Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Maximilian Zwiebel"'
Autor:
Giorgia Massacci, Veronica Venafra, Maximilian Zwiebel, Maria Wahle, Rocco Cerroni, Jacopo Bissacco, Livia Perfetto, Vito Michienzi, Alessandro Stefani, Nicola Biagio Mercuri, Tommaso Schirinzi, Francesca Sacco
Publikováno v:
Neurobiology of Disease, Vol 200, Iss , Pp 106622- (2024)
The complexity and heterogeneity of PD necessitate advanced diagnostic and prognostic tools to elucidate its molecular mechanisms accurately. In this study, we addressed this challenge by conducting a pilot phospho-proteomic analysis of peripheral bl
Externí odkaz:
https://doaj.org/article/950cc03d9ec44c17b6dac7150ecc5c5c
Autor:
Marta Murgia, Lorenza Brocca, Elena Monti, Martino V. Franchi, Maximilian Zwiebel, Sophia Steigerwald, Emiliana Giacomello, Roberta Sartori, Sandra Zampieri, Giovanni Capovilla, Mladen Gasparini, Gianni Biolo, Marco Sandri, Matthias Mann, Marco V. Narici
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 439-451 (2023)
Abstract Background Inactivity and unloading induce skeletal muscle atrophy, loss of strength and detrimental metabolic effects. Bed rest is a model to study the impact of inactivity on the musculoskeletal system. It not only provides information for
Externí odkaz:
https://doaj.org/article/9d9b8bbf22f641feb6b345de3ca07c32
Autor:
Lisa Schweizer, Tina Schaller, Maximilian Zwiebel, Özge Karayel, Johannes Bruno Müller‐Reif, Wen‐Feng Zeng, Sebastian Dintner, Thierry M Nordmann, Klaus Hirschbühl, Bruno Märkl, Rainer Claus, Matthias Mann
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 9, Pp n/a-n/a (2023)
Abstract SARS‐CoV‐2 may directly and indirectly damage lung tissue and other host organs, but there are few system‐wide, untargeted studies of these effects on the human body. Here, we developed a parallelized mass spectrometry (MS) proteomics
Externí odkaz:
https://doaj.org/article/901eda2487d34885bb7571aa2ad46f4e
Autor:
Manuela Thienel, Johannes B. Müller-Reif, Zhe Zhang, Vincent Ehreiser, Judith Huth, Khrystyna Shchurovska, Badr Kilani, Lisa Schweizer, Philipp E. Geyer, Maximilian Zwiebel, Julia Novotny, Enzo Lüsebrink, Gemma Little, Martin Orban, Leo Nicolai, Shaza El Nemr, Anna Titova, Michael Spannagl, Jonas Kindberg, Alina L. Evans, Orpheus Mach, Matthias Vogel, Steffen Tiedt, Steffen Ormanns, Barbara Kessler, Anne Dueck, Andrea Friebe, Peter Godsk Jørgensen, Monir Majzoub-Altweck, Andreas Blutke, Amin Polzin, Konstantin Stark, Stefan Kääb, Doris Maier, Jonathan M. Gibbins, Ulrich Limper, Ole Frobert, Matthias Mann, Steffen Massberg, Tobias Petzold
Publikováno v:
Science. 380:178-187
Venous thromboembolism (VTE) comprising deep venous thrombosis and pulmonary embolism is a major cause of morbidity and mortality. Short-term immobility-related conditions are a major risk factor for the development of VTE. Paradoxically, long-term i
Autor:
Lisa Schweizer, Tina Schaller, Maximilian Zwiebel, Özge Karayel, Johannes B. Müller-Reif, Wen-Feng Zeng, Sebastian Dintner, Klaus Hirschbühl, Bruno Märkl, Rainer Claus, Matthias Mann
SARS-CoV-2 directly damages lung tissue via its infection and replication process and indirectly due to systemic effects of the host immune system. There are few systems-wide, untargeted studies of these effects on the different tissues of the human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f521c00e6a8bdafb09ce7e8a3c60eb4d
https://doi.org/10.1101/2022.12.21.22283785
https://doi.org/10.1101/2022.12.21.22283785
Autor:
Alexander Dietrich, Monica Steffi Matchado, Maximilian Zwiebel, Benjamin Ölke, Michael Lauber, Ilias Lagkouvardos, Jan Baumbach, Dirk Haller, Beate Brandl, Thomas Skurk, Hans Hauner, Sandra Reitmeier, Markus List
Publikováno v:
Microbial Genomics. 8
16S rRNA gene profiling is currently the most widely used technique in microbiome research and allows for studying microbial diversity, taxonomic profiling, phylogenetics, functional and network analysis. While a plethora of tools have been developed
Autor:
Maximilian T. Strauss, Isabell Bludau, Andreas-David Brunner, Florian Meier, Matthias Mann, André C. Michaelis, Maximilian Zwiebel
Nearly all cellular functions are mediated by protein-protein interactions and mapping the interactome provides fundamental insights into the regulation and structure of biological systems. In principle, affinity purification coupled to mass spectrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::774dbfd4b4db4e689ebc53d855bad5fc
https://doi.org/10.1101/2021.10.24.465633
https://doi.org/10.1101/2021.10.24.465633
Autor:
Thomas Engleitner, Maximilian Zwiebel, Ignacio Varela, Günter Schneider, Sebastian Mueller, Sebastian Lange, Fengtang Yang, Roman Maresch, Mathias J Friedrich, Ruby Banerjee, Dieter Saur, Roland Rad, George S. Vassiliou, Laura González-Silva
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nat Protoc . 2020 Feb;15(2):266-315.
