Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Maxine Holder"'
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234744 (2020)
Developmental processes require strict regulation of proliferation, differentiation and patterning for the generation of final organ size. Aberrations in these fundamental events are critically important in tumorigenesis and cancer progression. Salt
Externí odkaz:
https://doaj.org/article/f6e6c13fb20d430db3eaa78240913ddf
Autor:
Yavuz Kulaberoglu, Kui Lin, Maxine Holder, Zhongchao Gai, Marta Gomez, Belul Assefa Shifa, Merdiye Mavis, Lily Hoa, Ahmad A. D. Sharif, Celia Lujan, Ewan St. John Smith, Ivana Bjedov, Nicolas Tapon, Geng Wu, Alexander Hergovich
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
The Hippo tumor suppressor pathway is essential for development and tissue growth control. Here the authors employ a multi-disciplinary approach to characterize the interactions of the three Hippo kinases with the signaling adaptor MOB1 and show how
Externí odkaz:
https://doaj.org/article/057c5004ddb54609858a2e780a18b291
Autor:
Despina Stamataki, Maxine Holder, Christine Hodgetts, Rosemary Jeffery, Emma Nye, Bradley Spencer-Dene, Douglas J Winton, Julian Lewis
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24484 (2011)
The stem cells of the small intestine are multipotent: they give rise, via transit-amplifying cell divisions, to large numbers of columnar absorptive cells mixed with much smaller numbers of three different classes of secretory cells--mucus-secreting
Externí odkaz:
https://doaj.org/article/74e36a9ee792498fb303407fd1ed16cc
Autor:
Georgina C, Fletcher, Maria-Del-Carmen, Diaz-de-la-Loza, Nerea, Borreguero-Muñoz, Maxine, Holder, Mario, Aguilar-Aragon, Barry J, Thompson
Publikováno v:
Development (Cambridge, England)
Animal cells are thought to sense mechanical forces via the transcriptional co-activators YAP (or YAP1) and TAZ (or WWTR1), the sole Drosophila homolog of which is named Yorkie (Yki). In mammalian cells in culture, artificial mechanical forces induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58545ebade72ca237ea416b7d1b63881
https://pubmed.ncbi.nlm.nih.gov/29440303
https://pubmed.ncbi.nlm.nih.gov/29440303