Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Maxine, Bauzon"'
Autor:
Xiao-Yan Zhao, Andreas Wilmen, Dongli Wang, Xinquan Wang, Maxine Bauzon, Ji-Yun Kim, Lars Linden, Liang Li, Ursula Egner, Tobias Marquardt, Dieter Moosmayer, Jan Tebbe, Julian Marius Glück, Philipp Ellinger, Kirk McLean, Shujun Yuan, Subramanian Yegneswaran, Xiaoqiao Jiang, Vince Evans, Jian-Ming Gu, Doug Schneider, Ying Zhu, Yifan Xu, Cornell Mallari, Ashley Hesslein, Yan Wang, Nicole Schmidt, Katrin Gutberlet, Christine Ruehl-Fehlert, Alexius Freyberger, Terry Hermiston, Chandra Patel, Derek Sim, Laurent O. Mosnier, Volker Laux
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Activated protein C (APC) is a plasma serine protease with antithrombotic and cytoprotective functions. Here, the authors develop a monoclonal antibody that specifically inhibits APC’s anticoagulant function without compromising its cytoprotective
Externí odkaz:
https://doaj.org/article/9ba7c3d64bcb4b03984dbf3b38cd94db
Autor:
Gloria I. Perez, Matthew P. Bernard, Daniel Vocelle, Ahmed A. Zarea, Najla A. Saleh, Matthew A. Gagea, Doug Schneider, Maxine Bauzon, Terry Hermiston, Masamitsu Kanada
Publikováno v:
Vaccines, Vol 11, Iss 3, p 639 (2023)
Under physiological conditions, phosphatidylserine (PS) predominantly localizes to the cytosolic leaflet of the plasma membrane of cells. During apoptosis, PS is exposed on the cell surface and serves as an “eat-me” signal for macrophages to prev
Externí odkaz:
https://doaj.org/article/50bc23899f44422ba004514967868104
Autor:
Derek S. Sim, Cornell R. Mallari, John M. Teare, Richard I. Feldman, Maxine Bauzon, Terry W. Hermiston
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 5, Pp n/a-n/a (2021)
Abstract Background Traumatic injury and the associated acute bleeding are leading causes of death in people aged 1 to 44 years. Acute bleeding in pathological and surgical settings also represents a significant burden to the society. Yet there are n
Externí odkaz:
https://doaj.org/article/14a0e9c3e7554a8ebeb2a6299ca954bd
Preclinical Safety Studies of Enadenotucirev, a Chimeric Group B Human-Specific Oncolytic Adenovirus
Autor:
Sam Illingworth, Ying Di, Maxine Bauzon, Janet Lei, Margaret R. Duffy, Simon Alvis, Brian Champion, André Lieber, Terry Hermiston, Len W. Seymour, John Beadle, Kerry Fisher
Publikováno v:
Molecular Therapy: Oncolytics, Vol 5, Iss C, Pp 62-74 (2017)
Enadenotucirev is an oncolytic group B adenovirus identified by a process of bio-selection for the ability to selectively propagate in and rapidly kill carcinoma cells. It is resistant to inactivation by human blood components, potentially enabling i
Externí odkaz:
https://doaj.org/article/a7c13d435d3b499f8c2068ee8f9375b9
Publikováno v:
Molecular Therapy: Oncolytics, Vol 4, Iss C, Pp 55-66 (2017)
Effective therapeutics for ovarian cancer continue to be urgently needed, particularly for chemotherapy-resistant cases. Here we present both a 3D-Matrigel culture-based expansion of our directed evolution method for generation of oncolytic virothera
Externí odkaz:
https://doaj.org/article/6d5b190ffaa8499498f0c556914be3db
Autor:
Maxine Bauzon, Penelope M. Drake, Robyn M. Barfield, Brandon M. Cornali, Igor Rupniewski, David Rabuka
Publikováno v:
OncoImmunology, Vol 8, Iss 4 (2019)
Oncology treatment has been revolutionized by the introduction of immune checkpoint inhibitor drugs, which enable 20–40% of patients to generate anti-tumor immune responses. Combination treatment approaches with chemotherapeutic drugs may enable re
Externí odkaz:
https://doaj.org/article/485d4ac33e984703b5b4c626ef35afe2
Autor:
Penelope M. Drake, David Rabuka, Mark D. Pegram, Colin Hickle, Dominick Yeo, Ayodele O. Ogunkoya, Maxine Bauzon, Fangjiu Zhang, Stepan Chuprakov, Yun Cheol Kim, Robyn M. Barfield
Contains 3 tables and 8 figures with legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b90b891f0338273763849f4ed50af1
https://doi.org/10.1158/1535-7163.22521129
https://doi.org/10.1158/1535-7163.22521129
Autor:
Derek S Sim, Meenal Shukla, Cornell R Mallari, José A. Fernández, Xiao Xu, Doug Schneider, Maxine Bauzon, Terry W Hermiston, Laurent O. Mosnier
Publikováno v:
Blood Advances.
Activated protein C (APC) is a pleiotropic coagulation protease with anticoagulant, anti-inflammatory, and cytoprotective activities. Selective modulation of these APC activities contributes to our understanding of the regulation of these physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e216e9bfd3fd7050dbf277811243739b
https://doi.org/10.1182/bloodadvances.2022008740
https://doi.org/10.1182/bloodadvances.2022008740
Autor:
Gloria I. Perez, Matthew P. Bernard, Daniel Vocelle, Ahmed A. Zarea, Doug Schneider, Maxine Bauzon, Terry Hermiston, Masamitsu Kanada
Under physiological conditions, phosphatidylserine (PS) predominantly localizes to the cytosolic leaflet of the plasma membrane of cells. During apoptosis, PS is exposed on the cell surface and serves as an “eat-me” signal for macrophages to prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::357b2770d5fb36dba8ae9cbd3902ab8d
https://doi.org/10.1101/2022.11.17.516966
https://doi.org/10.1101/2022.11.17.516966
Autor:
Fangjiu Zhang, Ayodele O. Ogunkoya, David Rabuka, Penelope M. Drake, Colin Hickle, Maxine Bauzon, Yun Cheol Kim, Dominick Yeo, Robyn M. Barfield, Stepan Chuprakov
Publikováno v:
Bioconjugate Chemistry. 32:746-754
Although peptide motifs represent the majority of cleavable linkers used in clinical-stage antibody-drug conjugates (ADCs), the sequences are often sensitive to cleavage by extracellular enzymes, such as elastase, leading to systemic release of the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40dc867df1e6c62ea7d5dd6162086eff
https://doi.org/10.1021/acs.bioconjchem.1c00029
https://doi.org/10.1021/acs.bioconjchem.1c00029