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Nature Protocols
instname
Nat Protoc . 2020 Feb;15(2):266-315.
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Nature Protocols
Mouse models of human cancer have transformed our ability to link genetics, molecular mechanisms and phenotypes. Both reverse and forward genetics in mice are currently gaining momentum through advances in next-generation sequencing (NGS). Methodolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948776edcbddb33caf4424aa021b7859
http://hdl.handle.net/10261/223207
http://hdl.handle.net/10261/223207
Autor:
Beiyuan Fu, Dieter Saur, Christian Veltkamp, Thomas Engleitner, Alex Strong, Wolfgang Enard, Sebastian Mueller, Sebastian Lange, Magdalena Zukowska, Nina Schönhuber, Thorsten Kaltenbacher, Mathias J Friedrich, Ruby Banerjee, Maxim Barenboim, Hsi-Yu Yen, Julia Hess, Pentao Liu, Barbara Seidler, Swati Parekh, Björn Konukiewitz, Sabine Klein, Maximilian Zwiebel, Jorge de la Rosa, Lena Rad, Roman Maresch, Stefan Eser, Allan Bradley, Kathleen Schuck, Fernando Constantino-Casas, Roland Rad, Juliana Götzfried, Sandra Louzada, Fengtang Yang, Günter Klöppel, Christoph Ziegenhain, Mario F. Fraga, Marta I. Sierra, Ignacio Varela, Juan Cadiñanos, Rupert Öllinger, Wilko Weichert, Zonera Hassan, Katja Steiger, Günter Schneider, Oliver M. Dovey, Julia Mayerle, Kristian Unger, George S. Vassiliou, Andreas Arbeiter, Roland M. Schmid
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature 554, 62-68 (2018)
Nature
instname
Nature 554, 62-68 (2018)
Nature
The poor correlation of mutational landscapes with phenotypes limits our understanding of the pathogenesis and metastasis of pancreatic ductal adenocarcinoma (PDAC). Here we show that oncogenic dosage-variation has a critical role in PDAC biology and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e231b6da1f1430a840ea2a8fe3e3f859
http://hdl.handle.net/10261/173621
http://hdl.handle.net/10261/173621
Autor:
Jorge de la Rosa, Magdalena Zukowska, Nina Schönhuber, Thomas Engleitner, Wolfgang Enard, Dieter Saur, Günter Klöppel, Sandra Louzada, Fernando Constantino-Casas, Christian Veltkamp, Sebastian Lange, Marta I. Sierra, Roman Maresch, Alex Strong, Zonera Hassan, Katja Steiger, Barbara Seidler, Sebastian Mueller, Beiyuan Fu, Ignacio Varela, Pentao Liu, Günter Schneider, Stefan Eser, Christoph Ziegenhain, Kathleen Schuck, George S. Vassiliou, Mario F. Fraga, Oliver M. Dovey, Thorsten Kaltenbacher, Juliana Götzfried, Juan Cadiñanos, Julia Hess, Maximilian Zwiebel, Rupert Öllinger, Lena Rad, Allan Bradley, Wilko Weichert, Maxim Barenboim, Swati Parekh, Roland M. Schmid, Kristian Unger, Julia Mayerle, Sabine Klein, Hsi-Yu Yen, Roland Rad, Fengtang Yang, Mathias J Friedrich, Ruby Banerjee, Björn Konukiewitz
Publikováno v:
Cancer Research. 78:391-391
Pancreatic ductal adenocarcinoma (PDAC) has frequent alterations in few genes (KRAS, CDKN2A/TP53/SMAD4) and extensive heterogeneity of cancer drivers beyond. The expectation that mutational landscapes of rare drivers could explain phenotypic diversit