Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Maximillian A. Robinson"'
Autor:
Maximillian A. Robinson, Alan Kennedy, Carolina T. Orozco, Hung-Chang Chen, Erin Waters, Dalisay Giovacchini, Kay Yeung, Lily Filer, Claudia Hinze, Christopher Lloyd, Simon J. Dovedi, David M. Sansom
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114768- (2024)
Summary: The CTLA-4 and PD-1 checkpoints control immune responses and are key targets in immunotherapy. Both pathways are connected via a cis interaction between CD80 and PD-L1, the ligands for CTLA-4 and PD-1, respectively. This cis interaction prev
Externí odkaz:
https://doaj.org/article/bd659b5fd6cd460e8b103ac0c7d928f7
Autor:
Cayman Williams, Alan Kennedy, Maximillian A. Robinson, Christopher Lloyd, Simon J. Dovedi, David M. Sansom
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Anti-CTLA-4 antibodies have pioneered the field of tumour immunotherapy. However, despite impressive clinical response data, the mechanism by which anti-CTLA-4 antibodies work is still controversial. Two major checkpoint antibodies (ipilimumab and tr
Externí odkaz:
https://doaj.org/article/50e5c69156f645a59e40cf30cc612fe5
Autor:
Alan Kennedy, Maximillian A Robinson, Claudia Hinze, Erin Waters, Cayman Williams, Neil Halliday, Simon Dovedi, David M Sansom
Publikováno v:
The EMBO Journal. 42