Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Maximilian Wiesmann"'
Autor:
Gemma Solé-Guardia, Matthijs Luijten, Bram Geenen, Jurgen A. H. R. Claassen, Geert Litjens, Frank-Erik de Leeuw, Maximilian Wiesmann, Amanda J. Kiliaan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract White matter hyperintensities (WMH) are the most prevalent markers of cerebral small vessel disease (SVD), which is the major vascular risk factor for dementia. Microvascular pathology and neuroinflammation are suggested to drive the transit
Externí odkaz:
https://doaj.org/article/7ff59429590144cd9d0b636d08691e0d
Autor:
Emma Custers, Debby Vreeken, Frank Schuren, Tim J. van den Broek, Lieke van Dongen, Bram Geenen, Ivo de Blaauw, Maximilian Wiesmann, Eric J. Hazebroek, Robert Kleemann, Amanda J. Kiliaan
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 918 (2024)
Obesity is a multifactorial disease associated with low-grade inflammation. The gut is thought to be involved in obesity-related inflammation, as it is continuously exposed to antigens from food, microbiota and metabolites. However, the exact underly
Externí odkaz:
https://doaj.org/article/e42061bb6b974da9ae2228dd9c61dbcd
Autor:
Gemma Sole-Guardia, Emma Custers, Arthur de Lange, Elyne Clijncke, Bram Geenen, Jose Gutierrez, Benno Kusters, Jurgen Claassen, Frank-Erik de Leeuw, Maximilian Wiesmann, Amanda Kiliaan
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100313- (2024)
Introduction: The major vascular cause of dementia is cerebral small vessel disease (SVD). The diagnosis of SVD relies on MRI findings, including white matter hyperintensities (WMH) amongst others. Chronic hypertension and neuroinflammation are recog
Externí odkaz:
https://doaj.org/article/de574cd8413c4afcb32aff06ed68dc6f
Autor:
Gemma Solé-Guardia, Emma Custers, Arthur de Lange, Elyne Clijncke, Bram Geenen, Jose Gutierrez, Benno Küsters, Jurgen A. H. R. Claassen, Frank-Erik de Leeuw, Maximilian Wiesmann, Amanda J. Kiliaan
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract The major vascular cause of dementia is cerebral small vessel disease (SVD), including white matter hyperintensities (WMH) amongst others. While the underlying pathology of SVD remains unclear, chronic hypertension and neuroinflammation are
Externí odkaz:
https://doaj.org/article/f8b63c80620f4e1d9ffcea9812722dfc
Autor:
Anouk C. Tengeler, Sarita A. Dam, Maximilian Wiesmann, Jilly Naaijen, Miranda van Bodegom, Clara Belzer, Pieter J. Dederen, Vivienne Verweij, Barbara Franke, Tamas Kozicz, Alejandro Arias Vasquez, Amanda J. Kiliaan
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-14 (2020)
Abstract Background The impact of the gut microbiota on host physiology and behavior has been relatively well established. Whether changes in microbial composition affect brain structure and function is largely elusive, however. This is important as
Externí odkaz:
https://doaj.org/article/b3adc87a77fc4dd1baf4caaa08e5b0a7
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Stroke treatment is limited to time-critical thrombectomy and rehabilitation by physiotherapy. Studies report beneficial effects of exercise; however, a knowledge gap exists regarding underlying mechanisms that benefit recovery of brain networks and
Externí odkaz:
https://doaj.org/article/cff0f2cefebc499faa729aca6e53b5b1
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Quantitative characterization of mouse activity, locomotion and walking patterns requires the monitoring of position and activity over long periods of time. Manual behavioral phenotyping, however, is time and skill-intensive, vulnerable to researcher
Externí odkaz:
https://doaj.org/article/61b1f1a06db24fb1ba075a979d099873
Autor:
Maximilian Wiesmann, Valerio Zerbi, Diane Jansen, Roy Haast, Dieter Lütjohann, Laus M. Broersen, Arend Heerschap, Amanda J. Kiliaan
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
APOE ε4 (apoE4) polymorphism is the main genetic determinant of sporadic Alzheimer’s disease (AD). A dietary approach (Fortasyn) including docosahexaenoic acid, eicosapentaenoic acid, uridine, choline, phospholipids, folic acid, vitamins B12, B6,
Externí odkaz:
https://doaj.org/article/66310479963542e38ccb9d66b05caf7e
Autor:
Diane Jansen, Valerio Zerbi, Ilse A C Arnoldussen, Maximilian Wiesmann, Anne Rijpma, Xiaotian T Fang, Pieter J Dederen, Martina P C Mutsaers, Laus M Broersen, Dieter Lütjohann, Malgorzata Miller, Leo A B Joosten, Arend Heerschap, Amanda J Kiliaan
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75393 (2013)
Recent studies have focused on the use of multi-nutrient dietary interventions in search of alternatives for the treatment and prevention of Alzheimer's disease (AD). In this study we investigated to which extent long-term consumption of two specific
Externí odkaz:
https://doaj.org/article/c3efca1f1dcd492ba7e536026746b104
Autor:
Klara J. Lohkamp, Anita M. van den Hoek, Gemma Solé-Guardia, Maria Lisovets, Talissa Alves Hoffmann, Konstantina Velanaki, Bram Geenen, Vivienne Verweij, Martine C. Morrison, Robert Kleemann, Maximilian Wiesmann, Amanda J. Kiliaan
Publikováno v:
Nutrients; Volume 15; Issue 7; Pages: 1716
Nutrients, 15
Nutrients, 15, 7
Nutrients, 15
Nutrients, 15, 7
Contains fulltext : 291954.pdf (Publisher’s version ) (Open Access) Exercise and dietary interventions are promising approaches to tackle obesity and its obesogenic effects on the brain. We investigated the impact of exercise and possible synergist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a285856fc3a6bce150a63d518d3fa9