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Significant improvement of psychotic symptoms in treatment-resistant schizophrenia with clozapine in an adolescent with SHINE syndrome: a case report

Autor: Maxine Yang, Arielle Rubin, Rebecca Wondimu, Theresa Grebe, Gaby Ritfeld

Publikováno v: BMC Psychiatry, Vol 23, Iss 1, Pp 1-5 (2023)

Abstract This report highlights a rare single-gene cause of early-onset, treatment-resistant schizophrenia, and its unique responsiveness to clozapine therapy. This case describes a pediatric female who was diagnosed with early-onset schizophrenia an

Externí odkaz: https://doaj.org/article/5c6c61d216334e20bbcf7828526a3a95

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Empty class II major histocompatibility complex created by peptide photolysis establishes the role of DM in peptide association

Autor: Maxine Yang, Arup K. Chakraborty, Kai W. Wucherpfennig, Kathrin Wilbuer, Gijsbert M. Grotenbreg, Melissa J. Nicholson, Leah M. Octavio, Kevin D. Fowler, Hidde L. Ploegh

Publikováno v: The Journal of biological chemistry. 282(29)

DM catalyzes the exchange of peptides bound to Class II major histocompatibility complex (MHC) molecules. Because the dissociation and association components of the overall reaction are difficult to separate, a detailed mechanism of DM catalysis has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc48a0b5c041cb7e8fdb633dd1d620d
https://pubmed.ncbi.nlm.nih.gov/17525157

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