Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Maximilian W M, Wintergerst"'
Autofluorescence-based tissue characterization enhances clinical prospects of light-sheet-microscopy
Autor:
Alice M. Jacob, Anna F. Lindemann, Julia Wagenpfeil, Sergej Geiger, Yannik C. Layer, Babak Salam, Sarah Panahabadi, Darius Kurt, Maximilian W. M. Wintergerst, Frank A. Schildberg, Daniel Kuetting, Ulrike I. Attenberger, Zeinab Abdullah, Alexander M. C. Böhner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Light sheet fluorescence microscopy (LSFM) is a transformative imaging method that enables the visualization of non-dissected specimen in real-time 3D. Optical clearing of tissues is essential for LSFM, typically employing toxic solvents. He
Externí odkaz:
https://doaj.org/article/9f4f3ba2b17c45cfa0544fa6cff24bbc
Autor:
Lukas Goerdt, Moritz Berger, Julie Jungblut, Jose Luis Rodriguez Garcia, Kristina Pfau, Philipp Herrmann, Frank G. Holz, Maximilian W. M. Wintergerst
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Macular Telangiectasia Type 2 (MacTel) is a chronic, progressive disease of the central retina characterized by vascular and neurodegenerative changes. As there is currently no treatment for non-neovascular MacTel, there is a dearth for biom
Externí odkaz:
https://doaj.org/article/a54a9b1d15ec4042aaeeda379caa7c6d
Autor:
Lisa Gittel, Jeany Q. Li, Jennifer Dell, Maximilian W. M. Wintergerst, Carsten Heinz, Robert P. Finger, Jan Henrik Terheyden
Publikováno v:
Journal of Ophthalmic Inflammation and Infection, Vol 14, Iss 1, Pp 1-6 (2024)
Abstract Introduction The National Eye Institute Visual Function Questionnaire (NEI VFQ) is a common patient-reported outcome measure (PROM) in uveitis trials. Its psychometric properties using state-of-the-art scoring based on Rasch models, a latent
Externí odkaz:
https://doaj.org/article/d76887f1fee040dca4e94780025c490a
Autor:
Maximilian W. M. Wintergerst, Nicholas R. Merten, Moritz Berger, Jan H. Terheyden, Lennart J. Overbeck, Matthias Schmid, Frank G. Holz, Robert P. Finger
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract As most rare diseases, intermediate uveitis lacks reliable endpoints necessary for randomized clinical trials. Therefore, we investigated longitudinal changes of retinal and choriocapillaris perfusion on optical coherence tomography angiogra
Externí odkaz:
https://doaj.org/article/93ecf9b516954f02a9c3261bce6eff89
Autor:
Jan Henrik Terheyden, David J. Fink, Karl Mercieca, Maximilian W. M. Wintergerst, Frank G. Holz, Robert P. Finger
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background With a rising prevalence of age-related eye diseases, prevention and early diagnosis of these conditions are key goals of public eye health. Disease-related knowledge in the general public supports these goals but there is little
Externí odkaz:
https://doaj.org/article/79df10f293554c51b69469550b80f712
Autor:
Jan Henrik Terheyden, Johanna Gerhards, Reglind A. D. Ost, Maximilian W. M. Wintergerst, Frank G. Holz, Robert P. Finger
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Visual impairment is an independent risk factor for falling. Whether this extends to patient-reported visual difficulties has not been assessed to date. We have evaluated whether patient-reported visual difficulties in low-contras
Externí odkaz:
https://doaj.org/article/4c65c7a06e2a47799762473c5fa11f02
Autor:
Anne Caroline Wolpers, Thomas Welchowski, Alexander Sedaghat, Maximilian W. M. Wintergerst, Baravan Al-Kassou, Robert P. Finger, Jan Henrik Terheyden
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Cerebral embolization is a known complication of transcatheter aortic valve implantation (TAVI) but the effect of the procedure on the ocular perfusion is currently unclear. Thus, we investigated post-procedural morphologic and perfusion cha
Externí odkaz:
https://doaj.org/article/7b41923204ae4caab631ee93b4c08f03
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Drusen are an important biomarker for age-related macular degeneration (AMD). Their accurate segmentation based on optical coherence tomography (OCT) is therefore relevant to the detection, staging, and treatment of disease. Since manual OCT
Externí odkaz:
https://doaj.org/article/3be9e25091f549ee8d4c46396522d0fc
Autor:
Matthias M. Mauschitz, Markus Zeller, Pradeep Sagar, Suchitra Biswal, Gabriela Guzman, Jan H. Terheyden, Carsten H. Meyer, Frank G. Holz, Carsten Heinz, Uwe Pleyer, Robert P. Finger, Maximilian W. M. Wintergerst
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 515 (2024)
Fundus autofluorescence (FAF) is a prompt and non-invasive imaging modality helpful in detecting pathological abnormalities within the retina and the choroid. This narrative review and case series provides an overview on the current application of FA
Externí odkaz:
https://doaj.org/article/b128590fa26f441da8d807e598c919fc
Autor:
Davide Garzone, Jan Henrik Terheyden, Olivier Morelle, Maximilian W. M. Wintergerst, Marlene Saßmannshausen, Steffen Schmitz-Valckenberg, Maximilian Pfau, Sarah Thiele, Stephen Poor, Sergio Leal, Frank G. Holz, Robert P. Finger, MACUSTAR Consortium
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Drusen are hallmarks of early and intermediate age-related macular degeneration (AMD) but their quantification remains a challenge. We compared automated drusen volume measurements between different OCT devices. We included 380 eyes from 200
Externí odkaz:
https://doaj.org/article/29e756f5d1034584915d1208b2514c47