Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Maxine L. Crook"'
Autor:
Maxine L. Crook, Colin J.R. Stewart
Publikováno v:
International Journal of Gynecological Pathology. 35:566-573
The transcription factor SOX2 plays an important role in tissue development and differentiation. In the neoplastic context, SOX2 has been shown to potentiate tumor invasion, and increased SOX2 immunoreactivity has been demonstrated in a variety of ep
Autor:
Sukeerat Ruba, Colin J.R. Stewart, Yancey Wilson, Chrianna Bharat, Ai Rene Kee, Maxine L. Crook, Joanne Peverall
Publikováno v:
Pathology. 48:550-554
The distinction between partial hydatidiform mole (PHM) and trisomy gestation is not always straightforward histologically and it is unclear which morphological features, alone or in combination, provide the greatest diagnostic accuracy. We performed
Publikováno v:
Pathology. 47:112-117
It has been proposed recently that stromal cell p16 immunoreactivity may be useful in the diagnosis of endometrial polyps (EPs). However, the specificity of p16 staining is uncertain and it is also unclear whether sporadic and tamoxifen-related polyp
Autor:
Maxine L. Crook, Colin J.R. Stewart
Publikováno v:
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 37(1)
Squamous cell carcinoma (SCC) of the uterine cervix occasionally demonstrates a deceptive growth pattern that mimics endocervical crypt involvement by cervical intraepithelial neoplasia, grade 3 (CIN 3). Such CIN 3-like SCCs may be misinterpreted as
Publikováno v:
Histopathology. 65:363-370
Aims Extravascular migratory metastasis (EVMM) is a potential mechanism of tumour spread reported most extensively in cutaneous melanoma. It has not been described previously in gynaecological malignancies. We describe EVMM in four gynaecological car
Publikováno v:
Human Pathology. 44:2774-2781
Most ovarian sex cord-stromal tumors (SCSTs) can be categorized on the basis of conventional histology, but approximately 10% of cases are unclassified because they present indeterminate or overlapping morphologic features. Immunohistochemical and mo
Autor:
Maxine L. Crook, Colin J.R. Stewart
Publikováno v:
Journal of Clinical Pathology. 67:319-325
Aims To investigate cyclin D1 and fascin immunoreactivity in normal, reactive and neoplastic vulvar skin correlating the findings with p16 protein and Ki67 expression. Methods 66 vulvar biopsy or resection specimens demonstrating normal appearances,
Publikováno v:
Pathology. 45:559-566
Summary Aims The relationship between endometriosis and ovarian endometrioid adenocarcinoma (OEC) is well recognised but it is unclear whether endometriosis positive and negative OECs develop via similar pathogenetic mechanisms. Materials Sixty-seven
Autor:
Colin J.R. Stewart, Maxine L. Crook
Publikováno v:
Histopathology. 70(3)
Aims To review the clinicopathological features of 14 cases of CIN 3-like squamous cell carcinoma (SCC) of the cervix and to investigate possible mechanisms of tumour invasion in the CIN 3-like and ‘conventional’ (infiltrative) tumour components.
Publikováno v:
Pathology. 48(5)
The aim of this study was to perform an immunohistochemical comparison of uterine tumour resembling ovarian sex cord-stromal tumour (UTROSCT) and other uterine lesions with sex cord-like (SCL) differentiation. Six UTROSCTs and 10 potential histologic