Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Maximilien Vanleene"'
Autor:
Gemma N Jones, Dafni Moschidou, Tamara-Isabel Puga-Iglesias, Katarzyna Kuleszewicz, Maximilien Vanleene, Sandra J Shefelbine, George Bou-Gharios, Nicholas M Fisk, Anna L David, Paolo De Coppi, Pascale V Guillot
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43395 (2012)
Human mesenchymal stromal/stem cells (MSC) isolated from fetal tissues hold promise for use in tissue engineering applications and cell-based therapies, but their collection is restricted ethically and technically. In contrast, the placenta is a pote
Externí odkaz:
https://doaj.org/article/9daf098975aa48ffa18a8f9bc460f3f2
Publikováno v:
Bone
Osteogenesis imperfecta (OI) is characterized by extremely brittle bone. Currently, bisphosphonate drugs allow a decrease of fracture by inhibiting bone resorption and increasing bone mass but with possible long term side effects. Whole body mechanic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee9c2664d9a06d112611103ab39a4b0
https://doi.org/10.1016/j.bone.2013.01.023
https://doi.org/10.1016/j.bone.2013.01.023
Autor:
Anna M. Ranzoni, Michelangelo Corcelli, Kwan-Leong Hau, Jemma G. Kerns, Maximilien Vanleene, Sandra Shefelbine, Gemma N. Jones, Dafni Moschidou, Benan Dala-Ali, Allen E. Goodship, Paolo De Coppi, Timothy R. Arnett, Pascale V. Guillot
Publikováno v:
Scientific Reports.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=issn20452322::20de2ebf63ddab61fb772166f2604a02
Autor:
Hassan Abdulrazzak, Dafni Moschidou, Suchaya Osatis, Sandra J. Shefelbine, Pascale V. Guillot, Nicole J. Horwood, J. H. Duncan Bassett, Bhalraj Singh Kalirai, Gemma N. Jones, Graham R. Williams, Massimo Marenzana, Maximilien Vanleene, Nicholas M. Fisk, Paolo De Coppi
Osteogenesis imperfecta (OI) is a genetic bone pathology with prenatal onset, characterized by brittle bones in response to abnormal collagen composition. There is presently no cure for OI. We previously showed that human first trimester fetal blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d3b04931aac4974a42cb3c5f8645da
https://ora.ox.ac.uk/objects/uuid:3293800c-2cc4-4fe5-bd05-55ae652967c2
https://ora.ox.ac.uk/objects/uuid:3293800c-2cc4-4fe5-bd05-55ae652967c2
Autor:
Nicholas M. Fisk, Sandra J. Shefelbine, Dafni Moschidou, Paolo De Coppi, Hassan Abdulrazzak, Gemma N. Jones, Kenneth Lay, Pascale V. Guillot, Maximilien Vanleene, Julia M. Polak
Publikováno v:
Stem Cells Translational Medicine. 1:70-78
Stem cells have considerable potential to repair damaged organs and tissues. We previously showed that prenatal transplantation of human first trimester fetal blood mesenchymal stem cells (hfMSCs) in a mouse model of osteogenesis imperfecta (oim mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b592a666c177fa0e5a3e45910ddb89e1
https://doi.org/10.5966/sctm.2011-0007
https://doi.org/10.5966/sctm.2011-0007
Autor:
Robin Olsson, Sandra J. Shefelbine, Andrew A. Pitsillides, Rebecca Collinson, Pavel Sztefek, Maximilien Vanleene
Publikováno v:
Journal of Biomechanics. 43:599-605
Previous models of cortical bone adaptation, in which loading is imposed on the bone, have estimated the strains in the tissue using strain gauges, analytical beam theory, or finite element analysis. We used digital image correlation (DIC), tracing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05699b69bd23cb8b4df2bb6aa3c5c133
https://doi.org/10.1016/j.jbiomech.2009.10.042
https://doi.org/10.1016/j.jbiomech.2009.10.042
Publikováno v:
Journal of Materials Research. 21:2093-2097
Investigations of bone mechanical properties are of major importance for bone pathology research, biomaterials, and development of in vivo bone characterization devices. Because of its complex multiscale structure, assessment of bone microstructure i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77f88d7932033f0ec9c5023f2ea5ee97
https://doi.org/10.1557/jmr.2006.0255
https://doi.org/10.1557/jmr.2006.0255
Autor:
Maximilien Vanleene, Gavin Jell, George Bou-Gharios, Kristy L. Cloyd, Zahraa Saldanha, Sandra J. Shefelbine, J. H. Duncan Bassett, Graham R. Williams, Pascale V. Guillot, Molly M. Stevens, Michelle L. Oyen, Nicholas M. Fisk
Publikováno v:
Blood. 117(3)
Osteogenesis imperfecta (OI or brittle bone disease) is a disorder of connective tissues caused by mutations in the collagen genes. We previously showed that intrauterine transplantation of human blood fetal stem/stromal cells in OI mice (oim) result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f183c51597ac56819cd9c9983242a1
http://ora.ox.ac.uk/objects/uuid:3910dd22-aa93-411b-a6c5-afb0cc27bacb
http://ora.ox.ac.uk/objects/uuid:3910dd22-aa93-411b-a6c5-afb0cc27bacb
Autor:
Sandra J. Shefelbine, Donna E. Davies, Maximilien Vanleene, Peter H. Howarth, Philipp J. Thurner, Markus J. Buehler, Shu-Wei Chang, Orestis G. Andriotis
Publikováno v:
Journal of the Royal Society Interface
The Royal Society
The Royal Society
The collagen molecule, which is the building block of collagen fibrils, is a triple helix of two α1(I) chains and one α2(I) chain. However, in the severe mouse model of osteogenesis imperfecta (OIM), deletion of the COL1A2 gene results in the subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739f34eefcbe6ef162fe379bcf59d63d
https://doi.org/10.1098/rsif.2015.0701
https://doi.org/10.1098/rsif.2015.0701
Autor:
Paolo De Coppi, Tamara-Isabel Puga-Iglesias, George Bou-Gharios, Anna L. David, Pascale V. Guillot, Katarzyna Kuleszewicz, Nicholas M. Fisk, Maximilien Vanleene, Dafni Moschidou, Gemma N. Jones, Sandra J. Shefelbine
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43395 (2012)
PLoS ONE
PLoS ONE
Human mesenchymal stromal/stem cells (MSC) isolated from fetal tissues hold promise for use in tissue engineering applications and cell-based therapies, but their collection is restricted ethically and technically. In contrast, the placenta is a pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad47b2aa9609fcc6ed0c071a452f5f6
https://doi.org/10.1371/journal.pone.0043395
https://doi.org/10.1371/journal.pone.0043395