Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Maxine J. Allen"'
Autor:
Sabine Kupzig, Takashi Tsuboi, Trever G. Bivona, Peter J. Lockyer, Louise C Davies, Maxine J. Allen, Gyles E. Cozier, Guy A. Rutter, Peter J. Cullen, Simon Walker, Alan Buckler, Dalila Bouyoucef, Mark R. Philips
Publikováno v:
The EMBO Journal. 23:1749-1760
Receptor-mediated increases in the concentration of intracellular free calcium ([Ca2+]i) are responsible for controlling a plethora of physiological processes including gene expression, secretion, contraction, proliferation, neural signalling, and le
Publikováno v:
Gene. 218:17-25
The mammalian rasGAPs constitute a group of widely expressed proteins involved in the negative regulation of ras-mediated signaling. In this study we have isolated a novel human gene, RASAL (Ras GTPase-activating-like) and its murine ortholog, MRASAL
Publikováno v:
Genome Research. 4:71-75
Vectorette PCR permits the specific amplification of DNA segments flanking a known DNA sequence. It enables the application of the PCR where sequence information is only available for one primer site. We now show that vectorette PCR can be used for t
Autor:
Sheila C. Barton, Andrew Collick, M. A. Surani, Alec J. Jeffreys, Michael L. Norris, Maxine J. Allen
Publikováno v:
Nucleic Acids Research. 22:2976-2981
The human hypervariable minisatellite MS32 has a well characterised internal repeat unit array and high mutation rates have been observed at this locus. Analysis of MS32 mutants has shown that male germline mutations are polarised to one end of the a
Publikováno v:
Forensic Science International. 56:65-76
There has been considerable controversy over the identity of the skeletal remains exhumed in Brazil in 1985 and believed to be those of Dr Josef Mengele, the Auschwitz 'Angel of Death'. Bone DNA analysis was therefore conducted in an attempt to provi
Autor:
Maxine J. Allen, Annette MacLeod, Darren G. Monckton, Alec J. Jeffreys, Keiji Tamaki, David L. Neil
Publikováno v:
Human Molecular Genetics. 1:401-406
Minisatellite variant repeat mapping by PCR (MVR-PCR) is a new approach to studying variation in human DNA which analyses interspersion patterns of variant repeats within minisatellite arrays. MVR-PCR has been applied to the hypervariable human minis
Publikováno v:
Immunogenetics. 51(10)
Autor:
Mark A. Jobling, Neale Fretwell, Tara Guram, Yuri E. Dubrova, Rita Neumann, Andrew Collick, David L. Neil, Maxine J. Allen, Alec J. Jeffreys, Celia A. May, John A.L. Armour
Publikováno v:
Electrophoresis. 16(9)
Minisatellites provide one of the most experimentally tractable systems for studying tandem repeat instability in man. Analysis of mutation processes has been greatly aided by the development of single molecule methods for recovering de novo mutants,
Autor:
Maxine J. Allen, Alec J. Jeffreys, S.C. Barton, M. A. Surani, Philippe Bois, M.L. Norris, Andrew Collick
Publikováno v:
Scopus-Elsevier
Tandem repeat loci such as minisatellites and trinucleotide repeats frequently show instability. We have investigated mutation at human minisatellite MS32 (locus D1S8) transferred to transgenic mice. Three lines of hemizygous transgenic mice were stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7038ee4fb464a245f57d10f6f2b278
https://europepmc.org/articles/PMC395540/
https://europepmc.org/articles/PMC395540/
Publikováno v:
Human molecular genetics. 2(10)
Minisatellite variant repeat mapping by PCR (MVR-PCR) provides a digital approach to DNA typing that can reveal huge levels of variation at minisatellite loci. MVR-PCR has so far been applied to three human minisatellites, including the hypervariable