Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Maximilian Woisetschläger"'
Autor:
Cristina Benito‐Villalvilla, Andrés de la Rocha‐Muñoz, Jacobo López‐Abente, Alexander Eggel, Iván Bottoli, Thomas Severin, Maximilian Woisetschläger, Oscar Palomares
Background Ligelizumab is an anti-IgE monoclonal antibody binding IgE with higher affinity than omalizumab that is under clinical investigation for several IgE-mediated diseases. We previously showed that omalizumab removes IgE bound to FcεRI on pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71836badbf1626bec99e45f97240959b
https://eprints.ucm.es/id/eprint/75657/
https://eprints.ucm.es/id/eprint/75657/
Autor:
Maximilian Woisetschläger, Jan Walther Perthold, Haijun Sun, Florian Rüker, Katharina Stadlbauer, Gerhard Stadlmayr, Gordana Wozniak-Knopp
Publikováno v:
Protein engineering, designselection : PEDS. 30(9)
Fc fragment with antigen-binding (Fcab) is a novel construct which can be selected to recognize specifically a wide variety of target proteins. We describe the selection and affinity maturation of Fcab clones targeting VEGF, an important pro-angiogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b81ce74437def8d80695a2b75e55a1
https://pubmed.ncbi.nlm.nih.gov/28981753
https://pubmed.ncbi.nlm.nih.gov/28981753
Autor:
Darina Waltenberger, Maximilian Woisetschläger, Doris Kneidinger, Barbara Platzer, Susanne Richter, Herbert Strobl
Publikováno v:
The Journal of Immunology. 183:66-74
The transcription factor aryl hydrocarbon receptor (AhR) represents a promising therapeutic target in allergy and autoimmunity. AhR signaling induced by the newly described ligand VAF347 inhibits allergic lung inflammation as well as suppresses pancr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5eee45c29ab89c222055aa6b391f6b
https://doi.org/10.4049/jimmunol.0802997
https://doi.org/10.4049/jimmunol.0802997
Autor:
Maximilian Woisetschläger, Barbara Migliavacca, Maria Grazia Roncarolo, Elena Draghici, Silvia Gregori, Stefano Olivieri, Ehud Hauben
Publikováno v:
Blood. 112:1214-1222
VAF347 is a low-molecular-weight compound, which activates the aryl hydrocarbon receptor (AhR). Herein, we report that oral administration of a water-soluble derivative of VAF347 (VAG539) promotes long-term graft acceptance and active tolerance in Ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694ed868ad5eaf686c37f56b1c36fbbf
https://doi.org/10.1182/blood-2007-08-109843
https://doi.org/10.1182/blood-2007-08-109843
Autor:
Diana Mechtcheriakova, Nicole Urtz, Jury Sobanov, Maximilian Woisetschläger, Alexander Wlachos, Frédéric Bornancin, Gerhard J. Zlabinger, Thomas Baumruker, Georg Stingl, Andreas Billich, Richard Cai, Roland Reuschel, Tamara Kopp, Barbara Zemann
Publikováno v:
Cellular Signalling. 19:748-760
Sphingosine 1-phosphate (S1P) levels in cells and, consequently, its bioactivity as a signalling molecule are controlled by the action of enzymes responsible for its synthesis and degradation. In the present report, we examined alterations in express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73ae272ce80a80bf3dabc21d0857e10
https://doi.org/10.1016/j.cellsig.2006.09.004
https://doi.org/10.1016/j.cellsig.2006.09.004
Autor:
Jérôme Pène, Jean-Michel Fabre, Jean-François Gauchat, Pascal Demoly, Nathalie Harrer, Laurence Guglielmi, Vera Boulay, Maximilian Woisetschläger, Hans Yssel
Publikováno v:
The Journal of Immunology. 177:5006-5013
IL-21 is a cytokine produced by CD4+ T cells that has been reported to regulate human, as well as, mouse T and NK cell function and to inhibit Ag-induced IgE production by mouse B cells. In the present study, we show that human rIL-21 strongly enhanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc191ff7d3db9fe9143bd63395c8006
https://doi.org/10.4049/jimmunol.177.8.5006
https://doi.org/10.4049/jimmunol.177.8.5006
Autor:
Alexandre Trifilieff, Adrian M. Stütz, Maximilian Woisetschläger, Louise A. Pickart, Thomas Baumruker, Eva Erika Prieschl-Strassmayr
Publikováno v:
The Journal of Immunology. 170:1789-1796
The onset of allergic inflammation in the lung is driven by a complex genetic program. This study shows that found in inflammatory zone (FIZZ)1 and FIZZ2, but not FIZZ3, gene expression was up-regulated 6 h after Ag challenge in a mouse model of acut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae533ddd864d1e8bca2fca7c805e073
https://doi.org/10.4049/jimmunol.170.4.1789
https://doi.org/10.4049/jimmunol.170.4.1789
Autor:
Maximilian Woisetschläger, Jutta Hoeck
Publikováno v:
The Journal of Immunology. 167:3216-3222
Allergic inflammatory conditions such as asthma are characterized by an accumulation of eosinophils at sites of inflammation. Eotaxin-3/CCL26 is a member of the family of CC chemokines, which are known to be potent chemoattractants for eosinophils. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914944fefb3655f15c3604ebe60fb5c2
https://doi.org/10.4049/jimmunol.167.6.3216
https://doi.org/10.4049/jimmunol.167.6.3216
Autor:
Katsuaki Hoshino, Y. Iwasaki, K. Mair, H. Katayama, W. Reindl, A. Schlitzer, Kazuhiko Yamamoto, Miriam Merad, T. Hirashima, S. Richter, D. Hashimoto, Michael S. Diamond, Maximilian Woisetschläger, Izumi Sasaki, Deepta Bhattacharya, R. Vogelmann, Satoshi Takaki, K. Anne, D. Waltenberger, R. Hamamichi, Li Wu, N. Yin, M. Greter, E. Hamada, K. Liu, Kiyoshi Takatsu, Michel C. Nussenzweig, H. Strobl, J. Koyama, Florent Ginhoux, R. Stanley, J. Helft, Ken Shortman, Lynn M. Corcoran, Masanori Iseki, Tsuneyasu Kaisho, P. Sathe, J. H. Niess, S. Lira, W. E. Purtha, Jonathan S. Bromberg, L. Nagy, B. Platzer, M. Bogunovic
Publikováno v:
International Immunology. 22:iii24-iii26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b9bddba1a74d2c1cde26cdab78ac490
https://doi.org/10.1093/intimm/dxq310
https://doi.org/10.1093/intimm/dxq310
Autor:
K. Brown, I.G. Reischl, S. Peiritsch, L. Wheat, G.C. Mudde, Maximilian Woisetschläger, G R Dubois
Publikováno v:
Clinical & Experimental Allergy. 30:1033-1040
Background The FceRI subunit composition and kinetic of expression differ between antigen-presenting cells and mast cells. Up to now, there has been no human in vitro model available that mimics the characteristics on monocytes. Objective The charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f76581860786911534e34a07ff9d4d1
https://doi.org/10.1046/j.1365-2222.2000.00859.x
https://doi.org/10.1046/j.1365-2222.2000.00859.x