Hosch, Anneth Tumbo, Linda Gondwe, J. Luis Segura, Carlos Cortes Falla, Wonder Philip Phiri, Dianna E. B. Hergott, Guillermo A. García, Carl Maas, Tooba Murshedkar, Peter F. Billingsley, Marcel Tanner, Mitoha Ondo’o Ayekaba, B. Kim Lee Sim, Claudia Daubenberger, Thomas L. Richie, Salim Abdulla, Stephen L. Hoffman
Publikováno v:
The American Journal of Tropical Medicine and Hygiene.
The radiation-attenuated Plasmodium falciparum sporozoites (PfSPZ) Vaccine has demonstrated safety and immunogenicity in 5-month-old to 50-year-old Africans in multiple trials. Except for one, each trial has restricted enrollment to either infants an