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pro vyhledávání: '"Maximilian Steve Beck"'
Autor:
Britta Nubbemeyer, Ajay Abisheck Paul George, Toni Kühl, Anna Pepanian, Maximilian Steve Beck, Rahma Maghraby, Maryam Shetab Boushehri, Maximilian Muehlhaupt, Eva Marie Pfeil, Suvi Katariina Annala, Hermann Ammer, Diana Imhof, Dehua Pei
Publikováno v:
ACS Chemical Biology. 17:463-473
Chemical probes that specifically modulate the activity of heterotrimeric G proteins provide excellent tools for investigating G protein-mediated cell signaling. Herein, we report a family of selective peptidyl Gαi/s modulators derived from peptide
Autor:
Senada Nozinovic, Dieter Willbold, Toni Kühl, Dirk Menche, Benjamin Franz Syllwasschy, Anuradha Ramoji, Diana Imhof, Ivona Družeta, Maximilian Steve Beck, Ute Neugebauer, Marie-Thérèse Hopp, Oliver Ohlenschläger
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1864:129603
Background & motivation Peptides and proteins can interact with heme through His, Tyr, or Cys in heme-regulatory motifs (HRMs). The Cys-Pro dipeptide is a well investigated HRM, but for His and Tyr such a distinct motif is currently unknown. In addit